21324537 22153347 26797608 33245234 24738976 34827645 28885851 25148533 20800486 21902206 20716024 - Search Results

Year	Number of Results
2010	2
2011	3
2012	1
2014	2
2016	1
2017	1
2020	1
2021	1
2022	0

1

Histamine receptors in the CNS as targets for therapeutic intervention.

Passani MB, Blandina P. Passani MB, et al. Trends Pharmacol Sci. 2011 Apr;32(4):242-9. doi: 10.1016/j.tips.2011.01.003. Epub 2011 Feb 15. Trends Pharmacol Sci. 2011. PMID: 21324537 Review.

2

Lead optimization of 2-(piperidin-3-yl)-1H-benzimidazoles: identification of 2-morpholin- and 2-thiomorpholin-2-yl-1H-benzimidazoles as selective and CNS penetrating H₁-antihistamines for insomnia.

Ravula SB, Yu J, Tran JA, Arellano M, Tucci FC, Moree WJ, Li BF, Petroski RE, Wen J, Malany S, Hoare SR, Madan A, Crowe PD, Beaton G. Ravula SB, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):421-6. doi: 10.1016/j.bmcl.2011.10.115. Epub 2011 Nov 15. Bioorg Med Chem Lett. 2012. PMID: 22153347

3

Computational Analysis of Structure-Based Interactions for Novel H₁-Antihistamines.

Yang Y, Li Y, Pan Y, Wang J, Lin F, Wang C, Zhang S, Yang L. Yang Y, et al. Int J Mol Sci. 2016 Jan 19;17(1):129. doi: 10.3390/ijms17010129. Int J Mol Sci. 2016. PMID: 26797608 Free PMC article.

4

Using Graph Databases to Investigate Trends in Structure-Activity Relationship Networks.

Matter H, Buning C, Stefanescu DD, Ruf S, Hessler G. Matter H, et al. J Chem Inf Model. 2020 Dec 28;60(12):6120-6134. doi: 10.1021/acs.jcim.0c00947. Epub 2020 Nov 27. J Chem Inf Model. 2020. PMID: 33245234

5

Matched molecular pair analysis: significance and the impact of experimental uncertainty.

Kramer C, Fuchs JE, Whitebread S, Gedeck P, Liedl KR. Kramer C, et al. J Med Chem. 2014 May 8;57(9):3786-802. doi: 10.1021/jm500317a. Epub 2014 Apr 16. J Med Chem. 2014. PMID: 24738976

6

Data-Driven Analysis of Fluorination of Ligands of Aminergic G Protein Coupled Receptors.

Pietruś W, Kurczab R, Stumpfe D, Bojarski AJ, Bajorath J. Pietruś W, et al. Biomolecules. 2021 Nov 8;11(11):1647. doi: 10.3390/biom11111647. Biomolecules. 2021. PMID: 34827645 Free PMC article.

7

Pyridine-Directed Asymmetric Hydrogenation of 1,1-Diarylalkenes.

Yang H, Wang E, Yang P, Lv H, Zhang X. Yang H, et al. Org Lett. 2017 Oct 6;19(19):5062-5065. doi: 10.1021/acs.orglett.7b02262. Epub 2017 Sep 8. Org Lett. 2017. PMID: 28885851

8

Experimentally validated HERG pharmacophore models as cardiotoxicity prediction tools.

Kratz JM, Schuster D, Edtbauer M, Saxena P, Mair CE, Kirchebner J, Matuszczak B, Baburin I, Hering S, Rollinger JM. Kratz JM, et al. J Chem Inf Model. 2014 Oct 27;54(10):2887-901. doi: 10.1021/ci5001955. Epub 2014 Sep 18. J Chem Inf Model. 2014. PMID: 25148533

9

Identification of a novel selective H1-antihistamine with optimized pharmacokinetic properties for clinical evaluation in the treatment of insomnia.

Moree WJ, Li BF, Zamani-Kord S, Yu J, Coon T, Huang C, Marinkovic D, Tucci FC, Malany S, Bradbury MJ, Hernandez LM, Wen J, Wang H, Hoare SR, Petroski RE, Jalali K, Yang C, Sacaan A, Madan A, Crowe PD, Beaton G. Moree WJ, et al. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5874-8. doi: 10.1016/j.bmcl.2010.07.117. Epub 2010 Aug 3. Bioorg Med Chem Lett. 2010. PMID: 20800486

10

Synthesis of benzothiophene derivatives by Pd-catalyzed or radical-promoted heterocyclodehydration of 1-(2-mercaptophenyl)-2-yn-1-ols.

Gabriele B, Mancuso R, Lupinacci E, Veltri L, Salerno G, Carfagna C. Gabriele B, et al. J Org Chem. 2011 Oct 21;76(20):8277-86. doi: 10.1021/jo201471k. Epub 2011 Sep 22. J Org Chem. 2011. PMID: 21902206

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