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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3.
Seth RB, Sun L, Ea CK, Chen ZJ. Seth RB, et al. Cell. 2005 Sep 9;122(5):669-82. doi: 10.1016/j.cell.2005.08.012. Cell. 2005. PMID: 16125763 Free article.
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity.
Li XD, Sun L, Seth RB, Pineda G, Chen ZJ. Li XD, et al. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17717-22. doi: 10.1073/pnas.0508531102. Epub 2005 Nov 21. Proc Natl Acad Sci U S A. 2005. PMID: 16301520 Free PMC article.
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