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AEB-071 Ameliorates Muscle Weakness by Altering Helper T Lymphocytes in an Experimental Autoimmune Myasthenia Gravis Rat Model.

Jing F, Huang W, Ma Q, Xu SJ, Wu CJ, Guan YX, Chen B. Jing F, et al. Med Sci Monit. 2020 Sep 13;26:e924393. doi: 10.12659/MSM.924393. Med Sci Monit. 2020. PMID: 32920588 Free PMC article.

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Systemic inflammation in asocial BTBR T⁺ tf/J mice predisposes them to increased psoriatic inflammation.

Nadeem A, Ahmad SF, El-Sherbeeny AM, Al-Harbi NO, Bakheet SA, Attia SM. Nadeem A, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Apr 20;83:8-17. doi: 10.1016/j.pnpbp.2017.12.015. Epub 2017 Dec 26. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 29287831

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Extracellular vesicles as potential biomarkers of acute graft-vs-host disease.

Lia G, Brunello L, Bruno S, Carpanetto A, Omedè P, Festuccia M, Tosti L, Maffini E, Giaccone L, Arpinati M, Ciccone G, Boccadoro M, Evangelista A, Camussi G, Bruno B. Lia G, et al. Leukemia. 2018 Mar;32(3):765-773. doi: 10.1038/leu.2017.277. Epub 2017 Aug 30. Leukemia. 2018. PMID: 28852198 Free article.

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Protective Effect of Thalidomide on 2,4,6-Trinitrobenzenesulfonic Acid-Induced Experimental Colitis in Rats via the Inhibition of T Helper 17 Cells.

Xie Y, Li D, Luan X, Jin S, Yan B, Tian F. Xie Y, et al. Can J Gastroenterol Hepatol. 2020 Jul 20;2020:8861854. doi: 10.1155/2020/8861854. eCollection 2020. Can J Gastroenterol Hepatol. 2020. PMID: 32766176 Free PMC article.

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Arthritis risk with immune checkpoint inhibitor therapy for cancer.

Pundole X, Abdel-Wahab N, Suarez-Almazor ME. Pundole X, et al. Curr Opin Rheumatol. 2019 May;31(3):293-299. doi: 10.1097/BOR.0000000000000601. Curr Opin Rheumatol. 2019. PMID: 30870217 Review.

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Targeting Th17 Cells with Small Molecules and Small Interference RNA.

Lin H, Song P, Zhao Y, Xue LJ, Liu Y, Chu CQ. Lin H, et al. Mediators Inflamm. 2015;2015:290657. doi: 10.1155/2015/290657. Epub 2015 Dec 17. Mediators Inflamm. 2015. PMID: 26792955 Free PMC article. Review.

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Inhibitory effects of propofol on Th17 cell differentiation.

Lin CC, Chen DY, Tang KT, Chao YH, Shen CH, Lui PW. Lin CC, et al. Immunopharmacol Immunotoxicol. 2017 Aug;39(4):211-218. doi: 10.1080/08923973.2017.1327962. Epub 2017 May 30. Immunopharmacol Immunotoxicol. 2017. PMID: 28555509

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Are Th17 cells and their cytokines a therapeutic target in Guillain-Barré syndrome?

Wu X, Wang J, Liu K, Zhu J, Zhang HL. Wu X, et al. Expert Opin Ther Targets. 2016;20(2):209-22. doi: 10.1517/14728222.2016.1086751. Epub 2015 Sep 10. Expert Opin Ther Targets. 2016. PMID: 26357850 Review.

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Ubiquitination of RORγt at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment.

He Z, Wang F, Ma J, Sen S, Zhang J, Gwack Y, Zhou Y, Sun Z. He Z, et al. J Immunol. 2016 Aug 15;197(4):1148-58. doi: 10.4049/jimmunol.1600548. Epub 2016 Jul 18. J Immunol. 2016. PMID: 27430721 Free PMC article.

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Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist.

Fauber BP, René O, Deng Y, DeVoss J, Eidenschenk C, Everett C, Ganguli A, Gobbi A, Hawkins J, Johnson AR, La H, Lesch J, Lockey P, Norman M, Ouyang W, Summerhill S, Wong H. Fauber BP, et al. J Med Chem. 2015 Jul 9;58(13):5308-22. doi: 10.1021/acs.jmedchem.5b00597. Epub 2015 Jun 23. J Med Chem. 2015. PMID: 26061388

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