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TLR4 knockout protects mice from radiation-induced thymic lymphoma by downregulation of IL6 and miR-21.
Liu C, Gao F, Li B, Mitchel RE, Liu X, Lin J, Zhao L, Cai J. Liu C, et al. Leukemia. 2011 Sep;25(9):1516-9. doi: 10.1038/leu.2011.113. Epub 2011 May 27. Leukemia. 2011. PMID: 21617699 No abstract available.
MiR-21 plays an important role in radiation induced carcinogenesis in BALB/c mice by directly targeting the tumor suppressor gene Big-h3.
Liu C, Li B, Cheng Y, Lin J, Hao J, Zhang S, Mitchel RE, Sun D, Ni J, Zhao L, Gao F, Cai J. Liu C, et al. Int J Biol Sci. 2011 Apr 1;7(3):347-63. doi: 10.7150/ijbs.7.347. Int J Biol Sci. 2011. PMID: 21494432 Free PMC article.