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1983 3
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Lymphokines in autoimmunity: relationship between interleukin-2 and interferon-gamma production in systemic lupus erythematosus.
Sibbitt WL Jr, Kenny C, Spellman CW, Ley KD, Bankhurst AD. Sibbitt WL Jr, et al. Clin Immunol Immunopathol. 1984 Aug;32(2):166-73. doi: 10.1016/0090-1229(84)90118-1. Clin Immunol Immunopathol. 1984. PMID: 6428789
Interleukin-2 (IL-2) and interferon (IFN) are potent immunoregulatory factors. ...IL-2 activity was determined employing HT-2, a cell line with an absolute growth requirement for IL-2. ...
Interleukin-2 (IL-2) and interferon (IFN) are potent immunoregulatory factors. ...IL-2 activity was determined employin …
Interferon-alpha regulation of lymphocyte function in systemic lupus erythematosus.
Sibbitt WL Jr, Froelich CJ, Bankhurst AD. Sibbitt WL Jr, et al. Clin Immunol Immunopathol. 1984 Jul;32(1):70-80. doi: 10.1016/0090-1229(84)90044-8. Clin Immunol Immunopathol. 1984. PMID: 6733982
The average NK cell activity was impaired in SLE patients (19.7 +/- 3.8 LU/10(7) cells; n = 22) compared to 24 normal controls (45.6 +/- 7.2 LU/10(7) cells; n = 24) (P less than 0.05). In addition, the response to IFN in the NK cell system was impaired in SLE (110.0 +/- 38 …
The average NK cell activity was impaired in SLE patients (19.7 +/- 3.8 LU/10(7) cells; n = 22) compared to 24 normal controls (45.6 +/- 7. …
Impaired natural killer cell function in systemic lupus erythematosus. Relationship to interleukin-2 production.
Sibbitt WL Jr, Likar L, Spellman CW, Bankhurst AD. Sibbitt WL Jr, et al. Arthritis Rheum. 1983 Nov;26(11):1316-20. doi: 10.1002/art.1780261103. Arthritis Rheum. 1983. PMID: 6605749
Immune regulation requires clonal expansion of regulatory T cells which is dependent on the presence of interleukin-2 (IL-2). Previously, both natural killer (NK) cell function and IL-2 production were found to be depressed in systemic lupus erythematosus (SL …
Immune regulation requires clonal expansion of regulatory T cells which is dependent on the presence of interleukin-2 (IL-2). …