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A conserved tyrosyl-glutamyl catalytic dyad in evolutionarily linked enzymes: carbapenam synthetase and beta-lactam synthetase.
Biochemistry. 2009 Jun 9;48(22):4959-71. doi: 10.1021/bi900432n.
Biochemistry. 2009.
PMID: 19371088
Free PMC article.
Rate-limiting steps and role of active site Lys443 in the mechanism of carbapenam synthetase.
Arnett SO, Gerratana B, Townsend CA.
Arnett SO, et al.
Biochemistry. 2007 Aug 14;46(32):9337-45. doi: 10.1021/bi0618464. Epub 2007 Jul 21.
Biochemistry. 2007.
PMID: 17658887
Free PMC article.
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Crystal structure of carbapenam synthetase (CarA).
Miller MT, Gerratana B, Stapon A, Townsend CA, Rosenzweig AC.
Miller MT, et al.
J Biol Chem. 2003 Oct 17;278(42):40996-1002. doi: 10.1074/jbc.M307901200. Epub 2003 Jul 30.
J Biol Chem. 2003.
PMID: 12890666
Free article.
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