22798753 25736404 16507571 19159235 26367462 16156481 22140537 19415127 32992716 30823664 19114711 17298085 15591316 22723704 26296997 20442493 17668005 19036728 15857382 15341524 15975090 20382452 17401676 32556937 18801744 32804090 17307738 2832082 - Search Results

Year	Number of Results
2004	8
2005	13
2006	7
2007	9
2008	10
2009	8
2010	8
2011	12
2012	8
2013	7
2014	5
2015	5
2016	2
2017	2
2018	1
2019	1
2020	7
2021	2
2022	1
2023	0

1

Chemical Biology, Molecular Mechanism and Clinical Perspective of γ-Secretase Modulators in Alzheimer's Disease.

Bulic B, Ness J, Hahn S, Rennhack A, Jumpertz T, Weggen S. Bulic B, et al. Curr Neuropharmacol. 2011 Dec;9(4):598-622. doi: 10.2174/157015911798376352. Curr Neuropharmacol. 2011. PMID: 22798753 Free PMC article.

2

Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice.

Chu Y, Peng X, Long Z, Wang K, Luo S, Sharma A, He G. Chu Y, et al. Acta Biochim Biophys Sin (Shanghai). 2015 Apr;47(4):258-66. doi: 10.1093/abbs/gmv010. Epub 2015 Mar 2. Acta Biochim Biophys Sin (Shanghai). 2015. PMID: 25736404 Free article.

3

The cytosolic loop of the gamma-secretase component presenilin enhancer 2 protects zebrafish embryos from apoptosis.

Zetterberg H, Campbell WA, Yang HW, Xia W. Zetterberg H, et al. J Biol Chem. 2006 Apr 28;281(17):11933-9. doi: 10.1074/jbc.M512521200. Epub 2006 Feb 28. J Biol Chem. 2006. PMID: 16507571 Free article.

4

Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase.

Winkler E, Hobson S, Fukumori A, Dümpelfeld B, Luebbers T, Baumann K, Haass C, Hopf C, Steiner H. Winkler E, et al. Biochemistry. 2009 Feb 17;48(6):1183-97. doi: 10.1021/bi801204g. Biochemistry. 2009. PMID: 19159235

5

Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase.

Lai YJ, Chang GJ, Yeh YH, Pang JH, Huang CC, Chen WJ. Lai YJ, et al. PLoS One. 2015 Sep 14;10(9):e0137426. doi: 10.1371/journal.pone.0137426. eCollection 2015. PLoS One. 2015. PMID: 26367462 Free PMC article.

6

The link between cholesterol and Alzheimer's disease.

Sjögren M, Blennow K. Sjögren M, et al. World J Biol Psychiatry. 2005;6(2):85-97. doi: 10.1080/15622970510029795. World J Biol Psychiatry. 2005. PMID: 16156481 Review.

7

Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo.

Li T, Li YM, Ahn K, Price DL, Sisodia SS, Wong PC. Li T, et al. PLoS One. 2011;6(11):e28179. doi: 10.1371/journal.pone.0028179. Epub 2011 Nov 29. PLoS One. 2011. PMID: 22140537 Free PMC article.

8

Structural and Functional Determinants of gamma-Secretase, an Intramembrane Protease Implicated in Alzheimer's Disease.

Fraering PC. Fraering PC. Curr Genomics. 2007 Dec;8(8):531-49. doi: 10.2174/138920207783769521. Curr Genomics. 2007. PMID: 19415127 Free PMC article.

9

Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks.

Pizzo P, Basso E, Filadi R, Greotti E, Leparulo A, Pendin D, Redolfi N, Rossini M, Vajente N, Pozzan T, Fasolato C. Pizzo P, et al. Cells. 2020 Sep 25;9(10):2166. doi: 10.3390/cells9102166. Cells. 2020. PMID: 32992716 Free PMC article. Review.

10

Presenilins and γ-Secretase in Membrane Proteostasis.

Oikawa N, Walter J. Oikawa N, et al. Cells. 2019 Mar 1;8(3):209. doi: 10.3390/cells8030209. Cells. 2019. PMID: 30823664 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

Search Page

Search Results