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Table representation of search results timeline featuring number of search results per year.

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1939 1
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1979 5
1980 3
1981 8
1982 6
1983 9
1984 9
1985 5
1986 9
1987 8
1988 17
1989 11
1990 7
1991 6
1992 10
1993 8
1994 6
1995 8
1996 9
1997 9
1998 3
1999 10
2000 2
2001 8
2002 2
2004 4
2005 2
2006 6
2007 4
2008 4
2009 1
2010 6
2011 2
2012 4
2014 1
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2016 4
2017 4
2018 8
2019 3
2020 6
2021 2
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246 results
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Page 1
3-Methylxanthine production through biodegradation of theobromine by Aspergillus sydowii PT-2.
Zhou B, Ma C, Zheng C, Xia T, Ma B, Liu X. Zhou B, et al. BMC Microbiol. 2020 Aug 27;20(1):269. doi: 10.1186/s12866-020-01951-z. BMC Microbiol. 2020. PMID: 32854634 Free PMC article.

Particularly, A. sydowii PT-2 and A. tamarii PT-7 could degrade theobromine significantly (p < 0.05) in all given liquid mediums. 3,7-Dimethyluric acid, 3-methylxanthine, 7-methylxanthine, 3-methyluric acid, xanthine, and uric acid were detec

Particularly, A. sydowii PT-2 and A. tamarii PT-7 could degrade theobromine significantly (p < 0.05) in all given liquid mediums. 3

Direct conversion of theophylline to 3-methylxanthine by metabolically engineered E. coli.
Algharrawi KH, Summers RM, Gopishetty S, Subramanian M. Algharrawi KH, et al. Microb Cell Fact. 2015 Dec 21;14:203. doi: 10.1186/s12934-015-0395-1. Microb Cell Fact. 2015. PMID: 26691652 Free PMC article.
Here, we show the first example of direct conversion of theophylline to 3-methylxanthine by a metabolically engineered strain of E. coli. ...Strain pDdA grown in super broth was the most efficient strain; 15 mg/mL cells produced 135 mg/L (0.81 mM) 3-methyl
Here, we show the first example of direct conversion of theophylline to 3-methylxanthine by a metabolically engineered strain …
Serum untargeted metabolomic profile of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern.
Rebholz CM, Lichtenstein AH, Zheng Z, Appel LJ, Coresh J. Rebholz CM, et al. Am J Clin Nutr. 2018 Aug 1;108(2):243-255. doi: 10.1093/ajcn/nqy099. Am J Clin Nutr. 2018. PMID: 29917038 Free PMC article. Clinical Trial.
The 10 most influential metabolites for discriminating between the DASH and control dietary patterns were N-methylproline, stachydrine, tryptophan betaine, theobromine, 7-methylurate, chiro-inositol, 3-methylxanthine, methyl glucopyranoside, beta-cryptoxanthin, and …
The 10 most influential metabolites for discriminating between the DASH and control dietary patterns were N-methylproline, stachydrine, tryp …
Demethylation of theophylline (1,3-dimethylxanthine) to 1-methylxanthine: the first step of an antioxidising cascade.
Santos PM, Silva SA, Justino GC, Vieira AJ. Santos PM, et al. Redox Rep. 2010;15(3):138-44. doi: 10.1179/174329210X12650506623726. Redox Rep. 2010. PMID: 20594417 Free PMC article.
The reaction of theophylline with HO(*) radical, produced by photolytic methods at pH 7, was studied in aqueous solution and the products characterised by HPLC and GC-MS. In addition to the expected 1,3-dimethyluric acid, the formation of 1-methylxanthine and, to a …
The reaction of theophylline with HO(*) radical, produced by photolytic methods at pH 7, was studied in aqueous solution and the products ch …
Kidney toxicity of 3-methylxanthine in the rat.
Sellman R, Klemi PJ. Sellman R, et al. J Appl Toxicol. 1984 Dec;4(6):304-7. doi: 10.1002/jat.2550040605. J Appl Toxicol. 1984. PMID: 6520319
The effects of 3-methylxanthine, the pharmacologically active metabolite of theophylline, on the kidneys of Wistar rats after short-term administration were studied. 3-Methylxanthine was administered in oral doses of 0 (control), 50, 100 and 200 mg per …
The effects of 3-methylxanthine, the pharmacologically active metabolite of theophylline, on the kidneys of Wistar rats after …
Possible involvement of organic anion and cation transporters in renal excretion of xanthine derivatives, 3-methylxanthine and enprofylline.
Nadai M, Kato M, Yoshizumi H, Kimura M, Kurono S, Abe F, Saito H, Hasegawa T. Nadai M, et al. Life Sci. 2007 Sep 22;81(15):1175-82. doi: 10.1016/j.lfs.2007.07.032. Epub 2007 Aug 30. Life Sci. 2007. PMID: 17897683
These results suggest that the renal secretory transport of 3-methylxanthine and enprofylline are mediated by probenecid-, cimetidine- and tetraethylammonium-sensitive transport systems. Uric acid, an organic anion, significantly inhibited the renal secretion of …
These results suggest that the renal secretory transport of 3-methylxanthine and enprofylline are mediated by probenecid-, cim …
Analysis of Supramolecular Complexes of 3-Methylxanthine with Field Asymmetric Waveform Ion Mobility Spectrometry Combined with Mass Spectrometry.
Arthur KL, Eiceman GA, Reynolds JC, Creaser CS. Arthur KL, et al. J Am Soc Mass Spectrom. 2016 May;27(5):800-9. doi: 10.1007/s13361-016-1351-y. Epub 2016 Feb 25. J Am Soc Mass Spectrom. 2016. PMID: 26914231 Free article.
Miniaturised field asymmetric waveform ion mobility spectrometry (FAIMS), combined with mass spectrometry (MS), has been applied to the study of self-assembling, noncovalent supramolecular complexes of 3-methylxanthine (3-MX) in the gas phase. 3-MX for …
Miniaturised field asymmetric waveform ion mobility spectrometry (FAIMS), combined with mass spectrometry (MS), has been applied to the stud …
Isolation, characterization and application of theophylline-degrading Aspergillus fungi.
Zhou B, Ma C, Xia T, Li X, Zheng C, Wu T, Liu X. Zhou B, et al. Microb Cell Fact. 2020 Mar 19;19(1):72. doi: 10.1186/s12934-020-01333-0. Microb Cell Fact. 2020. PMID: 32192512 Free PMC article.

Particularly, A. ustus and A. tamarii could degrade theophylline highly significantly (p < 0.01). 1,3-dimethyluric acid, 3-methylxanthine, 3-methyluric acid, xanthine and uric acid were detected consecutively by HPLC in A. ustus and A. tamarii, resp

Particularly, A. ustus and A. tamarii could degrade theophylline highly significantly (p < 0.01). 1,3-dimethyluric acid, 3-

Identifying metabolomic profiles of inflammatory diets in postmenopausal women.
Tabung FK, Liang L, Huang T, Balasubramanian R, Zhao Y, Chandler PD, Manson JE, Cespedes Feliciano EM, Hayden KM, Van Horn L, Clish CB, Giovannucci EL, Rexrode KM. Tabung FK, et al. Clin Nutr. 2020 May;39(5):1478-1490. doi: 10.1016/j.clnu.2019.06.010. Epub 2019 Jun 17. Clin Nutr. 2020. PMID: 31255351 Free PMC article.
Of these, the following ten were replicated: trigonelline, caffeine, acethylamino-6-amino-3-methyluracil, 7-methylxanthine, 1,7-dimethyluric acid, 3-methylxanthine, C18:3CE, glycine, associated with lower dietary inflammatory potential; whereas C52: …
Of these, the following ten were replicated: trigonelline, caffeine, acethylamino-6-amino-3-methyluracil, 7-methylxanthine, 1, …
Associations between CYP2E1 promoter polymorphisms and plasma 1,3-dimethyluric acid/theophylline ratios.
Yoon Y, Park HD, Park KU, Kim JQ, Chang YS, Song J. Yoon Y, et al. Eur J Clin Pharmacol. 2006 Aug;62(8):627-31. doi: 10.1007/s00228-006-0165-4. Epub 2006 Jul 14. Eur J Clin Pharmacol. 2006. PMID: 16841220 Clinical Trial.
OBJECTIVE: Theophylline is metabolized to 1,3-dimethyluric acid (1,3-DMU), 3-methylxanthine, and 1-methylxanthine by CYP1A2 and partly by CYP2E1. Because 1,3-DMU is the major metabolite of theophylline, the 1,3-DMU/theophylline rat …
OBJECTIVE: Theophylline is metabolized to 1,3-dimethyluric acid (1,3-DMU), 3-methylxanthine, and 1-methylxant
246 results