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A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (HCHL) with acetyl-CoA and vanillin gives insights into substrate specificity and mechanism.
Biochem J. 2008 Sep 1;414(2):281-9. doi: 10.1042/BJ20080714.
Biochem J. 2008.
PMID: 18479250
Metabolism of ferulic acid to vanillin. A bacterial gene of the enoyl-SCoA hydratase/isomerase superfamily encodes an enzyme for the hydration and cleavage of a hydroxycinnamic acid SCoA thioester.
Gasson MJ, Kitamura Y, McLauchlan WR, Narbad A, Parr AJ, Parsons EL, Payne J, Rhodes MJ, Walton NJ.
Gasson MJ, et al.
J Biol Chem. 1998 Feb 13;273(7):4163-70. doi: 10.1074/jbc.273.7.4163.
J Biol Chem. 1998.
PMID: 9461612
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