26160155 30054192 32263488 28012859 28740600 26320621 35410469 - Search Results

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Year	Number of Results
2015	2
2016	2
2017	2
2018	1
2022	1

Page 1

Characterization of kappa opioid receptor mediated, dynorphin-stimulated [35S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting.

Zhou L, Stahl EL, Lovell KM, Frankowski KJ, Prisinzano TE, Aubé J, Bohn LM. Zhou L, et al. Neuropharmacology. 2015 Dec;99:131-41. doi: 10.1016/j.neuropharm.2015.07.001. Epub 2015 Jul 6. Neuropharmacology. 2015. PMID: 26160155 Free PMC article.

7β-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues.

Sun HJ, Wang YH, Yuan CM, Kong LH, Xu XJ, Wang YJ, Wu HH, Lin C, Qian YY, Huang HM, Xiao L, Liu X, He Q, Fang SY, Xue DQ, Yang XC, Chen H, Zheng YL, Zheng L, Yu LQ, Xie Q, Fu W, Li W, Liu JG, Qiu ZB, Shao LM. Sun HJ, et al. Bioorg Med Chem. 2018 Aug 7;26(14):4254-4263. doi: 10.1016/j.bmc.2018.07.020. Epub 2018 Jul 24. Bioorg Med Chem. 2018. PMID: 30054192

DHDMIQK(KAP): a novel nano-delivery system of dihydroxyl-tetrahydro-isoquinoline-3-carboxylic acid and KPAK towards the thrombus.

Feng Q , Zhao M , Gan T , Zhu H , Wang Y , Zhao S , Wang Y , Wu J , Peng S . Feng Q , et al. J Mater Chem B. 2016 Sep 28;4(36):5991-6003. doi: 10.1039/c6tb00874g. Epub 2016 Aug 26. J Mater Chem B. 2016. PMID: 32263488

Endogenous Opiates and Behavior: 2015.

Bodnar RJ. Bodnar RJ. Peptides. 2017 Feb;88:126-188. doi: 10.1016/j.peptides.2016.12.004. Epub 2016 Dec 22. Peptides. 2017. PMID: 28012859 Review.

Seeking (and Finding) Biased Ligands of the Kappa Opioid Receptor.

Bohn LM, Aubé J. Bohn LM, et al. ACS Med Chem Lett. 2017 Jul 5;8(7):694-700. doi: 10.1021/acsmedchemlett.7b00224. eCollection 2017 Jul 13. ACS Med Chem Lett. 2017. PMID: 28740600 Free PMC article.

Design, synthesis and biological evaluation of novel tetrahydroisoquinoline derivatives as potential PDE4 inhibitors.

Song G, Zhao D, Hu D, Li Y, Jin H, Cui Z. Song G, et al. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4610-4. doi: 10.1016/j.bmcl.2015.08.043. Epub 2015 Aug 21. Bioorg Med Chem Lett. 2015. PMID: 26320621

Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance.

Ma H, Brust T, Frankowski KJ, Lovell KM, Cameron MD, Bohn LM, Aubé J. Ma H, et al. ACS Chem Neurosci. 2022 Apr 20;13(8):1315-1332. doi: 10.1021/acschemneuro.2c00140. Epub 2022 Apr 11. ACS Chem Neurosci. 2022. PMID: 35410469

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