13078/CRUK_/Cancer Research UK/United Kingdom[Grant Number] - Search Results

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Year	Number of Results
2010	1
2011	2
2012	1
2013	2
2014	2
2016	1
2021	0

Page 1

Protein ADP-ribosylation and the cellular response to DNA strand breaks.

Caldecott KW. Caldecott KW. DNA Repair (Amst). 2014 Jul;19:108-13. doi: 10.1016/j.dnarep.2014.03.021. Epub 2014 Apr 20. DNA Repair (Amst). 2014. PMID: 24755000 Review.

One ring to bring them all--the role of Ku in mammalian non-homologous end joining.

Grundy GJ, Moulding HA, Caldecott KW, Rulten SL. Grundy GJ, et al. DNA Repair (Amst). 2014 May;17:30-8. doi: 10.1016/j.dnarep.2014.02.019. Epub 2014 Mar 26. DNA Repair (Amst). 2014. PMID: 24680220 Review.

PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).

Grundy GJ, Polo LM, Zeng Z, Rulten SL, Hoch NC, Paomephan P, Xu Y, Sweet SM, Thorne AW, Oliver AW, Matthews SJ, Pearl LH, Caldecott KW. Grundy GJ, et al. Nat Commun. 2016 Aug 17;7:12404. doi: 10.1038/ncomms12404. Nat Commun. 2016. PMID: 27530147 Free PMC article.

PARP-3 and APLF function together to accelerate nonhomologous end-joining.

Rulten SL, Fisher AE, Robert I, Zuma MC, Rouleau M, Ju L, Poirier G, Reina-San-Martin B, Caldecott KW. Rulten SL, et al. Mol Cell. 2011 Jan 7;41(1):33-45. doi: 10.1016/j.molcel.2010.12.006. Mol Cell. 2011. PMID: 21211721 Free article.

APLF promotes the assembly and activity of non-homologous end joining protein complexes.

Grundy GJ, Rulten SL, Zeng Z, Arribas-Bosacoma R, Iles N, Manley K, Oliver A, Caldecott KW. Grundy GJ, et al. EMBO J. 2013 Jan 9;32(1):112-25. doi: 10.1038/emboj.2012.304. Epub 2012 Nov 23. EMBO J. 2013. PMID: 23178593 Free PMC article.

TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.

Gómez-Herreros F, Romero-Granados R, Zeng Z, Alvarez-Quilón A, Quintero C, Ju L, Umans L, Vermeire L, Huylebroeck D, Caldecott KW, Cortés-Ledesma F. Gómez-Herreros F, et al. PLoS Genet. 2013;9(3):e1003226. doi: 10.1371/journal.pgen.1003226. Epub 2013 Mar 7. PLoS Genet. 2013. PMID: 23505375 Free PMC article.

TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.

Zeng Z, Cortés-Ledesma F, El Khamisy SF, Caldecott KW. Zeng Z, et al. J Biol Chem. 2011 Jan 7;286(1):403-9. doi: 10.1074/jbc.M110.181016. Epub 2010 Oct 28. J Biol Chem. 2011. PMID: 21030584 Free PMC article.

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