095605/Wellcome Trust/United Kingdom[Grant Number] - Search Results

Year	Number of Results
2011	2
2012	4
2013	1
2014	1
2015	1
2016	1
2017	1
2022	0

1

The 'active life' of Hsp90 complexes.

Prodromou C. Prodromou C. Biochim Biophys Acta. 2012 Mar;1823(3):614-23. doi: 10.1016/j.bbamcr.2011.07.020. Epub 2011 Aug 4. Biochim Biophys Acta. 2012. PMID: 21840346 Free PMC article. Review.

2

Regulatory Mechanisms of Hsp90.

Prodromou C. Prodromou C. Biochem Mol Biol J. 2017 Jan 30;3(1):2. doi: 10.21767/2471-8084.100030. Biochem Mol Biol J. 2017. PMID: 28289734 Free PMC article.

3

Tah1 helix-swap dimerization prevents mixed Hsp90 co-chaperone complexes.

Morgan RM, Pal M, Roe SM, Pearl LH, Prodromou C. Morgan RM, et al. Acta Crystallogr D Biol Crystallogr. 2015 May;71(Pt 5):1197-206. doi: 10.1107/S1399004715004551. Epub 2015 Apr 25. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 25945584 Free PMC article.

4

Cooperation of local motions in the Hsp90 molecular chaperone ATPase mechanism.

Schulze A, Beliu G, Helmerich DA, Schubert J, Pearl LH, Prodromou C, Neuweiler H. Schulze A, et al. Nat Chem Biol. 2016 Aug;12(8):628-35. doi: 10.1038/nchembio.2111. Epub 2016 Jun 20. Nat Chem Biol. 2016. PMID: 27322067 Free PMC article.

5

Structural basis for phosphorylation-dependent recruitment of Tel2 to Hsp90 by Pih1.

Pal M, Morgan M, Phelps SE, Roe SM, Parry-Morris S, Downs JA, Polier S, Pearl LH, Prodromou C. Pal M, et al. Structure. 2014 Jun 10;22(6):805-18. doi: 10.1016/j.str.2014.04.001. Epub 2014 May 1. Structure. 2014. PMID: 24794838 Free PMC article.

6

ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system.

Polier S, Samant RS, Clarke PA, Workman P, Prodromou C, Pearl LH. Polier S, et al. Nat Chem Biol. 2013 May;9(5):307-12. doi: 10.1038/nchembio.1212. Epub 2013 Mar 17. Nat Chem Biol. 2013. PMID: 23502424 Free PMC article.

7

Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.

Xu W, Mollapour M, Prodromou C, Wang S, Scroggins BT, Palchick Z, Beebe K, Siderius M, Lee MJ, Couvillon A, Trepel JB, Miyata Y, Matts R, Neckers L. Xu W, et al. Mol Cell. 2012 Aug 10;47(3):434-43. doi: 10.1016/j.molcel.2012.05.015. Epub 2012 Jun 21. Mol Cell. 2012. PMID: 22727666 Free PMC article.

8

Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studies.

Day JE, Sharp SY, Rowlands MG, Aherne W, Hayes A, Raynaud FI, Lewis W, Roe SM, Prodromou C, Pearl LH, Workman P, Moody CJ. Day JE, et al. ACS Chem Biol. 2011 Dec 16;6(12):1339-47. doi: 10.1021/cb200196e. Epub 2011 Oct 4. ACS Chem Biol. 2011. PMID: 21932796

9

Structure of the TPR domain of AIP: lack of client protein interaction with the C-terminal α-7 helix of the TPR domain of AIP is sufficient for pituitary adenoma predisposition.

Morgan RM, Hernández-Ramírez LC, Trivellin G, Zhou L, Roe SM, Korbonits M, Prodromou C. Morgan RM, et al. PLoS One. 2012;7(12):e53339. doi: 10.1371/journal.pone.0053339. Epub 2012 Dec 31. PLoS One. 2012. PMID: 23300914 Free PMC article.

10

CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression.

Truman AW, Kristjansdottir K, Wolfgeher D, Hasin N, Polier S, Zhang H, Perrett S, Prodromou C, Jones GW, Kron SJ. Truman AW, et al. Cell. 2012 Dec 7;151(6):1308-18. doi: 10.1016/j.cell.2012.10.051. Cell. 2012. PMID: 23217712 Free PMC article.

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