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β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions.
Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, Leapman RD, Matschinsky FM, Doliba NM, Urs NM, Caron MG, Jacobson DA, Caicedo A, Wess J. Zhu L, et al. Nat Commun. 2017 Feb 1;8:14295. doi: 10.1038/ncomms14295. Nat Commun. 2017. PMID: 28145434 Free PMC article.
Allostery in Drug Development.
Cheng X, Jiang H. Cheng X, et al. Adv Exp Med Biol. 2019;1163:1-23. doi: 10.1007/978-981-13-8719-7_1. Adv Exp Med Biol. 2019. PMID: 31707697 Review.
β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors.
Slosky LM, Bai Y, Toth K, Ray C, Rochelle LK, Badea A, Chandrasekhar R, Pogorelov VM, Abraham DM, Atluri N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney P, Yuan H, Li Z, Wetsel WC, Pinkerton AB, Barak LS, Caron MG. Slosky LM, et al. Cell. 2020 Jun 11;181(6):1364-1379.e14. doi: 10.1016/j.cell.2020.04.053. Epub 2020 May 28. Cell. 2020. PMID: 32470395 Free PMC article.
91 results