Associations between [(18)F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample.
La Joie R, Bejanin A, Fagan AM, Ayakta N, Baker SL, Bourakova V, Boxer AL, Cha J, Karydas A, Jerome G, Maass A, Mensing A, Miller ZA, O'Neil JP, Pham J, Rosen HJ, Tsai R, Visani AV, Miller BL, Jagust WJ, Rabinovici GD.
La Joie R, et al.
Neurology. 2018 Jan 23;90(4):e282-e290. doi: 10.1212/WNL.0000000000004860. Epub 2017 Dec 27.
Neurology. 2018.
PMID: 29282337
Free PMC article.
In the full sample, cortical [(18)F]AV1451 was associated with all CSF biomarkers, most strongly with p-tau (r = 0.75 vs 0.57 for t-tau and -0.49 for Abeta(42)). When restricted to Abeta-positive patients with AD, [(18)F]AV1451 SUVR correlated modestly …
In the full sample, cortical [(18)F]AV1451 was associated with all CSF biomarkers, most strongly with p-tau (r = 0.75 vs 0.57 …