28420983 28353283 25284317 25899482 33636387 34914695 33741046 33224433 33053406 32612495 28674978 34004238 32625052 25939886 30464741 30045977 33206398 29385885 27169991 27394417 30872638 28576705 31864390 30837320 28353281 33177079 30582936 3026938 - Search Results

Year	Number of Results
2014	1
2015	3
2016	4
2017	6
2018	5
2019	5
2020	5
2021	5
2022	0

1

Increased Oxidative Stress Markers in Cerebrospinal Fluid from Healthy Subjects with Parkinson's Disease-Associated LRRK2 Gene Mutations.

Loeffler DA, Klaver AC, Coffey MP, Aasly JO, LeWitt PA. Loeffler DA, et al. Front Aging Neurosci. 2017 Apr 3;9:89. doi: 10.3389/fnagi.2017.00089. eCollection 2017. Front Aging Neurosci. 2017. PMID: 28420983 Free PMC article.

2

Regulation of LRRK2 by Phosphatases.

Taymans JM. Taymans JM. Adv Neurobiol. 2017;14:145-160. doi: 10.1007/978-3-319-49969-7_8. Adv Neurobiol. 2017. PMID: 28353283 Review.

3

The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease.

Schapansky J, Nardozzi JD, LaVoie MJ. Schapansky J, et al. Neuroscience. 2015 Aug 27;302:74-88. doi: 10.1016/j.neuroscience.2014.09.049. Epub 2014 Oct 2. Neuroscience. 2015. PMID: 25284317 Free PMC article. Review.

4

Cellular processes associated with LRRK2 function and dysfunction.

Wallings R, Manzoni C, Bandopadhyay R. Wallings R, et al. FEBS J. 2015 Aug;282(15):2806-26. doi: 10.1111/febs.13305. Epub 2015 May 9. FEBS J. 2015. PMID: 25899482 Free PMC article. Review.

5

The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease.

De Miranda BR, Castro SL, Rocha EM, Bodle CR, Johnson KE, Greenamyre JT. De Miranda BR, et al. Neurobiol Dis. 2021 Jun;153:105312. doi: 10.1016/j.nbd.2021.105312. Epub 2021 Feb 23. Neurobiol Dis. 2021. PMID: 33636387 Free PMC article.

6

Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.

Mamais A, Kluss JH, Bonet-Ponce L, Landeck N, Langston RG, Smith N, Beilina A, Kaganovich A, Ghosh MC, Pellegrini L, Kumaran R, Papazoglou I, Heaton GR, Bandopadhyay R, Maio N, Kim C, LaVoie MJ, Gershlick DC, Cookson MR. Mamais A, et al. PLoS Biol. 2021 Dec 16;19(12):e3001480. doi: 10.1371/journal.pbio.3001480. eCollection 2021 Dec. PLoS Biol. 2021. PMID: 34914695 Free PMC article.

7

Preclinical modeling of chronic inhibition of the Parkinson's disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo.

Kluss JH, Mazza MC, Li Y, Manzoni C, Lewis PA, Cookson MR, Mamais A. Kluss JH, et al. Mol Neurodegener. 2021 Mar 19;16(1):17. doi: 10.1186/s13024-021-00441-8. Mol Neurodegener. 2021. PMID: 33741046 Free PMC article.

8

Autophagy and Redox Homeostasis in Parkinson's: A Crucial Balancing Act.

Jimenez-Moreno N, Lane JD. Jimenez-Moreno N, et al. Oxid Med Cell Longev. 2020 Nov 10;2020:8865611. doi: 10.1155/2020/8865611. eCollection 2020. Oxid Med Cell Longev. 2020. PMID: 33224433 Free PMC article. Review.

9

Activation of Lrrk2 and α-Synuclein in substantia nigra, striatum, and cerebellum after chronic exposure to arsenite.

Drobna Z. Drobna Z. Toxicol Appl Pharmacol. 2020 Dec 1;408:115278. doi: 10.1016/j.taap.2020.115278. Epub 2020 Oct 11. Toxicol Appl Pharmacol. 2020. PMID: 33053406

10

LRRK2 Phosphorylation, More Than an Epiphenomenon.

Marchand A, Drouyer M, Sarchione A, Chartier-Harlin MC, Taymans JM. Marchand A, et al. Front Neurosci. 2020 Jun 16;14:527. doi: 10.3389/fnins.2020.00527. eCollection 2020. Front Neurosci. 2020. PMID: 32612495 Free PMC article. Review.

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