31524376 32628351 19891905 25585916 16765624 30531808 23263789 36675536 20213196 25079374 23868642 21944683 22896851 26433571 27306090 20165905 29063238 31509699 27437085 18622207 29471628 21620787 26491018 31624634 31208525 25458518 23067553 1724115 - Search Results

Year	Number of Results
2006	2
2007	7
2008	14
2009	13
2010	20
2011	14
2012	18
2013	22
2014	24
2015	20
2016	16
2017	12
2018	9
2019	11
2020	8
2021	6
2022	8
2023	1

1

Mitochondrial Glutathione Transferase Zeta 1 Is Inactivated More Rapidly by Dichloroacetate than the Cytosolic Enzyme in Adult and Juvenile Rat Liver.

Smeltz MG, Hu Z, Zhong G, Jahn SC, Rowland-Faux L, Horne LP, Stacpoole PW, James MO. Smeltz MG, et al. Chem Res Toxicol. 2019 Oct 21;32(10):2042-2052. doi: 10.1021/acs.chemrestox.9b00207. Epub 2019 Oct 1. Chem Res Toxicol. 2019. PMID: 31524376 Free PMC article.

2

Loss of metabolic flexibility as a result of overexpression of pyruvate dehydrogenase kinases in muscle, liver and the immune system: Therapeutic targets in metabolic diseases.

Jeon JH, Thoudam T, Choi EJ, Kim MJ, Harris RA, Lee IK. Jeon JH, et al. J Diabetes Investig. 2021 Jan;12(1):21-31. doi: 10.1111/jdi.13345. Epub 2020 Sep 10. J Diabetes Investig. 2021. PMID: 32628351 Free PMC article. Review.

3

A modern approach to the treatment of mitochondrial disease.

Parikh S, Saneto R, Falk MJ, Anselm I, Cohen BH, Haas R, Medicine Society TM. Parikh S, et al. Curr Treat Options Neurol. 2009 Nov;11(6):414-30. doi: 10.1007/s11940-009-0046-0. Curr Treat Options Neurol. 2009. PMID: 19891905 Free PMC article.

4

A potent tumoricidal co-drug 'Bet-CA'--an ester derivative of betulinic acid and dichloroacetate selectively and synergistically kills cancer cells.

Saha S, Ghosh M, Dutta SK. Saha S, et al. Sci Rep. 2015 Jan 14;5:7762. doi: 10.1038/srep07762. Sci Rep. 2015. PMID: 25585916 Free PMC article.

5

Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate.

Simpson NE, Han Z, Berendzen KM, Sweeney CA, Oca-Cossio JA, Constantinidis I, Stacpoole PW. Simpson NE, et al. Mol Genet Metab. 2006 Sep-Oct;89(1-2):97-105. doi: 10.1016/j.ymgme.2006.04.015. Epub 2006 Jun 12. Mol Genet Metab. 2006. PMID: 16765624

6

Dichloroacetate and Salinomycin Exert a Synergistic Cytotoxic Effect in Colorectal Cancer Cell Lines.

Skeberdytė A, Sarapinienė I, Aleksander-Krasko J, Stankevičius V, Sužiedėlis K, Jarmalaitė S. Skeberdytė A, et al. Sci Rep. 2018 Dec 10;8(1):17744. doi: 10.1038/s41598-018-35815-4. Sci Rep. 2018. PMID: 30531808 Free PMC article.

7

Finding a job for dichloroacetate.

Luft FC. Luft FC. J Mol Med (Berl). 2013 Mar;91(3):329-31. doi: 10.1007/s00109-012-0989-6. J Mol Med (Berl). 2013. PMID: 23263789 No abstract available.

8

DR5 Up-Regulation Induced by Dichloroacetate Sensitizes Tumor Cells to Lipid Nanoparticles Decorated with TRAIL.

Marco-Brualla J, de Miguel D, Martínez-Lostao L, Anel A. Marco-Brualla J, et al. J Clin Med. 2023 Jan 12;12(2):608. doi: 10.3390/jcm12020608. J Clin Med. 2023. PMID: 36675536 Free PMC article.

9

Novel strategy for treatment of pulmonary arterial hypertension: enhancement of apoptosis.

Huang JB, Liu YL, Sun PW, Lv XD, Bo K, Fan XM. Huang JB, et al. Lung. 2010 Jun;188(3):179-89. doi: 10.1007/s00408-010-9233-8. Epub 2010 Mar 6. Lung. 2010. PMID: 20213196 Review.

10

Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children.

Shroads AL, Coats BS, McDonough CW, Langaee T, Stacpoole PW. Shroads AL, et al. J Clin Pharmacol. 2015 Jan;55(1):50-5. doi: 10.1002/jcph.371. Epub 2014 Aug 6. J Clin Pharmacol. 2015. PMID: 25079374 Free PMC article. Clinical Trial.

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