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Therapeutic gene editing of T cells to correct CTLA-4 insufficiency.
Fox TA, Houghton BC, Petersone L, Waters E, Edner NM, McKenna A, Preham O, Hinze C, Williams C, de Albuquerque AS, Kennedy A, Pesenacker AM, Genovese P, Walker LSK, Burns SO, Sansom DM, Booth C, Morris EC. Fox TA, et al. Sci Transl Med. 2022 Oct 26;14(668):eabn5811. doi: 10.1126/scitranslmed.abn5811. Epub 2022 Oct 26. Sci Transl Med. 2022. PMID: 36288278
A phase 1b open-label dose-finding study of ustekinumab in young adults with type 1 diabetes.
Marwaha AK, Chow S, Pesenacker AM, Cook L, Sun A, Long SA, Yang JHM, Ward-Hartstonge KA, Williams E, Domingo-Vila C, Halani K, Harris KM, Tree TIM, Levings MK, Elliott T, Tan R, Dutz JP. Marwaha AK, et al. Immunother Adv. 2021 Nov 13;2(1):ltab022. doi: 10.1093/immadv/ltab022. eCollection 2022. Immunother Adv. 2021. PMID: 35072168 Free PMC article.