28083796 30704961 26687613 26858964 29225598 21386826 25541616 32508839 29160099 23601496 22924753 25833958 20657281 22794786 24550919 28888664 23565343 21781258 26454643 19907498 22279442 35248118 28645365 24678652 32832483 25700434 29616042 2177477 - Search Results

Year	Number of Results
2009	2
2010	4
2011	10
2012	8
2013	3
2014	7
2015	7
2016	4
2017	6
2018	3
2019	7
2020	3
2022	2

1

Approaches to Mitigate the Unwanted Immunogenicity of Therapeutic Proteins during Drug Development.

Salazar-Fontana LI, Desai DD, Khan TA, Pillutla RC, Prior S, Ramakrishnan R, Schneider J, Joseph A. Salazar-Fontana LI, et al. AAPS J. 2017 Mar;19(2):377-385. doi: 10.1208/s12248-016-0030-z. Epub 2017 Jan 12. AAPS J. 2017. PMID: 28083796 Review.

2

Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies.

Gardner MR, Fetzer I, Kattenhorn LM, Davis-Gardner ME, Zhou AS, Alfant B, Weber JA, Kondur HR, Martinez-Navio JM, Fuchs SP, Desrosiers RC, Gao G, Lifson JD, Farzan M. Gardner MR, et al. Mol Ther. 2019 Mar 6;27(3):650-660. doi: 10.1016/j.ymthe.2019.01.004. Epub 2019 Jan 12. Mol Ther. 2019. PMID: 30704961 Free PMC article.

3

Tolerogenic nanoparticles to induce immunologic tolerance: Prevention and reversal of FVIII inhibitor formation.

Zhang AH, Rossi RJ, Yoon J, Wang H, Scott DW. Zhang AH, et al. Cell Immunol. 2016 Mar;301:74-81. doi: 10.1016/j.cellimm.2015.11.004. Epub 2015 Dec 11. Cell Immunol. 2016. PMID: 26687613

4

Targeted approaches to induce immune tolerance for Pompe disease therapy.

Doerfler PA, Nayak S, Corti M, Morel L, Herzog RW, Byrne BJ. Doerfler PA, et al. Mol Ther Methods Clin Dev. 2016 Jan 27;3:15053. doi: 10.1038/mtm.2015.53. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 26858964 Free PMC article. Review.

5

Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A.

Sherman A, Biswas M, Herzog RW. Sherman A, et al. Front Immunol. 2017 Nov 24;8:1604. doi: 10.3389/fimmu.2017.01604. eCollection 2017. Front Immunol. 2017. PMID: 29225598 Free PMC article. Review.

6

Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer.

Hoffman BE, Martino AT, Sack BK, Cao O, Liao G, Terhorst C, Herzog RW. Hoffman BE, et al. Mol Ther. 2011 Jul;19(7):1263-72. doi: 10.1038/mt.2011.33. Epub 2011 Mar 8. Mol Ther. 2011. PMID: 21386826 Free PMC article.

7

B-Cell Depletion is Protective Against Anti-AAV Capsid Immune Response: A Human Subject Case Study.

Corti M, Elder M, Falk D, Lawson L, Smith B, Nayak S, Conlon T, Clément N, Erger K, Lavassani E, Green M, Doerfler P, Herzog R, Byrne B. Corti M, et al. Mol Ther Methods Clin Dev. 2014;1:14033-. doi: 10.1038/mtm.2014.33. Mol Ther Methods Clin Dev. 2014. PMID: 25541616 Free PMC article.

8

Development of ImmTOR Tolerogenic Nanoparticles for the Mitigation of Anti-drug Antibodies.

Kishimoto TK. Kishimoto TK. Front Immunol. 2020 May 20;11:969. doi: 10.3389/fimmu.2020.00969. eCollection 2020. Front Immunol. 2020. PMID: 32508839 Free PMC article. Review.

9

Safety of Intradiaphragmatic Delivery of Adeno-Associated Virus-Mediated Alpha-Glucosidase (rAAV1-CMV-hGAA) Gene Therapy in Children Affected by Pompe Disease.

Corti M, Liberati C, Smith BK, Lawson LA, Tuna IS, Conlon TJ, Coleman KE, Islam S, Herzog RW, Fuller DD, Collins SW, Byrne BJ. Corti M, et al. Hum Gene Ther Clin Dev. 2017 Dec;28(4):208-218. doi: 10.1089/humc.2017.146. Hum Gene Ther Clin Dev. 2017. PMID: 29160099 Free PMC article. Clinical Trial.

10

B-Cell depletion and immunomodulation before initiation of enzyme replacement therapy blocks the immune response to acid alpha-glucosidase in infantile-onset Pompe disease.

Elder ME, Nayak S, Collins SW, Lawson LA, Kelley JS, Herzog RW, Modica RF, Lew J, Lawrence RM, Byrne BJ. Elder ME, et al. J Pediatr. 2013 Sep;163(3):847-54.e1. doi: 10.1016/j.jpeds.2013.03.002. Epub 2013 Apr 16. J Pediatr. 2013. PMID: 23601496 Free PMC article. Clinical Trial.

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