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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1933 1
1949 1
1950 9
1951 9
1952 4
1953 8
1954 5
1955 3
1957 2
1958 4
1959 1
1960 2
1961 2
1962 1
1963 1
1964 5
1965 2
1966 1
1967 1
1969 4
1970 2
1971 1
1973 1
1974 1
1975 7
1976 1
1977 3
1978 4
1979 2
1980 5
1981 6
1982 6
1983 8
1984 6
1985 10
1986 13
1987 6
1988 4
1989 11
1990 13
1991 12
1992 19
1993 23
1994 21
1995 35
1996 32
1997 30
1998 26
1999 34
2000 33
2001 39
2002 23
2003 35
2004 36
2005 28
2006 51
2007 48
2008 47
2009 57
2010 58
2011 44
2012 44
2013 55
2014 63
2015 43
2016 45
2017 48
2018 39
2019 53
2020 58
2021 53
2022 61
2023 54
2024 19

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1,428 results

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Page 1
Gentisic Acid Stimulates Keratinocyte Proliferation through ERK1/2 Phosphorylation.
Kim M, Kim J, Shin YK, Kim KY. Kim M, et al. Int J Med Sci. 2020 Feb 24;17(5):626-631. doi: 10.7150/ijms.36484. eCollection 2020. Int J Med Sci. 2020. PMID: 32210712 Free PMC article.
Gentisic acid improved HaCaT cell proliferation by over 20% in MTT assay. ...Thus, our study indicates that gentisic acid promotes the proliferation of keratinocyte by phosphorylation of ERK1/2....
Gentisic acid improved HaCaT cell proliferation by over 20% in MTT assay. ...Thus, our study indicates that gentisic …
Gentisic acid ameliorates type 2 diabetes induced by Nicotinamide-Streptozotocin in male mice by attenuating pancreatic oxidative stress and inflammation through modulation of Nrf2 and NF-B pathways.
Razliqi RN, Ahangarpour A, Mard SA, Khorsandi L. Razliqi RN, et al. Life Sci. 2023 Jul 15;325:121770. doi: 10.1016/j.lfs.2023.121770. Epub 2023 May 14. Life Sci. 2023. PMID: 37192699
AIMS: There is a close link between oxidative stress, inflammation, and type 2 diabetes mellitus (T2DM). Gentisic acid (GA) is a di-phenolic compound and an active metabolite of aspirin that possesses antioxidant and anti-inflammatory properties, but its potential a …
AIMS: There is a close link between oxidative stress, inflammation, and type 2 diabetes mellitus (T2DM). Gentisic acid (GA) is …
Acetylsalicylic acid and its metabolite gentisic acid may act as adjunctive agents in the treatment of psychiatric disorders.
Altinoz MA, Ozpinar A. Altinoz MA, et al. Behav Pharmacol. 2019 Dec;30(8):627-641. doi: 10.1097/FBP.0000000000000517. Behav Pharmacol. 2019. PMID: 31703028 Review.
In parallel to this new concept, recent investigations indicate that adjunction of acetylsalicylic acid (ASA) to the orthodox psychiatric treatments augments therapeutic efficacy in bipolar disorder and schizophrenia. Gentisic acid is a redox active quinonoid ASA me …
In parallel to this new concept, recent investigations indicate that adjunction of acetylsalicylic acid (ASA) to the orthodox psychiatric tr …
Hydroxybenzoic acid isomers and the cardiovascular system.
Juurlink BH, Azouz HJ, Aldalati AM, AlTinawi BM, Ganguly P. Juurlink BH, et al. Nutr J. 2014 Jun 19;13:63. doi: 10.1186/1475-2891-13-63. Nutr J. 2014. PMID: 24943896 Free PMC article. Review.
The compounds focused upon include 2,3-dihydroxybenzoic acid (Pyrocatechuic acid), 2,5-dihydroxybenzoic acid (Gentisic acid), 3,4-dihydroxybenzoic acid (Protocatechuic acid), 3,5-dihydroxybenzoic acid (alpha-Resorcylic acid) and 3-monohyd …
The compounds focused upon include 2,3-dihydroxybenzoic acid (Pyrocatechuic acid), 2,5-dihydroxybenzoic acid ( …
A review on gentisic acid as a plant derived phenolic acid and metabolite of aspirin: Comprehensive pharmacology, toxicology, and some pharmaceutical aspects.
Abedi F, Razavi BM, Hosseinzadeh H. Abedi F, et al. Phytother Res. 2020 Apr;34(4):729-741. doi: 10.1002/ptr.6573. Epub 2019 Dec 11. Phytother Res. 2020. PMID: 31825145 Review.
Beneficial therapeutic effects of phenolic acids have been proven in various research projects including in vivo and in vitro studies. Gentisic acid (GA) is a phenolic acid that has been associated with useful effects on human health, such as antiinflammatory, antig …
Beneficial therapeutic effects of phenolic acids have been proven in various research projects including in vivo and in vitro studies. Ge …
Surface complexation of 2,5-dihydroxybenzoic acid (gentisic acid) at the nanosized hematite-water interface: an ATR-FTIR study and modeling approach.
Hanna K, Quilès F. Hanna K, et al. Langmuir. 2011 Mar 15;27(6):2492-500. doi: 10.1021/la104239x. Epub 2011 Feb 18. Langmuir. 2011. PMID: 21332169
In this study, characteristic interactions of 2,5-dihydroxybenzoic acid (or gentisic acid, GA) with the surface of 15-nm-sized hematite (alpha-Fe2O3) were studied by combining batch macroscopic experiments, in situ attenuated total reflec …
In this study, characteristic interactions of 2,5-dihydroxybenzoic acid (or gentisic acid, GA) wit …
Do Aspirin and Flavonoids Prevent Cancer through a Common Mechanism Involving Hydroxybenzoic Acids?-The Metabolite Hypothesis.
Sankaranarayanan R, Kumar DR, Patel J, Bhat GJ. Sankaranarayanan R, et al. Molecules. 2020 May 10;25(9):2243. doi: 10.3390/molecules25092243. Molecules. 2020. PMID: 32397626 Free PMC article. Review.
Recent reports have demonstrated that the aspirin metabolites 2,3-dihydroxybenzoic acid (2,3-DHBA), 2,5-dihydroxybenzoic acid (2,5-DHBA) and the flavonoid metabolites 2,4,6-trihydroxybenzoic acid (2,4,6-THBA), 3,4-dihydroxybenzoic acid (3,4-DHBA) and 3 …
Recent reports have demonstrated that the aspirin metabolites 2,3-dihydroxybenzoic acid (2,3-DHBA), 2,5-dihydroxybenzoic …
Gentisic acid mitigates gentamicin-induced nephrotoxicity in rats.
Saeedavi M, Goudarzi M, Fatemi I, Basir Z, Noori SMA, Mehrzadi S. Saeedavi M, et al. Tissue Cell. 2023 Oct;84:102191. doi: 10.1016/j.tice.2023.102191. Epub 2023 Aug 1. Tissue Cell. 2023. PMID: 37556917
The current investigation was considered to evaluate the beneficial effects of gentisic acid (GA) on gentamicin (GEN)-induced nephrotoxicity in rat kidneys through assessment of oxidative stress, inflammatory cytokines, and histopathological changes. ...
The current investigation was considered to evaluate the beneficial effects of gentisic acid (GA) on gentamicin (GEN)-induced …
S5H/DMR6 Encodes a Salicylic Acid 5-Hydroxylase That Fine-Tunes Salicylic Acid Homeostasis.
Zhang Y, Zhao L, Zhao J, Li Y, Wang J, Guo R, Gan S, Liu CJ, Zhang K. Zhang Y, et al. Plant Physiol. 2017 Nov;175(3):1082-1093. doi: 10.1104/pp.17.00695. Epub 2017 Sep 12. Plant Physiol. 2017. PMID: 28899963 Free PMC article.
The phytohormone salicylic acid (SA) plays essential roles in biotic and abiotic responses, plant development, and leaf senescence. 2,5-Dihydroxybenzoic acid (2,5-DHBA or gentisic acid) is one of the most commonly occurring aromatic acids …
The phytohormone salicylic acid (SA) plays essential roles in biotic and abiotic responses, plant development, and leaf senescence. 2 …
1,428 results