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Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants.
Timpson NJ, Forouhi NG, Brion MJ, Harbord RM, Cook DG, Johnson P, McConnachie A, Morris RW, Rodriguez S, Luan J, Ebrahim S, Padmanabhan S, Watt G, Bruckdorfer KR, Wareham NJ, Whincup PH, Chanock S, Sattar N, Lawlor DA, Davey Smith G. Timpson NJ, et al. Am J Clin Nutr. 2010 Aug;92(2):375-82. doi: 10.3945/ajcn.2010.29438. Epub 2010 Jun 2. Am J Clin Nutr. 2010. PMID: 20519558 Free PMC article.
Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with L-ascorbic acid.
Wade KH, Forouhi NG, Cook DG, Johnson P, McConnachie A, Morris RW, Rodriguez S, Ye Z, Ebrahim S, Padmanabhan S, Watt G, Bruckdorfer KR, Wareham NJ, Whincup PH, Chanock S, Sattar N, Lawlor DA, Davey Smith G, Timpson NJ. Wade KH, et al. Am J Clin Nutr. 2015 Jan;101(1):202-9. doi: 10.3945/ajcn.114.092981. Epub 2014 Nov 19. Am J Clin Nutr. 2015. PMID: 25527764 Free PMC article.
Inflammation and not cardiovascular risk factors is associated with short leukocyte telomere length in 13- to 16-year-old adolescents.
Masi S, Nightingale CM, Day IN, Guthrie P, Rumley A, Lowe GD, von Zglinicki T, D'Aiuto F, Taddei S, Klein N, Salpea K, Cook DG, Humphries SE, Whincup PH, Deanfield JE. Masi S, et al. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):2029-34. doi: 10.1161/ATVBAHA.112.250589. Epub 2012 Jun 7. Arterioscler Thromb Vasc Biol. 2012. PMID: 22679311