22352945,20117081 - Search Results

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Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding.

Huisman FH, Koon N, Bulloch EM, Baker HM, Baker EN, Squire CJ, Parker EJ. Huisman FH, et al. Biochemistry. 2012 Mar 20;51(11):2289-97. doi: 10.1021/bi201717j. Epub 2012 Mar 6. Biochemistry. 2012. PMID: 22352945

The C-terminal regulatory domain is required for catalysis by Neisseria meningitidis alpha-isopropylmalate synthase.

Huisman FH, Hunter MF, Devenish SR, Gerrard JA, Parker EJ. Huisman FH, et al. Biochem Biophys Res Commun. 2010 Feb 26;393(1):168-73. doi: 10.1016/j.bbrc.2010.01.114. Epub 2010 Feb 1. Biochem Biophys Res Commun. 2010. PMID: 20117081

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