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Formation of a heterooctameric complex between aspartate α-decarboxylase and its cognate activating factor, PanZ, is CoA-dependent.
Biochem Biophys Res Commun. 2012 Sep 28;426(3):350-5. doi: 10.1016/j.bbrc.2012.08.084. Epub 2012 Aug 24.
Biochem Biophys Res Commun. 2012.
PMID: 22940551
Free PMC article.
The Mechanism of Regulation of Pantothenate Biosynthesis by the PanD-PanZ·AcCoA Complex Reveals an Additional Mode of Action for the Antimetabolite N-Pentyl Pantothenamide (N5-Pan).
Arnott ZLP, Nozaki S, Monteiro DCF, Morgan HE, Pearson AR, Niki H, Webb ME.
Arnott ZLP, et al.
Biochemistry. 2017 Sep 19;56(37):4931-4939. doi: 10.1021/acs.biochem.7b00509. Epub 2017 Sep 7.
Biochemistry. 2017.
PMID: 28832133
Free PMC article.
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The structure of the PanD/PanZ protein complex reveals negative feedback regulation of pantothenate biosynthesis by coenzyme A.
Monteiro DCF, Patel V, Bartlett CP, Nozaki S, Grant TD, Gowdy JA, Thompson GS, Kalverda AP, Snell EH, Niki H, Pearson AR, Webb ME.
Monteiro DCF, et al.
Chem Biol. 2015 Apr 23;22(4):492-503. doi: 10.1016/j.chembiol.2015.03.017.
Chem Biol. 2015.
PMID: 25910242
Free PMC article.
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