30026371 30172844 32256311 34194386 32523507 31761667 34914695 33629273 32581693 36085537 33765413 32625052 34495322 32034799 33584263 34250948 32143659 32256606 32365906 34419621 35101134 34680045 32848606 31085616 33805527 30481588 34130867 3515291 - Search Results

Year	Number of Results
2018	7
2019	16
2020	22
2021	22
2022	15
2023	1

1

Mitochondrial abnormalities in Parkinson's disease and Alzheimer's disease: can mitochondria be targeted therapeutically?

Macdonald R, Barnes K, Hastings C, Mortiboys H. Macdonald R, et al. Biochem Soc Trans. 2018 Aug 20;46(4):891-909. doi: 10.1042/BST20170501. Epub 2018 Jul 19. Biochem Soc Trans. 2018. PMID: 30026371 Free article. Review.

2

G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice.

Novello S, Arcuri L, Dovero S, Dutheil N, Shimshek DR, Bezard E, Morari M. Novello S, et al. Neurobiol Dis. 2018 Dec;120:21-33. doi: 10.1016/j.nbd.2018.08.018. Epub 2018 Aug 30. Neurobiol Dis. 2018. PMID: 30172844

3

The Emerging Functions of LRRK2 and Rab GTPases in the Endolysosomal System.

Kuwahara T, Iwatsubo T. Kuwahara T, et al. Front Neurosci. 2020 Mar 18;14:227. doi: 10.3389/fnins.2020.00227. eCollection 2020. Front Neurosci. 2020. PMID: 32256311 Free PMC article. Review.

4

Targeting of Lysosomal Pathway Genes for Parkinson's Disease Modification: Insights From Cellular and Animal Models.

Abe T, Kuwahara T. Abe T, et al. Front Neurol. 2021 Jun 14;12:681369. doi: 10.3389/fneur.2021.681369. eCollection 2021. Front Neurol. 2021. PMID: 34194386 Free PMC article. Review.

5

"LRRK2: Autophagy and Lysosomal Activity".

Madureira M, Connor-Robson N, Wade-Martins R. Madureira M, et al. Front Neurosci. 2020 May 25;14:498. doi: 10.3389/fnins.2020.00498. eCollection 2020. Front Neurosci. 2020. PMID: 32523507 Free PMC article. Review.

6

Autophagy lysosomal pathway dysfunction in Parkinson's disease; evidence from human genetics.

Senkevich K, Gan-Or Z. Senkevich K, et al. Parkinsonism Relat Disord. 2020 Apr;73:60-71. doi: 10.1016/j.parkreldis.2019.11.015. Epub 2019 Nov 17. Parkinsonism Relat Disord. 2020. PMID: 31761667 Review.

7

Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.

Mamais A, Kluss JH, Bonet-Ponce L, Landeck N, Langston RG, Smith N, Beilina A, Kaganovich A, Ghosh MC, Pellegrini L, Kumaran R, Papazoglou I, Heaton GR, Bandopadhyay R, Maio N, Kim C, LaVoie MJ, Gershlick DC, Cookson MR. Mamais A, et al. PLoS Biol. 2021 Dec 16;19(12):e3001480. doi: 10.1371/journal.pbio.3001480. eCollection 2021 Dec. PLoS Biol. 2021. PMID: 34914695 Free PMC article.

8

Parkinson's Disease-Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance.

Streubel-Gallasch L, Giusti V, Sandre M, Tessari I, Plotegher N, Giusto E, Masato A, Iovino L, Battisti I, Arrigoni G, Shimshek D, Greggio E, Tremblay ME, Bubacco L, Erlandsson A, Civiero L. Streubel-Gallasch L, et al. Mol Neurobiol. 2021 Jul;58(7):3119-3140. doi: 10.1007/s12035-021-02327-8. Epub 2021 Feb 24. Mol Neurobiol. 2021. PMID: 33629273 Free PMC article.

9

LRRK2-Related Parkinson's Disease Due to Altered Endolysosomal Biology With Variable Lewy Body Pathology: A Hypothesis.

Rivero-Ríos P, Romo-Lozano M, Fasiczka R, Naaldijk Y, Hilfiker S. Rivero-Ríos P, et al. Front Neurosci. 2020 Jun 4;14:556. doi: 10.3389/fnins.2020.00556. eCollection 2020. Front Neurosci. 2020. PMID: 32581693 Free PMC article. Review.

10

Lysosomal Pathogenesis of Parkinson's Disease: Insights From LRRK2 and GBA1 Rodent Models.

Volta M. Volta M. Neurotherapeutics. 2022 Sep 9. doi: 10.1007/s13311-022-01290-z. Online ahead of print. Neurotherapeutics. 2022. PMID: 36085537 Review.

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