24103387 17325205 27059953 33197761 19159235 25762334 21123562 18243734 17719698 19958468 16805816 20126630 34292306 16371134 33188924 18056412 34987110 18256384 32783388 17668005 19036728 21413990 16376853 20921220 16696577 35396575 18239854 3214603 - Search Results

Year	Number of Results
2005	3
2006	13
2007	6
2008	8
2009	8
2010	9
2011	3
2012	2
2013	6
2014	3
2015	1
2016	1
2017	1
2018	1
2019	1
2020	5
2021	4
2022	3
2023	0

1

The role of APP and BACE1 trafficking in APP processing and amyloid-β generation.

Zhang X, Song W. Zhang X, et al. Alzheimers Res Ther. 2013 Oct 8;5(5):46. doi: 10.1186/alzrt211. eCollection 2013. Alzheimers Res Ther. 2013. PMID: 24103387 Free PMC article. Review.

2

Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway.

Spasic D, Raemaekers T, Dillen K, Declerck I, Baert V, Serneels L, Füllekrug J, Annaert W. Spasic D, et al. J Cell Biol. 2007 Feb 26;176(5):629-40. doi: 10.1083/jcb.200609180. J Cell Biol. 2007. PMID: 17325205 Free PMC article.

3

Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments.

Meckler X, Checler F. Meckler X, et al. J Biol Chem. 2016 Jun 10;291(24):12821-12837. doi: 10.1074/jbc.M115.708297. Epub 2016 Apr 8. J Biol Chem. 2016. PMID: 27059953 Free PMC article.

4

NaoXinTong Capsule ameliorates memory deficit in APP/PS1 mice by regulating inflammatory cytokines.

Wang X, Yin Z, Cao P, Zheng S, Chen Y, Yu M, Liao C, Zhang Z, Duan Y, Han J, Zhang S, Yang X. Wang X, et al. Biomed Pharmacother. 2021 Jan;133:110964. doi: 10.1016/j.biopha.2020.110964. Epub 2020 Nov 13. Biomed Pharmacother. 2021. PMID: 33197761 Free article.

5

Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase.

Winkler E, Hobson S, Fukumori A, Dümpelfeld B, Luebbers T, Baumann K, Haass C, Hopf C, Steiner H. Winkler E, et al. Biochemistry. 2009 Feb 17;48(6):1183-97. doi: 10.1021/bi801204g. Biochemistry. 2009. PMID: 19159235

6

Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process.

Kamp F, Winkler E, Trambauer J, Ebke A, Fluhrer R, Steiner H. Kamp F, et al. Biophys J. 2015 Mar 10;108(5):1229-37. doi: 10.1016/j.bpj.2014.12.045. Biophys J. 2015. PMID: 25762334 Free PMC article.

7

Reduced Alzheimer's disease ß-amyloid deposition in transgenic mice expressing S-palmitoylation-deficient APH1aL and nicastrin.

Meckler X, Roseman J, Das P, Cheng H, Pei S, Keat M, Kassarjian B, Golde TE, Parent AT, Thinakaran G. Meckler X, et al. J Neurosci. 2010 Dec 1;30(48):16160-9. doi: 10.1523/JNEUROSCI.4436-10.2010. J Neurosci. 2010. PMID: 21123562 Free PMC article.

8

B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice.

Fuso A, Nicolia V, Cavallaro RA, Ricceri L, D'Anselmi F, Coluccia P, Calamandrei G, Scarpa S. Fuso A, et al. Mol Cell Neurosci. 2008 Apr;37(4):731-46. doi: 10.1016/j.mcn.2007.12.018. Epub 2008 Jan 3. Mol Cell Neurosci. 2008. PMID: 18243734

9

Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders.

Marks N, Berg MJ. Marks N, et al. Neurochem Int. 2008 Jan;52(1-2):184-215. doi: 10.1016/j.neuint.2007.06.020. Epub 2007 Aug 24. Neurochem Int. 2008. PMID: 17719698 Review.

10

Masking of transmembrane-based retention signals controls ER export of gamma-secretase.

Fassler M, Zocher M, Klare S, de la Fuente AG, Scheuermann J, Capell A, Haass C, Valkova C, Veerappan A, Schneider D, Kaether C. Fassler M, et al. Traffic. 2010 Feb;11(2):250-8. doi: 10.1111/j.1600-0854.2009.01014.x. Epub 2009 Nov 5. Traffic. 2010. PMID: 19958468 Free article.

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