24437575,23341204,21291284,21087925 - Search Results

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Crystal structures of type I dehydroquinate dehydratase in complex with quinate and shikimate suggest a novel mechanism of Schiff base formation.

Light SH, Antanasijevic A, Krishna SN, Caffrey M, Anderson WF, Lavie A. Light SH, et al. Biochemistry. 2014 Feb 11;53(5):872-80. doi: 10.1021/bi4015506. Epub 2014 Jan 31. Biochemistry. 2014. PMID: 24437575 Free PMC article.

Reassessing the type I dehydroquinate dehydratase catalytic triad: kinetic and structural studies of Glu86 mutants.

Light SH, Anderson WF, Lavie A. Light SH, et al. Protein Sci. 2013 Apr;22(4):418-24. doi: 10.1002/pro.2218. Epub 2013 Feb 11. Protein Sci. 2013. PMID: 23341204 Free PMC article.

A conserved surface loop in type I dehydroquinate dehydratases positions an active site arginine and functions in substrate binding.

Light SH, Minasov G, Shuvalova L, Peterson SN, Caffrey M, Anderson WF, Lavie A. Light SH, et al. Biochemistry. 2011 Mar 29;50(12):2357-63. doi: 10.1021/bi102020s. Epub 2011 Feb 21. Biochemistry. 2011. PMID: 21291284 Free PMC article.

Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates.

Light SH, Minasov G, Shuvalova L, Duban ME, Caffrey M, Anderson WF, Lavie A. Light SH, et al. J Biol Chem. 2011 Feb 4;286(5):3531-9. doi: 10.1074/jbc.M110.192831. Epub 2010 Nov 18. J Biol Chem. 2011. PMID: 21087925 Free PMC article.

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