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Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study.
Bendapudi PK, Hurwitz S, Fry A, Marques MB, Waldo SW, Li A, Sun L, Upadhyay V, Hamdan A, Brunner AM, Gansner JM, Viswanathan S, Kaufman RM, Uhl L, Stowell CP, Dzik WH, Makar RS. Bendapudi PK, et al. Lancet Haematol. 2017 Apr;4(4):e157-e164. doi: 10.1016/S2352-3026(17)30026-1. Epub 2017 Mar 2. Lancet Haematol. 2017. PMID: 28259520
FINDINGS: 214 patients with thrombotic microangiopathy were included in the derivation cohort. A seven-component clinical prediction tool, termed the PLASMIC score, was developed and found to reliably assess the pretest probability of severe ADAMTS1 …
FINDINGS: 214 patients with thrombotic microangiopathy were included in the derivation cohort. A seven-component clinical prediction …
Validation of PLASMIC score and follow-up data in a cohort of patients with suspected microangiopathies from Southern Italy.
Tiscia GL, Ostuni A, Cascavilla N, Cappucci F, Scalzulli P, Battista C, Abrescia A, Aucella F, Buquicchio C, Brigante M, D'Andrea G, Di Paolo B, Giordano G, Infante B, Piano S, Ranieri P, Tullo L, Grandone E. Tiscia GL, et al. J Thromb Thrombolysis. 2018 Aug;46(2):174-179. doi: 10.1007/s11239-018-1674-6. J Thromb Thrombolysis. 2018. PMID: 29737462
ADAMTS13 testing is time-consuming and unavailable in many hospitals. Recently, a seven-variables score named PLASMIC score, has been developed to stratify acute patients, based on their risk of having a severe ADAMTS13 deficiency. …
ADAMTS13 testing is time-consuming and unavailable in many hospitals. Recently, a seven-variables score named PLASMIC …
External validation of the PLASMIC score: a clinical prediction tool for thrombotic thrombocytopenic purpura diagnosis and treatment.
Li A, Khalighi PR, Wu Q, Garcia DA. Li A, et al. J Thromb Haemost. 2018 Jan;16(1):164-169. doi: 10.1111/jth.13882. Epub 2017 Nov 16. J Thromb Haemost. 2018. PMID: 29064619 Free PMC article.
PLASMIC score predicts ADAMTS-13 deficiency in suspected TTP with high discrimination. ...Results The PLASMIC score model predicted severe ADAMTS-13 deficiency with a c statistic of 0.94 (0.88-0.98). ...
PLASMIC score predicts ADAMTS-13 deficiency in suspected TTP with high discrimination. ...Results The PLASMIC …