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1829 3
1830 2
1831 14
1832 3
1833 2
1838 15
1839 2
1840 2
1841 14
1842 33
1843 4
1844 3
1845 5
1846 1
1847 3
1849 13
1850 1
1852 2
1853 4
1854 5
1855 3
1856 2
1857 4
1858 10
1859 3
1860 4
1861 5
1862 26
1863 2
1864 5
1865 3
1866 3
1867 3
1868 9
1869 8
1870 3
1871 7
1872 1
1873 5
1874 5
1875 18
1876 30
1877 28
1878 3
1879 5
1880 3
1881 18
1882 4
1883 5
1884 35
1885 5
1886 10
1887 25
1888 11
1889 85
1890 8
1891 10
1892 9
1893 9
1894 13
1895 8
1896 13
1897 19
1898 8
1899 7
1900 8
1901 4
1902 54
1903 6
1904 111
1905 11
1906 9
1907 7
1908 11
1909 10
1910 17
1911 17
1912 8
1913 107
1914 6
1915 406
1916 8
1917 9
1918 14
1919 10
1920 9
1921 14
1922 8
1923 545
1924 81
1925 8
1926 19
1927 11
1928 9
1929 12
1930 18
1931 14
1932 8
1933 64
1934 17
1935 20
1936 7
1937 6
1938 26
1939 7
1940 10
1941 23
1942 7
1943 178
1944 7
1945 62
1946 818
1947 486
1948 770
1949 643
1950 840
1951 1418
1952 582
1953 612
1954 1001
1955 615
1956 546
1957 766
1958 1416
1959 1241
1960 595
1961 979
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1965 2477
1966 821
1967 2358
1968 1632
1969 2205
1970 1411
1971 2126
1972 2030
1973 1309
1974 1685
1975 2919
1976 3476
1977 3097
1978 2835
1979 3675
1980 4370
1981 3696
1982 4447
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1984 4843
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1987 7236
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1989 6371
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The following term was not found in PubMed: 16126901.
Page 1
CGI-58: Versatile Regulator of Intracellular Lipid Droplet Homeostasis.
Yu L, Li Y, Grisé A, Wang H. Yu L, et al. Adv Exp Med Biol. 2020;1276:197-222. doi: 10.1007/978-981-15-6082-8_13. Adv Exp Med Biol. 2020. PMID: 32705602 Free PMC article. Review.
Comparative gene identification-58 (CGI-58), also known as alpha/beta-hydrolase domain-containing 5 (ABHD5), is a member of a large family of proteins containing an alpha/beta-hydrolase-fold. ...CGI-58, however, has ATGL-independent functions. Distinct phenot …
Comparative gene identification-58 (CGI-58), also known as alpha/beta-hydrolase domain-containing 5 (ABHD5), is a member of a …
Clinicalpathologic and Prognostic Significance of CGI-58 in Endometrial Cancer.
Shi Z, Luo X, Zhao H, Huang B, Wang Y, Chen X, Yu J. Shi Z, et al. J Cancer. 2021 Oct 28;12(24):7374-7379. doi: 10.7150/jca.61905. eCollection 2021. J Cancer. 2021. PMID: 35003357 Free PMC article.
Our findings demonstrate that CGI-58 is up-regulated in endometrial cancer and high CGI-58 expression is a poor prognostic marker for endometrial cancer. CGI-58 may be a potential contributor to endometrial cancer oncogenesis and progression....
Our findings demonstrate that CGI-58 is up-regulated in endometrial cancer and high CGI-58 expression is a poor prognostic mar …
Association between the levels of CGI-58 and lipoprotein lipase in the placenta of patients with preeclampsia.
Dong J, Wang M, Gao J, Liu J, Chen Y. Dong J, et al. Exp Ther Med. 2021 Oct;22(4):1129. doi: 10.3892/etm.2021.10563. Epub 2021 Aug 5. Exp Ther Med. 2021. PMID: 34466143 Free PMC article.
These results suggested that the expression of CGI-58 and LPL in the placenta was associated with the pathogenesis of preeclampsia and maternal lipids and the risk of preeclampsia was increased with decreasing expression levels of CGI-58 and LPL. Hence, CGI-58
These results suggested that the expression of CGI-58 and LPL in the placenta was associated with the pathogenesis of preeclampsia an …
Comparative gene identification-58/alpha/beta hydrolase domain 5: more than just an adipose triglyceride lipase activator?
Zierler KA, Zechner R, Haemmerle G. Zierler KA, et al. Curr Opin Lipidol. 2014 Apr;25(2):102-9. doi: 10.1097/MOL.0000000000000058. Curr Opin Lipidol. 2014. PMID: 24565921 Free PMC article. Review.
PURPOSE OF REVIEW: Comparative gene identification-58 (CGI-58) is a lipid droplet-associated protein that controls intracellular triglyceride levels by its ability to activate adipose triglyceride lipase (ATGL). ...SUMMARY: Although the function of CGI-58 in …
PURPOSE OF REVIEW: Comparative gene identification-58 (CGI-58) is a lipid droplet-associated protein that controls intracellul …
Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58.
Kulminskaya N, Rodriguez Gamez CF, Hofer P, Cerk IK, Dubey N, Viertlmayr R, Sagmeister T, Pavkov-Keller T, Zechner R, Oberer M. Kulminskaya N, et al. J Lipid Res. 2024 Jan;65(1):100491. doi: 10.1016/j.jlr.2023.100491. Epub 2023 Dec 20. J Lipid Res. 2024. PMID: 38135254 Free PMC article.
Adipose triglyceride lipase (ATGL) plays a key role in intracellular lipolysis and can be coactivated upon interaction with the protein comparative gene identification-58 (CGI-58). The underlying molecular mechanism of ATGL stimulation by CGI-58 is incomplete …
Adipose triglyceride lipase (ATGL) plays a key role in intracellular lipolysis and can be coactivated upon interaction with the protein comp …
Natural and synthetic CCK-58. Novel reagents for studying cholecystokinin physiology.
Reeve JR Jr, Eysselein VE, Ho FJ, Chew P, Vigna SR, Liddle RA, Evans C. Reeve JR Jr, et al. Ann N Y Acad Sci. 1994 Mar 23;713:11-21. doi: 10.1111/j.1749-6632.1994.tb44047.x. Ann N Y Acad Sci. 1994. PMID: 7514372 Review.
These studies gave clear indications that tertiary structure affects CCK-58 bioactivity, but the small quantities of CCK-58 available made it impossible to characterize completely how tertiary structure influenced bioactivity. ...Natural canine CCK-58 was equ …
These studies gave clear indications that tertiary structure affects CCK-58 bioactivity, but the small quantities of CCK-58 av …
CGI-58 Protein Acts as a Positive Regulator of Triacylglycerol Accumulation in Phaeodactylum tricornutum.
Shu Q, Pan Y, Hu H. Shu Q, et al. J Microbiol Biotechnol. 2023 Feb 28;33(2):242-250. doi: 10.4014/jmb.2209.09029. Epub 2022 Dec 1. J Microbiol Biotechnol. 2023. PMID: 36524337 Free PMC article.
Comparative gene identification-58 (CGI-58) is an activating protein of triacylglycerol (TAG) lipase. It has a variety of catalytic activities whereby it may play different roles in diverse organisms. In this study, a homolog of CGI-58 in Phaeodactylum tricor …
Comparative gene identification-58 (CGI-58) is an activating protein of triacylglycerol (TAG) lipase. It has a variety of cata …
A novel HLA-B allele: HLA-B*58:01:13.
Zheng JW, Xie JH, Sun Y, Xiang D. Zheng JW, et al. HLA. 2019 Jun;93(6):492-493. doi: 10.1111/tan.13498. Epub 2019 Mar 18. HLA. 2019. PMID: 30793531
The HLA-B*58:01:13 allele differs from B*58:01:01:01 by one nucleotide substitution at position 516....
The HLA-B*58:01:13 allele differs from B*58:01:01:01 by one nucleotide substitution at position 516....
Impact of HLA-B*58:01 allele and allopurinol-induced cutaneous adverse drug reactions: evidence from 21 pharmacogenetic studies.
Wu R, Cheng YJ, Zhu LL, Yu L, Zhao XK, Jia M, Wen CH, Long XZ, Tang T, He AJ, Zeng YY, Ma ZF, Zheng Z, Ni MZ, Cai GJ. Wu R, et al. Oncotarget. 2016 Dec 6;7(49):81870-81879. doi: 10.18632/oncotarget.13250. Oncotarget. 2016. PMID: 27835909 Free PMC article. Review.

The summary OR for allopurinol-induced CADRs among HLA-B*58:01 carriers was 82.77 (95% CI: 41.63 - 164.58, P < 10-5) and 100.87 (95% CI: 63.91 - 159.21, P < 10-5) in matched and population based studies, respectively. ...Our results indicated that allopurinol-

The summary OR for allopurinol-induced CADRs among HLA-B*58:01 carriers was 82.77 (95% CI: 41.63 - 164.58, P < 10-5) and 10

Construction and immune effect of an HPV16/18/58 trivalent therapeutic adenovirus vector vaccine.
Wan B, Qin L, Ma W, Wang H. Wan B, et al. Infect Agent Cancer. 2022 Feb 23;17(1):5. doi: 10.1186/s13027-022-00417-3. Infect Agent Cancer. 2022. PMID: 35197089 Free PMC article.
METHODS: The E6/E7 genes of HPV16/18/58 were point-mutated to abolish their transforming activity, and adenovirus (AD)-HPV16/18/58 mE6E7 adenovirus vaccine was constructed. ...CONCLUSION: We successfully constructed the HPV16/18/58 trivalent therapeutic adeno …
METHODS: The E6/E7 genes of HPV16/18/58 were point-mutated to abolish their transforming activity, and adenovirus (AD)-HPV16/18/58
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