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The following term was not found in PubMed: 5-dimethyl-3-n-pentyl-2-oxabicyclo
Page 1
Umeclidinium.
[No authors listed] [No authors listed] 2023 Dec 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Dec 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999790 Free Books & Documents. Review.
Felodipine-diazabicyclo[2.2.2]octane-water (1/1/1).
Solanko KA, Surov AO, Perlovich GL, Bauer-Brandl A, Bond AD. Solanko KA, et al. Acta Crystallogr C. 2012 Nov;68(Pt 11):o456-8. doi: 10.1107/S0108270112043405. Epub 2012 Oct 31. Acta Crystallogr C. 2012. PMID: 23124462
The title compound, C(18)H(19)Cl(2)NO(4).C(6)H(12)N(2).H(2)O, is a cocrystal hydrate containing the active pharmaceutical ingredient felodipine and diazabicyclo[2.2.2]octane (DABCO). The DABCO and water molecules are linked through O-H...N hydrogen bon …
The title compound, C(18)H(19)Cl(2)NO(4).C(6)H(12)N(2).H(2)O, is a cocrystal hydrate containing the active pharmaceutical ingredient felodip …
Lean NAFLD: A Distinct Entity Shaped by Differential Metabolic Adaptation.
Chen F, Esmaili S, Rogers GB, Bugianesi E, Petta S, Marchesini G, Bayoumi A, Metwally M, Azardaryany MK, Coulter S, Choo JM, Younes R, Rosso C, Liddle C, Adams LA, Craxì A, George J, Eslam M. Chen F, et al. Hepatology. 2020 Apr;71(4):1213-1227. doi: 10.1002/hep.30908. Epub 2020 Jan 24. Hepatology. 2020. PMID: 31442319 Free article.
Tetracyclic Diterpenoid Synthesis Facilitated by ODI-Cascade Approaches to Bicyclo[3.2.1]octane Skeletons.
Gao K, Hu J, Ding H. Gao K, et al. Acc Chem Res. 2021 Feb 16;54(4):875-889. doi: 10.1021/acs.accounts.0c00798. Epub 2021 Jan 28. Acc Chem Res. 2021. PMID: 33508196
Among them, more than three-quarters share a bridged bicyclo[3.2.1]octane subunit, which is also an important branching point in biosynthesis en route to the other types of bicyclic scaffolds, such as bicyclo[2.2.2]-, bicyclo[3.3.0]-, and tricyclo[3.2.1.0]octanes. C …
Among them, more than three-quarters share a bridged bicyclo[3.2.1]octane subunit, which is also an important branching point in bios …
Halogen-bonded adduct of 1,2-dibromo-1,1,2,2-tetrafluoroethane and 1,4-diazabicyclo[2.2.2]octane.
Brisdon AK, Muneer AM, Pritchard RG. Brisdon AK, et al. Acta Crystallogr C Struct Chem. 2015 Oct;71(Pt 10):900-2. doi: 10.1107/S2053229615016472. Epub 2015 Sep 18. Acta Crystallogr C Struct Chem. 2015. PMID: 26422219 Free article.
Typical halogen-bonding systems involve a noncovalent interaction between a Lewis base, such as an amine, as an acceptor and a halogen atom of a halofluorocarbon as a donor. Vapour-phase diffusion of 1,4-diazabicyclo[2.2.2]octane (DABCO) with …
Typical halogen-bonding systems involve a noncovalent interaction between a Lewis base, such as an amine, as an acceptor and a halogen atom …
Synthesis of 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane, and 2-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, a class of potent nicotinic acetylcholine receptor-ligands.
Bhatti BS, Strachan JP, Breining SR, Miller CH, Tahiri P, Crooks PA, Deo N, Day CS, Caldwell WS. Bhatti BS, et al. J Org Chem. 2008 May 2;73(9):3497-507. doi: 10.1021/jo800028q. Epub 2008 Mar 26. J Org Chem. 2008. PMID: 18363376
In an attempt to generate nicotinic acetylcholine receptor (nAChR) ligands selective for the alpha4beta2 and alpha7 subtype receptors we designed and synthesized constrained versions of anabasine, a naturally occurring nAChR ligand. 2-(Pyridin-3-yl)-1-azabicyclo[2. …
In an attempt to generate nicotinic acetylcholine receptor (nAChR) ligands selective for the alpha4beta2 and alpha7 subtype receptors we des …
Cubane, Bicyclo[1.1.1]pentane and Bicyclo[2.2.2]octane: Impact and Thermal Sensitiveness of Carboxyl-, Hydroxymethyl- and Iodo-substituents.
Dallaston MA, Houston SD, Williams CM. Dallaston MA, et al. Chemistry. 2020 Sep 16;26(52):11966-11970. doi: 10.1002/chem.202001658. Epub 2020 Aug 20. Chemistry. 2020. PMID: 32820575
With the burgeoning interest in cage motifs for bioactive molecule discovery, and the recent disclosure of 1,4-cubane-dicarboxylic acid impact sensitivity, more research into the safety profiles of cage scaffolds is required. Therefore, the impact sensitivity and thermal d …
With the burgeoning interest in cage motifs for bioactive molecule discovery, and the recent disclosure of 1,4-cubane-dicarboxylic ac …
Agallolides A-M, including two rearranged ent-atisanes featuring a bicyclo[3.2.1]octane motif, from the Chinese Excoecaria agallocha.
Jiang ZP, Yu Y, Shen L. Jiang ZP, et al. Bioorg Chem. 2020 Nov;104:104206. doi: 10.1016/j.bioorg.2020.104206. Epub 2020 Aug 29. Bioorg Chem. 2020. PMID: 32911189
Thirteen new diterpenoid compounds, named agallolides A-M (1-13), including ten ent-atisanes, were isolated from the stems and twigs of the Chinese semi-mangrove plant, Excoecaria agallocha. Most notably, agallolides A (1) and B (2) are two rearranged ent-atisanes f …
Thirteen new diterpenoid compounds, named agallolides A-M (1-13), including ten ent-atisanes, were isolated from the stems and twigs …
Enantioselective Total Synthesis of (+)-Jungermatrobrunin A.
Wu J, Kadonaga Y, Hong B, Wang J, Lei X. Wu J, et al. Angew Chem Int Ed Engl. 2019 Aug 5;58(32):10879-10883. doi: 10.1002/anie.201903682. Epub 2019 Jul 3. Angew Chem Int Ed Engl. 2019. PMID: 31056826
A concise and enantioselective total synthesis of (+)-jungermatrobrunin A (1), which features a unique bicyclo[3.2.1]octene ring skeleton with an unprecedented peroxide bridge, was accomplished in 13 steps by making use of a late-stage visible-light-mediated Schenck …
A concise and enantioselective total synthesis of (+)-jungermatrobrunin A (1), which features a unique bicyclo[3.2.1]octene ri …
177 results