Pharmacologic activity, safety, and preliminary efficacy of GEN3009, a CD37-targeting DuoHexaBody, in relapsed or refractory B-cell non-Hodgkin's lymphoma.
Awan FT, Gamse JT, Overdijk MB, Breij ECW, Jure-Kunkel M, Sanghavi K, Brady LK, Guan M, Verbrugge I, Chen J, Gong N, Gillespie M, Tees M, Gallogly M, Hutchings M, Christensen JH, Sureda A, Cordoba R, Ahmed S, Woei-A-Jin FJSH, Abrisqueta P, Giné E, Roost Clausen M, Bhat SA, Gopal AK, Chamuleau MED.
Awan FT, et al. Among authors: gopal ak.
J Immunother Cancer. 2026 Jul 7;14(7):e014311. doi: 10.1136/jitc-2025-014311.
J Immunother Cancer. 2026.
PMID: 42413982
Free PMC article.
Clinical Trial.
GEN3009 was assessed in non-clinical studies and a phase 1 dose-escalation study of B-cell non-Hodgkin's lymphoma (B-NHL). METHODS: After a non-clinical toxicity study was conducted in cynomolgus monkeys, a phase 1, first-in-human, open-label, multicenter dose-escal …
GEN3009 was assessed in non-clinical studies and a phase 1 dose-escalation study of B-cell non-Hodgkin's lymphoma (B-NHL). MET …