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The following term was not found in PubMed: 5-tetramethyl-8-carbomethoxybicyclo
Page 1
1-Meth-oxy-3-o-tolyl-bicyclo-[2.2.2]oct-5-ene-2,2-dicarbonitrile.
Büyükgüngör O, Yavuz S, Odabaşoğlu M, Pamir O, Yıldırır Y. Büyükgüngör O, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 22;65(Pt 9):o2208. doi: 10.1107/S1600536809032474. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21577609 Free PMC article.
In the title compound, C(18)H(18)N(2)O, the cyclo-hexene and cyclo-hexane rings of the bicyclo-[2.2.2]oct-5-ene unit adopt distorted boat conformations. In the crystal, mol-ecules exist as C-HN hydrogen-bonded centrosymmetric R(2) (2)(14) …
In the title compound, C(18)H(18)N(2)O, the cyclo-hexene and cyclo-hexane rings of the bicyclo-[2.2.2]oct-5
Regio- and stereoselective indium triflate-mediated nucleophilic ring-opening reactions of 3-aza-2-oxabicyclo[2.2.1]hept-5-ene and -[2.2.2]oct-5-ene systems.
Yang B, Miller MJ. Yang B, et al. J Org Chem. 2009 Oct 16;74(20):7990-3. doi: 10.1021/jo9016343. J Org Chem. 2009. PMID: 19754105 Free PMC article.
Indium triflate-mediated nucleophilic ring-opening reactions of 3-aza-2-oxabicyclo[2.2.1]hept-5-ene and -[2.2.2]oct-5-ene systems with alcohols and water were investigated. ...When [2.2.2] bicyclic syste …
Indium triflate-mediated nucleophilic ring-opening reactions of 3-aza-2-oxabicyclo[2.2.1]hept-5-ene and -[2.2. …
Synthesis and transformations of di-endo-3-aminobicyclo-[2.2.2]oct-5-ene-2-carboxylic acid derivatives.
Palkó M, Sohár P, Fülöp F. Palkó M, et al. Molecules. 2011 Sep 7;16(9):7691-705. doi: 10.3390/molecules16097691. Molecules. 2011. PMID: 21900870 Free PMC article.
all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13) and all-endo-5-amino-6-(hydroxymethyl)bicyclo[2.2.2]octan-2-ol (10) were prepared via dihydro-1,3-oxazine or g-lactone intermediates by the stereos …
all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13) and all-endo-5-amino-6-(hydroxymethyl)bicy …
Syntheses of four enantiomers of 2,3-diendo- and 3-endo-aminobicyclo[2.2.2]oct-5-ene-2-exo-carboxylic acid and their saturated analogues.
Palkó M, Hänninen MM, Sillanpää R, Fülöp F. Palkó M, et al. Molecules. 2013 Dec 6;18(12):15080-93. doi: 10.3390/molecules181215080. Molecules. 2013. PMID: 24322492 Free PMC article.
Ethyl 2,3-diendo-3-aminobicyclo[2.2.2]oct-5-ene-2-carboxylate (()-1) was resolved with O,O'-dibenzoyltartaric acid via diastereomeric salt formation. The efficient synthesis of the enantiomers of 2,3-diendo- …
Ethyl 2,3-diendo-3-aminobicyclo[2.2.2]oct-5-ene-2-carboxylate (()-1) was reso …
Synthesis of new N-substituted cyclic imides with an expected anxiolytic activity. XIII. Derivatives of 1-methoxybicyclo[2.2.2]oct-5-ene-2,3-dicarboximide.
Kossakowski J, Krawiecka M. Kossakowski J, et al. Acta Pol Pharm. 2000 Nov;57 Suppl:53-6. Acta Pol Pharm. 2000. PMID: 11293265
The preparation of a number of derivatives of 1-methoxybicyclo[2.2.2]-oct-5-ene-2,3-dicarboximide possessing an expected anxiolytic activity has been described....
The preparation of a number of derivatives of 1-methoxybicyclo[2.2.2]-oct-5-ene-2,3- …
Synthesis and pharmacological profile of bicyclo[2.2.2]octane derivatives: N-(1-aryl-4-piperazinyl-butyl) derivatives of 7-isopropyl-6-methyl- and 1-isopropyl-4-methylbicyclo[2.2.2]oct-5-ene-2,3-dicarboxyimide.
Zawadowski T, Skowron AA, Suski S, Rump S, Jakowicz I. Zawadowski T, et al. Acta Pol Pharm. 1995 Mar-Apr;52(2):129-32. Acta Pol Pharm. 1995. PMID: 8960243
The new class of compounds characterized by anxiolytic or antidepressive properties, including a number of N-(1-aryl-4-piperazinylbutyl) derivatives of the two isomers: 7-isopropyl-6-methyl- and 1-isopropyl-4-methylbicyclo [2.2.2]oct-5
The new class of compounds characterized by anxiolytic or antidepressive properties, including a number of N-(1-aryl-4-piperazinylbut …
New 1,3-amino alcohols derived from enantiopure bridgehead beta-aminobicyclo[2.2.2]oct-5-ene-2-carboxylic acids.
André C, Calmès M, Escale F, Amblard M, Martinez J, Songis O. André C, et al. Amino Acids. 2012 Jul;43(1):415-21. doi: 10.1007/s00726-011-1097-6. Epub 2011 Oct 4. Amino Acids. 2012. PMID: 21968501
Constrained enantiopure bicyclic beta-amino acids derived from the asymmetric Diels-Alder reaction of the (R)-benzyl-4-(3-acryloyloxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)-benzoate and the 1-(benzyloxycarbonylamino)cyclohexadiene provide original templates for t …
Constrained enantiopure bicyclic beta-amino acids derived from the asymmetric Diels-Alder reaction of the (R)-benzyl-4-(3-acryloyloxy …
Synthesis of new N-substituted cyclic imides with an expected anxiolytic activity. XXIV. Derivatives of N-hydroxy-1-methoxybicyclo[2.2.2]oct-5-ene-2,3-dicarboximide.
Kossakowski J, Krawiecka M. Kossakowski J, et al. Acta Pol Pharm. 2003 May-Jun;60(3):177-82. Acta Pol Pharm. 2003. PMID: 14556485 Free article.
The preparation of a number of derivatives of N-hydroxy-1-methoxybicyclo[2.2.2]oct-5-ene-2,3-dicarboximide with an expected anxiolytic and antidepressive activity has been described....
The preparation of a number of derivatives of N-hydroxy-1-methoxybicyclo[2.2.2]oct-5-ene-2, …
Synthesis and serotonin binding site studies of some conformationally restricted indolylethylamine analogues based on 2-amino-3-(3'-indolyl)bicyclo[2.2.2]octane.
Schlecht MF, Tsarouhtsis D, Lipovac MN, Debler EA. Schlecht MF, et al. J Med Chem. 1990 Jan;33(1):386-94. doi: 10.1021/jm00163a062. J Med Chem. 1990. PMID: 2136918
The bicycloannulation reaction between cyclohexenone and indolyl enamines yields trans-3-(cyclic amino)-2-(3'-indolyl)bicyclo[2.2.2]octan-5-ones, and these adducts are conformationally restricted analogues of indolylethylamine (tryptamine) which …
The bicycloannulation reaction between cyclohexenone and indolyl enamines yields trans-3-(cyclic amino)-2-(3'-indolyl)bicyclo[ …
16 results