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16,049 results

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Page 1
1,4-Dithiothreitol treatment ameliorates hematopoietic and intestinal injury in irradiated mice: Potential application of a treatment for acute radiation syndrome.
Li K, Zhang J, Cao J, Li X, Tian H. Li K, et al. Int Immunopharmacol. 2019 Nov;76:105913. doi: 10.1016/j.intimp.2019.105913. Epub 2019 Oct 15. Int Immunopharmacol. 2019. PMID: 31627170
Hence, antioxidants and thiol-reducing agents could have a potential protective effect against this complication. The dithiol compound 1,4-dithiothreitol (DTT) has been used in biochemistry, peptide/protein chemistry and clinical medicine. ...
Hence, antioxidants and thiol-reducing agents could have a potential protective effect against this complication. The dithiol compound 1 …
Kinetics of ascorbate and dithiothreitol oxidation by soluble copper, iron, and manganese, and 1,4-naphthoquinone: Influence of the species concentration and the type of fluid.
Expósito A, Maillo J, Uriarte I, Santibáñez M, Fernández-Olmo I. Expósito A, et al. Chemosphere. 2024 Aug;361:142435. doi: 10.1016/j.chemosphere.2024.142435. Epub 2024 May 24. Chemosphere. 2024. PMID: 38797213 Free article.
Acellular OP assays are the most used worldwide, mainly those based on ascorbic acid (AA) and dithiothreitol (DTT) depletion; OP values are calculated from AA/DTT concentration over time kinetic curves. ...In particular, the influence of the concentration of Cu(II), Fe(II) …
Acellular OP assays are the most used worldwide, mainly those based on ascorbic acid (AA) and dithiothreitol (DTT) depletion; OP valu …
Nucleophilic 1,4-additions for natural product discovery.
Cox CL, Tietz JI, Sokolowski K, Melby JO, Doroghazi JR, Mitchell DA. Cox CL, et al. ACS Chem Biol. 2014 Sep 19;9(9):2014-22. doi: 10.1021/cb500324n. Epub 2014 Jun 17. ACS Chem Biol. 2014. PMID: 24937678 Free PMC article.
Our strategy entails the use of a commercially available thiol, dithiothreitol, for the covalent labeling of activated alkenes by nucleophilic 1,4-addition. ...
Our strategy entails the use of a commercially available thiol, dithiothreitol, for the covalent labeling of activated alkenes by nuc …
The development of an endoplasmic reticulum-targeting fluorescent probe for the imaging of 1,4-dithiothreitol (DTT) in living cells.
Mehmood AH, Dong B, Lu Y, Song W, Sun Y, Lin W. Mehmood AH, et al. Anal Methods. 2021 May 21;13(19):2204-2208. doi: 10.1039/d0ay00443j. Epub 2021 Apr 27. Anal Methods. 2021. PMID: 33904541
1,4-Dithiothreitol (DTT) is a robust reducing agent that contributes significantly to the folding process of proteins and maintaining endoplasmic reticulum (ER) homeostasis. ...
1,4-Dithiothreitol (DTT) is a robust reducing agent that contributes significantly to the folding process of proteins a …
1,4-Dithiothreitol-induced alteration in histamine H1-agonist binding in guinea-pig cerebellum and cerebral cortex.
Donaldson J, Hill SJ. Donaldson J, et al. Eur J Pharmacol. 1986 Sep 23;129(1-2):25-31. doi: 10.1016/0014-2999(86)90332-8. Eur J Pharmacol. 1986. PMID: 3770075
The effect of the disulphide bond reducing agent 1,4-dithiothreitol (DTT) on the binding characteristics of the H1-selective ligand [3H]mepyramine has been examined in homogenates of guinea-pig cerebral cortex and cerebellum. ...
The effect of the disulphide bond reducing agent 1,4-dithiothreitol (DTT) on the binding characteristics of the H1-sele …
Reactions of aliphatic thiyl radicals in the solid state: photoisomerization of trans-4,5-dihydroxy-1,2-dithiacyclohexane and oxidation of dithiothreitol.
Barrón LB, Waterman KC, Offerdahl TJ, Munson E, Schöneich C. Barrón LB, et al. J Phys Chem A. 2005 Oct 20;109(41):9241-8. doi: 10.1021/jp052011q. J Phys Chem A. 2005. PMID: 16833264
Here, we demonstrate that such a sulfur transfer is not a general phenomenon of thiyl-radical reactions in the solid state, providing experimental evidence for a solid-state hydrogen-transfer reaction between a dithiyl radical, generated through the photolysis of trans-4,5-dihydr …
Here, we demonstrate that such a sulfur transfer is not a general phenomenon of thiyl-radical reactions in the solid state, providing experi …
1,4-Dithiothreitol-induced changes in histamine H1-agonist efficacy and affinity in the longitudinal smooth muscle of guinea-pig ileum.
Donaldson J, Hill SJ. Donaldson J, et al. Br J Pharmacol. 1987 Jan;90(1):263-71. doi: 10.1111/j.1476-5381.1987.tb16848.x. Br J Pharmacol. 1987. PMID: 2880626 Free PMC article.
The effect of 1,4-dithiothreitol (DTT) on histamine H1-receptor agonist affinity and efficacy has been investigated in longitudinal muscle strips of guinea-pig ileum. ...
The effect of 1,4-dithiothreitol (DTT) on histamine H1-receptor agonist affinity and efficacy has been investigated in …
1,4-Benzoquinone is a topoisomerase II poison.
Lindsey RH Jr, Bromberg KD, Felix CA, Osheroff N. Lindsey RH Jr, et al. Biochemistry. 2004 Jun 15;43(23):7563-74. doi: 10.1021/bi049756r. Biochemistry. 2004. PMID: 15182198
It is believed that benzene does not initiate leukemias directly, but rather generates DNA damage through a series of phenolic metabolites, especially 1,4-benzoquinone. The cellular consequences of 1,4-benzoquinone are consistent with those of topoisom …
It is believed that benzene does not initiate leukemias directly, but rather generates DNA damage through a series of phenolic metabolites, …
A new xanthene-based two-photon fluorescent probe for the imaging of 1,4-dithiothreitol (DTT) in living cells.
Wang C, Dong B, Kong X, Zhang N, Song W, Lin W. Wang C, et al. Luminescence. 2018 Sep;33(6):1048-1053. doi: 10.1002/bio.3507. Epub 2018 Jun 21. Luminescence. 2018. PMID: 29927540
1,4-Dithiothreitol (DTT) has wide applications in cell biology and biochemistry. Development of effective methods for monitoring DTT in biological systems is important for the safe handling and study of toxicity to humans. ...
1,4-Dithiothreitol (DTT) has wide applications in cell biology and biochemistry. Development of effective methods for m …
Two-photon imaging of 1,4-dithiothreitol (DTT) by a red-emissive fluorescent probe in living cells, tissues and animals.
Zhang N, Dong B, Kong X, Wang C, Song W, Lin W. Zhang N, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2018 Dec 5;205:528-533. doi: 10.1016/j.saa.2018.07.041. Epub 2018 Aug 1. Spectrochim Acta A Mol Biomol Spectrosc. 2018. PMID: 30077141
1,4-Dithiothreitol (DTT) is an important small-molecular reducing agent and has extensive applications in biochemistry, peptide/protein chemistry and clinical medicine. ...
1,4-Dithiothreitol (DTT) is an important small-molecular reducing agent and has extensive applications in biochemistry, …
16,049 results
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