23096707 24865334 17329245 16507571 19958215 17047368 21296884 20929727 16464238 21768116 17148000 19415127 16944319 25565961 19595943 18256384 19007897 24941111 29314153 32142795 23891967 22122073 28287404 16234244 18393798 - Search Results

Year	Number of Results
2005	1
2006	5
2007	4
2008	3
2009	2
2010	1
2011	3
2012	2
2013	2
2014	3
2017	1
2018	1
2020	1
2023	0

1

γ-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis.

Pink AE, Simpson MA, Desai N, Trembath RC, Barker JNW. Pink AE, et al. J Invest Dermatol. 2013 Mar;133(3):601-607. doi: 10.1038/jid.2012.372. Epub 2012 Oct 25. J Invest Dermatol. 2013. PMID: 23096707 Free article. Review.

2

Functional analysis and purification of a Pen-2 fusion protein for γ-secretase structural studies.

Holmes O, Paturi S, Wolfe MS, Selkoe DJ. Holmes O, et al. J Neurochem. 2014 Oct;131(1):94-100. doi: 10.1111/jnc.12772. Epub 2014 Jun 18. J Neurochem. 2014. PMID: 24865334 Free PMC article.

3

Abeta42 overproduction associated with structural changes in the catalytic pore of gamma-secretase: common effects of Pen-2 N-terminal elongation and fenofibrate.

Isoo N, Sato C, Miyashita H, Shinohara M, Takasugi N, Morohashi Y, Tsuji S, Tomita T, Iwatsubo T. Isoo N, et al. J Biol Chem. 2007 Apr 27;282(17):12388-96. doi: 10.1074/jbc.M611549200. Epub 2007 Feb 28. J Biol Chem. 2007. PMID: 17329245 Free article.

4

The cytosolic loop of the gamma-secretase component presenilin enhancer 2 protects zebrafish embryos from apoptosis.

Zetterberg H, Campbell WA, Yang HW, Xia W. Zetterberg H, et al. J Biol Chem. 2006 Apr 28;281(17):11933-9. doi: 10.1074/jbc.M512521200. Epub 2006 Feb 28. J Biol Chem. 2006. PMID: 16507571 Free article.

5

The structure and function of Alzheimer's gamma secretase enzyme complex.

Krishnaswamy S, Verdile G, Groth D, Kanyenda L, Martins RN. Krishnaswamy S, et al. Crit Rev Clin Lab Sci. 2009;46(5-6):282-301. doi: 10.3109/10408360903335821. Crit Rev Clin Lab Sci. 2009. PMID: 19958215 Review.

6

Assembly, trafficking and function of gamma-secretase.

Kaether C, Haass C, Steiner H. Kaether C, et al. Neurodegener Dis. 2006;3(4-5):275-83. doi: 10.1159/000095267. Neurodegener Dis. 2006. PMID: 17047368 Review.

7

Functional and topological analysis of Pen-2, the fourth subunit of the gamma-secretase complex.

Bammens L, Chávez-Gutiérrez L, Tolia A, Zwijsen A, De Strooper B. Bammens L, et al. J Biol Chem. 2011 Apr 8;286(14):12271-82. doi: 10.1074/jbc.M110.216978. Epub 2011 Feb 4. J Biol Chem. 2011. PMID: 21296884 Free PMC article.

8

Gamma-secretase gene mutations in familial acne inversa.

Wang B, Yang W, Wen W, Sun J, Su B, Liu B, Ma D, Lv D, Wen Y, Qu T, Chen M, Sun M, Shen Y, Zhang X. Wang B, et al. Science. 2010 Nov 19;330(6007):1065. doi: 10.1126/science.1196284. Epub 2010 Oct 7. Science. 2010. PMID: 20929727

9

Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss.

Campbell WA, Yang H, Zetterberg H, Baulac S, Sears JA, Liu T, Wong ST, Zhong TP, Xia W. Campbell WA, et al. J Neurochem. 2006 Mar;96(5):1423-40. doi: 10.1111/j.1471-4159.2006.03648.x. Epub 2006 Feb 8. J Neurochem. 2006. PMID: 16464238 Free article.

10

DC2 and keratinocyte-associated protein 2 (KCP2), subunits of the oligosaccharyltransferase complex, are regulators of the gamma-secretase-directed processing of amyloid precursor protein (APP).

Wilson CM, Magnaudeix A, Yardin C, Terro F. Wilson CM, et al. J Biol Chem. 2011 Sep 9;286(36):31080-91. doi: 10.1074/jbc.M111.249748. Epub 2011 Jul 18. J Biol Chem. 2011. PMID: 21768116 Free PMC article.

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