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Page 1
Hybrid immunity-based induction of durable pan-endemic-coronavirus immunity in the elderly.
Loyal L, Braun J, Reimer U, Meyer-Arndt L, Henze L, Kruse B, Dingeldey M, Mangold M, Behrens J, Tober Lau P, Michel J, Grossegesse M, Schnatbaum K, Wenschuh H, Johannis W, Di Cristanziano V, Nitsche A, Klein F, Sander LE, Thiel A. Loyal L, et al. Among authors: klein f. Cell Rep. 2025 Feb 25;44(2):115314. doi: 10.1016/j.celrep.2025.115314. Epub 2025 Feb 16. Cell Rep. 2025. PMID: 39960834 Free article.
Comparison of immune responses to SARS-CoV-2 spike following Omicron infection or Omicron BA.4/5 vaccination in kidney transplant recipients.
Tometten I, Brandt T, Schlotz M, Stumpf R, Landmann S, Kantauskaite M, Lamberti J, Hillebrandt J, Müller L, Kittel M, Ivens K, Gruell H, Voges A, Schaal H, Lübke N, Königshausen E, Rump LC, Klein F, Stegbauer J, Timm J. Tometten I, et al. Among authors: klein f. Front Immunol. 2025 Jan 14;15:1476294. doi: 10.3389/fimmu.2024.1476294. eCollection 2024. Front Immunol. 2025. PMID: 39877366 Free PMC article.
Respiratory syncytial virus infection in patients with haematological diseases: a retrospective multicentre study.
Herrmann S, Graefe S, Christopeit M, Sonnemann P, Hattenhauer T, Mispelbaum R, Monin MB, Orth HM, Flasshove C, Gruell H, Klein F, Klein U, Lehmann C, Naendrup JH, Stemler J, Salmanton-Garcia J, Markus T, Cornely OA, Mellinghoff SC. Herrmann S, et al. Among authors: klein f. Infection. 2024 Dec 17. doi: 10.1007/s15010-024-02449-w. Online ahead of print. Infection. 2024. PMID: 39688808
Tertiary Lymphoid Structures in Pancreatic Cancer are Structurally Homologous, Share Gene Expression Patterns and B-cell Clones with Secondary Lymphoid Organs, but Show Increased T-cell Activation.
Lehmann J, Thelen M, Kreer C, Schran S, Garcia-Marquez MA, Cisic I, Siepmann K, Hagen EM, Eckel HNC, Lohneis P, Kruger S, Boeck S, Ormanns S, Rudelius M, Werner J, Popp F, Klein F, von Bergwelt-Baildon MS, Bruns CJ, Quaas A, Wennhold K, Schlößer HA. Lehmann J, et al. Among authors: klein f. Cancer Immunol Res. 2025 Mar 4;13(3):323-336. doi: 10.1158/2326-6066.CIR-24-0299. Cancer Immunol Res. 2025. PMID: 39661055
Semi-mechanistic population pharmacokinetic modeling of DZIF-10c, a neutralizing antibody against SARS-Cov-2: predicting systemic and lung exposure following inhaled and intravenous administration.
Kurup S, de Mendizabal NV, Becker S, Bolella E, De Sousa D, Fätkenheuer G, Gruell H, Klein F, Malin JJ, Schmid U, Korell J. Kurup S, et al. Among authors: klein f. J Pharmacokinet Pharmacodyn. 2024 Dec 5;52(1):3. doi: 10.1007/s10928-024-09947-2. J Pharmacokinet Pharmacodyn. 2024. PMID: 39636474 Free PMC article.
A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation.
Stein SC, Hansen G, Ssebyatika G, Ströh LJ, Ochulor O, Herold E, Schwarzloh B, Mutschall D, Zischke J, Cordes AK, Schneider T, Hinrichs I, Blasczyk R, Kleine-Weber H, Hoffmann M, Klein F, Kaiser FK, Gonzalez-Hernandez M, Armando F, Ciurkiewicz M, Beythien G, Pöhlmann S, Baumgärtner W, Osterhaus A, Schulz TF, Krey T. Stein SC, et al. Among authors: klein f. J Virol. 2024 Dec 17;98(12):e0122324. doi: 10.1128/jvi.01223-24. Epub 2024 Nov 4. J Virol. 2024. PMID: 39494911 Free PMC article.
From Gut to Blood: Redistribution of Zonulin in People Living with HIV.
Augustin M, Horn C, Ercanoglu MS, Bondet V, de Silva US, Suarez I, Chon SH, Nierhoff D, Zoufaly A, Wenisch C, Knops E, Heger E, Klein F, Duffy D, Müller-Trutwin M, Lehmann C. Augustin M, et al. Among authors: klein f. Biomedicines. 2024 Oct 11;12(10):2316. doi: 10.3390/biomedicines12102316. Biomedicines. 2024. PMID: 39457626 Free PMC article.
Circulating Tumor DNA Sequencing for Biologic Classification and Individualized Risk Stratification in Patients With Hodgkin Lymphoma.
Heger JM, Mammadova L, Mattlener J, Sobesky S, Cirillo M, Altmüller J, Kirst E, Reinke S, Klapper W, Bröckelmann PJ, Ferdinandus J, Kaul H, Schneider G, Schneider J, Schleifenbaum JK, Ullrich RT, Freihammer M, Awerkiew S, Lohmann M, Klein F, Nürnberg P, Hallek M, Rossi D, Mauz-Körholz C, Gattenlöhner S, Bräuninger A, Borchmann P, von Tresckow B, Borchmann S. Heger JM, et al. Among authors: klein f. J Clin Oncol. 2024 Dec 10;42(35):4218-4230. doi: 10.1200/JCO.23.01867. Epub 2024 Sep 30. J Clin Oncol. 2024. PMID: 39348625
Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis.
Meder L, Orschel CI, Otto CJ, Koker M, Brägelmann J, Ercanoglu MS, Dähling S, Compes A, Selenz C, Nill M, Dietlein F, Florin A, Eich ML, Borchmann S, Odenthal M, Blazquez R, Hilberg F, Klein F, Hallek M, Büttner R, Reinhardt HC, Ullrich RT. Meder L, et al. Among authors: klein f. JCI Insight. 2024 May 22;9(10):e166402. doi: 10.1172/jci.insight.166402. JCI Insight. 2024. PMID: 38775153 Free PMC article.
CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells.
Schreiber S, Dressler LS, Loffredo-Verde E, Asen T, Färber S, Wang W, Groll T, Chakraborty A, Kolbe F, Kreer C, Kosinska AD, Simon S, Urban S, Klein F, Riddell SR, Protzer U. Schreiber S, et al. Among authors: klein f. Front Immunol. 2024 Apr 22;15:1340619. doi: 10.3389/fimmu.2024.1340619. eCollection 2024. Front Immunol. 2024. PMID: 38711498 Free PMC article.
SARS-CoV-2 Test-to-Stay in Daycare.
Dewald F, Steger G, Fish I, Torre-Lage I, Hellriegel C, Milz E, Kolb-Bastigkeit A, Heger E, Fries M, Buess M, Marizy N, Michaelis B, Suárez I, Rubio Quintanares GH, Pirkl M, Aigner A, Oberste M, Hellmich M, Wong A, Orduz JC, Fätkenheuer G, Dötsch J, Kossow A, Moench EM, Quade G, Neumann U, Kaiser R, Schranz M, Klein F. Dewald F, et al. Among authors: klein f. Pediatrics. 2024 May 1;153(5):e2023064668. doi: 10.1542/peds.2023-064668. Pediatrics. 2024. PMID: 38596855
Hybrid immunity to SARS-CoV-2 in patients with chronic lymphocytic leukemia.
Mellinghoff SC, Robrecht S, Sprute R, Mayer L, Weskamm LM, Dahlke C, Gruell H, Teipel F, Schlößer HA, Siepmann K, Thelen M, Fink AM, Fischer K, Klein F, Addo MM, Kolovou A, Cornely OA, Eichhorst B, Hallek M, Langerbeins P. Mellinghoff SC, et al. Among authors: klein f. Eur J Haematol. 2024 May;112(5):788-793. doi: 10.1111/ejh.14170. Epub 2024 Feb 4. Eur J Haematol. 2024. PMID: 38311570
Torque Teno Virus Load Is Associated With Centers for Disease Control and Prevention Stage and CD4+ Cell Count in People Living With Human Immunodeficiency Virus but Seems Unrelated to AIDS-Defining Events and Human Pegivirus Load.
Esser PL, Quintanares GHR, Langhans B, Heger E, Böhm M, Jensen BOLE, Esser S, Lübke N, Fätkenheuer G, Lengauer T, Klein F, Oette M, Rockstroh JK, Boesecke C, Di Cristanziano V, Kaiser R, Pirkl M. Esser PL, et al. Among authors: klein f. J Infect Dis. 2024 Aug 16;230(2):e437-e446. doi: 10.1093/infdis/jiae014. J Infect Dis. 2024. PMID: 38230877 Free PMC article.
Five-year single-center analysis of cytomegalovirus viremia in kidney transplant recipients and possible implication for novel prophylactic therapy approaches.
Trappe M, Affeldt P, Grundmann F, Kann M, Koehler FC, Müller RU, Stippel D, Kaiser R, Knops E, Heger E, Steger G, Klein F, Kurschat C, Di Cristanziano V. Trappe M, et al. Among authors: klein f. Transpl Infect Dis. 2024 Feb;26(1):e14233. doi: 10.1111/tid.14233. Epub 2024 Jan 5. Transpl Infect Dis. 2024. PMID: 38180168
Neutralizing response against SARS-CoV-2 Omicron BA.5 and XBB.1.5 in hemodialysis patients.
Affeldt P, Brensing KA, Heger E, Wirtz M, Steger G, Koehler FC, Benzing T, Stippel D, Klein F, Kurschat C, Müller RU, Di Cristanziano V. Affeldt P, et al. Among authors: klein f. Clin Kidney J. 2023 Sep 12;16(12):2757-2759. doi: 10.1093/ckj/sfad230. eCollection 2023 Dec. Clin Kidney J. 2023. PMID: 38046037 Free PMC article. No abstract available.
Bridging the gap - estimation of 2022/2023 SARS-CoV-2 healthcare burden in Germany based on multidimensional data from a rapid epidemic panel.
Harries M, Jaeger VK, Rodiah I, Hassenstein MJ, Ortmann J, Dreier M, von Holt I, Brinkmann M, Dulovic A, Gornyk D, Hovardovska O, Kuczewski C, Kurosinski MA, Schlotz M, Schneiderhan-Marra N, Strengert M, Krause G, Sester M, Klein F, Petersmann A, Karch A, Lange B. Harries M, et al. Among authors: klein f. Int J Infect Dis. 2024 Feb;139:50-58. doi: 10.1016/j.ijid.2023.11.014. Epub 2023 Nov 24. Int J Infect Dis. 2024. PMID: 38008353 Free article.
Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Zehner M, Alt M, Ashurov A, Goldsmith JA, Spies R, Weiler N, Lerma J, Gieselmann L, Stöhr D, Gruell H, Schultz EP, Kreer C, Schlachter L, Janicki H, Laib Sampaio K, Stegmann C, Nemetchek MD, Dähling S, Ullrich L, Dittmer U, Witzke O, Koch M, Ryckman BJ, Lotfi R, McLellan JS, Krawczyk A, Sinzger C, Klein F. Zehner M, et al. Among authors: klein f. Immunity. 2023 Nov 14;56(11):2602-2620.e10. doi: 10.1016/j.immuni.2023.10.009. Immunity. 2023. PMID: 37967532 Free article.
Dynamics and durability of HIV-1 neutralization are determined by viral replication.
Schommers P, Kim DS, Schlotz M, Kreer C, Eggeling R, Hake A, Stecher M, Park J, Radford CE, Dingens AS, Ercanoglu MS, Gruell H, Odidika S, Dahlhaus M, Gieselmann L, Ahmadov E, Lawong RY, Heger E, Knops E, Wyen C, Kümmerle T, Römer K, Scholten S, Wolf T, Stephan C, Suárez I, Raju N, Adhikari A, Esser S, Streeck H, Duerr R, Nanfack AJ, Zolla-Pazner S, Geldmacher C, Geisenberger O, Kroidl A, William W, Maganga L, Ntinginya NE, Georgiev IS, Vehreschild JJ, Hoelscher M, Fätkenheuer G, Lavinder JJ, Bloom JD, Seaman MS, Lehmann C, Pfeifer N, Georgiou G, Klein F. Schommers P, et al. Among authors: klein f. Nat Med. 2023 Nov;29(11):2763-2774. doi: 10.1038/s41591-023-02582-3. Epub 2023 Nov 13. Nat Med. 2023. PMID: 37957379 Free PMC article.
Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa.
Simonis A, Kreer C, Albus A, Rox K, Yuan B, Holzmann D, Wilms JA, Zuber S, Kottege L, Winter S, Meyer M, Schmitt K, Gruell H, Theobald SJ, Hellmann AM, Meyer C, Ercanoglu MS, Cramer N, Munder A, Hallek M, Fätkenheuer G, Koch M, Seifert H, Rietschel E, Marlovits TC, van Koningsbruggen-Rietschel S, Klein F, Rybniker J. Simonis A, et al. Among authors: klein f. Cell. 2023 Nov 9;186(23):5098-5113.e19. doi: 10.1016/j.cell.2023.10.002. Epub 2023 Nov 1. Cell. 2023. PMID: 37918395 Free article.
The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm.
Hamdorf M, Imhof T, Bailey-Elkin B, Betz J, Theobald SJ, Simonis A, Di Cristanziano V, Gieselmann L, Dewald F, Lehmann C, Augustin M, Klein F, Alejandre Alcazar MA, Rongisch R, Fabri M, Rybniker J, Goebel H, Stetefeld J, Brachvogel B, Cursiefen C, Koch M, Bock F. Hamdorf M, et al. Among authors: klein f. J Mol Cell Biol. 2024 Apr 4;15(10):mjad062. doi: 10.1093/jmcb/mjad062. J Mol Cell Biol. 2024. PMID: 37891014 Free PMC article.
15-month post-COVID syndrome in outpatients: Attributes, risk factors, outcomes, and vaccination status - longitudinal, observational, case-control study.
Augustin M, Stecher M, Wüstenberg H, Di Cristanziano V, Sandaradura de Silva U, Picard LK, Pracht E, Rauschning D, Gruell H, Klein F, Wenisch C, Hallek M, Schommers P, Lehmann C. Augustin M, et al. Among authors: klein f. Front Immunol. 2023 Sep 12;14:1226622. doi: 10.3389/fimmu.2023.1226622. eCollection 2023. Front Immunol. 2023. PMID: 37781408 Free PMC article.
Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection.
Harms M, Smith N, Han M, Groß R, von Maltitz P, Stürzel C, Ruiz-Blanco YB, Almeida-Hernández Y, Rodriguez-Alfonso A, Cathelin D, Caspar B, Tahar B, Sayettat S, Bekaddour N, Vanshylla K, Kleipass F, Wiese S, Ständker L, Klein F, Lagane B, Boonen A, Schols D, Benichou S, Sanchez-Garcia E, Herbeuval JP, Münch J. Harms M, et al. Among authors: klein f. Sci Adv. 2023 Jul 7;9(27):eadf8251. doi: 10.1126/sciadv.adf8251. Epub 2023 Jul 5. Sci Adv. 2023. PMID: 37406129 Free PMC article.
Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion.
Eser TM, Baranov O, Huth M, Ahmed MIM, Deák F, Held K, Lin L, Pekayvaz K, Leunig A, Nicolai L, Pollakis G, Buggert M, Price DA, Rubio-Acero R, Reich J, Falk P, Markgraf A, Puchinger K, Castelletti N, Olbrich L, Vanshylla K, Klein F, Wieser A, Hasenauer J, Kroidl I, Hoelscher M, Geldmacher C. Eser TM, et al. Among authors: klein f. Nat Commun. 2023 May 24;14(1):2952. doi: 10.1038/s41467-023-38020-8. Nat Commun. 2023. PMID: 37225706 Free PMC article.
Impaired humoral immunity to BQ.1.1 in convalescent and vaccinated patients.
Dewald F, Pirkl M, Paluschinski M, Kühn J, Elsner C, Schulte B, Knüfer J, Ahmadov E, Schlotz M, Oral G, Bernhard M, Michael M, Luxenburger M, Andrée M, Hennies MT, Hafezi W, Müller MM, Kümpers P, Risse J, Kill C, Manegold RK, von Frantzki U, Richter E, Emmert D, Monzon-Posadas WO, Gräff I, Kogej M, Büning A, Baum M, Teipel F, Mochtarzadeh B, Wolff M, Gruell H, Di Cristanziano V, Burst V, Streeck H, Dittmer U, Ludwig S, Timm J, Klein F. Dewald F, et al. Among authors: klein f. Nat Commun. 2023 May 19;14(1):2835. doi: 10.1038/s41467-023-38127-y. Nat Commun. 2023. PMID: 37208323 Free PMC article. Clinical Trial.
Immunological fingerprint in coronavirus disease-19 convalescents with and without post-COVID syndrome.
Augustin M, Heyn F, Ullrich S, Sandaradura de Silva U, Albert MC, Linne V, Schlotz M, Schommers P, Pracht E, Horn C, Suarez I, Simonis A, Picard LK, Zoufaly A, Wenisch C, Fätkenheuer G, Gruell H, Klein F, Hallek M, Walczak H, Rybniker J, Theobald SJ, Lehmann C. Augustin M, et al. Among authors: klein f. Front Med (Lausanne). 2023 Apr 24;10:1129288. doi: 10.3389/fmed.2023.1129288. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37168268 Free PMC article.
Early intervention with azelastine nasal spray may reduce viral load in SARS-CoV-2 infected patients.
Klussmann JP, Grosheva M, Meiser P, Lehmann C, Nagy E, Szijártó V, Nagy G, Konrat R, Flegel M, Holzer F, Groß D, Steinmetz C, Scherer B, Gruell H, Schlotz M, Klein F, de Aragão PA, Morr H, Al Saleh H, Bilstein A, Russo B, Müller-Scholtz S, Acikel C, Sahin H, Werkhäuser N, Allekotte S, Mösges R. Klussmann JP, et al. Among authors: klein f. Sci Rep. 2023 Apr 26;13(1):6839. doi: 10.1038/s41598-023-32546-z. Sci Rep. 2023. PMID: 37100830 Free PMC article. Clinical Trial.
Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning.
Radford CE, Schommers P, Gieselmann L, Crawford KHD, Dadonaite B, Yu TC, Dingens AS, Overbaugh J, Klein F, Bloom JD. Radford CE, et al. Among authors: klein f. bioRxiv [Preprint]. 2023 Mar 24:2023.03.23.533993. doi: 10.1101/2023.03.23.533993. bioRxiv. 2023. Update in: Cell Host Microbe. 2023 Jul 12;31(7):1200-1215.e9. doi: 10.1016/j.chom.2023.05.025. PMID: 36993197 Free PMC article. Updated. Preprint.
Short- and long-term T cell and antibody responses following dexamethasone treatment in COVID-19.
Thibeault C, Bardtke L, Vanshylla K, di Cristanziano V, Eberhardt KA, Stubbemann P, Hillus D, Tober-Lau P, Mukherjee P, Münn F, Lippert LJ, Helbig ET, Lingscheid T, Steinbeis F, Mittermaier M, Witzenrath M, Zoller T; Pa-COVID study group; Klein F, Sander LE, Kurth F. Thibeault C, et al. Among authors: klein f. JCI Insight. 2023 Apr 24;8(8):e166711. doi: 10.1172/jci.insight.166711. JCI Insight. 2023. PMID: 36881474 Free PMC article.
In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation.
Jensen BO, Knops E, Cords L, Lübke N, Salgado M, Busman-Sahay K, Estes JD, Huyveneers LEP, Perdomo-Celis F, Wittner M, Gálvez C, Mummert C, Passaes C, Eberhard JM, Münk C, Hauber I, Hauber J, Heger E, De Clercq J, Vandekerckhove L, Bergmann S, Dunay GA, Klein F, Häussinger D, Fischer JC, Nachtkamp K, Timm J, Kaiser R, Harrer T, Luedde T, Nijhuis M, Sáez-Cirión A, Schulze Zur Wiesch J, Wensing AMJ, Martinez-Picado J, Kobbe G. Jensen BO, et al. Among authors: klein f. Nat Med. 2023 Mar;29(3):583-587. doi: 10.1038/s41591-023-02213-x. Epub 2023 Feb 20. Nat Med. 2023. PMID: 36807684 Free PMC article.
Boosting compromised SARS-CoV-2-specific immunity with mRNA vaccination in liver transplant recipients.
Luxenburger H, Reeg DB, Lang-Meli J, Reinscheid M, Eisner M, Bettinger D, Oberhardt V, Salimi Alizei E, Wild K, Graeser A, Karl V, Sagar, Emmerich F, Klein F, Panning M, Huzly D, Bengsch B, Boettler T, Elling R, Thimme R, Hofmann M, Neumann-Haefelin C. Luxenburger H, et al. Among authors: klein f. J Hepatol. 2023 May;78(5):1017-1027. doi: 10.1016/j.jhep.2023.02.007. Epub 2023 Feb 18. J Hepatol. 2023. PMID: 36804404 Free PMC article.
Primary ChAdOx1 vaccination does not reactivate pre-existing, cross-reactive immunity.
Henze L, Braun J, Meyer-Arndt L, Jürchott K, Schlotz M, Michel J, Grossegesse M, Mangold M, Dingeldey M, Kruse B, Holenya P, Mages N, Reimer U, Eckey M, Schnatbaum K, Wenschuh H, Timmermann B, Klein F, Nitsche A, Giesecke-Thiel C, Loyal L, Thiel A. Henze L, et al. Among authors: klein f. Front Immunol. 2023 Jan 31;14:1056525. doi: 10.3389/fimmu.2023.1056525. eCollection 2023. Front Immunol. 2023. PMID: 36798117 Free PMC article.
Results of the Cologne Corona Surveillance (CoCoS) study - a cross-sectional study: survey data on risk factors of SARS-CoV-2 infection in adults.
Oberste M, Schnörch N, Shah-Hosseini K, Asenova T, Dewald F, Lehmann C, Buess M, Fätkenheuer G, Klein F, Rosenberger KD, Kossow A, Neuhann F, Hellmich M. Oberste M, et al. Among authors: klein f. BMC Public Health. 2023 Feb 6;23(1):260. doi: 10.1186/s12889-023-15047-6. BMC Public Health. 2023. PMID: 36747171 Free PMC article.
Immune Response to Third and Fourth COVID-19 Vaccination in Hemodialysis Patients and Kidney Transplant Recipients.
Affeldt P, Koehler FC, Brensing KA, Gies M, Platen E, Adam V, Butt L, Grundmann F, Heger E, Hinrichs S, Kalisch N, Oehm S, Steger G, Wirtz M, Benzing T, Stippel D, Klein F, Kurschat C, Müller RU, Di Cristanziano V. Affeldt P, et al. Among authors: klein f. Viruses. 2022 Nov 26;14(12):2646. doi: 10.3390/v14122646. Viruses. 2022. PMID: 36560648 Free PMC article.
COVID-19 and Homelessness: Low Vaccination Rate, High Prevalence.
Oette M, Corpora S, Laudenberg M, Bewermeier F, Kaiser R, Klein F, Heger E. Oette M, et al. Among authors: klein f. Dtsch Arztebl Int. 2022 Sep 5;119(35-36):603-604. doi: 10.3238/arztebl.m2022.0243. Dtsch Arztebl Int. 2022. PMID: 36474338 Free PMC article. No abstract available.
Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination.
Habermann E, Gieselmann L, Tober-Lau P, Klotsche J, Albach FN, Ten Hagen A, Zernicke J, Ahmadov E, Arumahandi de Silva AN, Frommert LM, Kurth F, Sander LE, Burmester GR, Klein F, Biesen R. Habermann E, et al. Among authors: klein f. RMD Open. 2022 Oct;8(2):e002639. doi: 10.1136/rmdopen-2022-002639. RMD Open. 2022. PMID: 36216410 Free PMC article.
Rapid Selection of Sotrovimab Escape Variants in Severe Acute Respiratory Syndrome Coronavirus 2 Omicron-Infected Immunocompromised Patients.
Gliga S, Lübke N, Killer A, Gruell H, Walker A, Dilthey AT, Thielen A, Lohr C, Flaßhove C, Krieg S, Pereira JV, Seraphin TP, Zaufel A, Däumer M, Orth HM, Feldt T, Bode JG, Klein F, Timm J, Luedde T, Jensen BO. Gliga S, et al. Among authors: klein f. Clin Infect Dis. 2023 Feb 8;76(3):408-415. doi: 10.1093/cid/ciac802. Clin Infect Dis. 2023. PMID: 36189631 Free PMC article.
Neutralisation sensitivity of the SARS-CoV-2 omicron BA.2.75 sublineage.
Gruell H, Vanshylla K, Tober-Lau P, Hillus D, Sander LE, Kurth F, Klein F. Gruell H, et al. Among authors: klein f. Lancet Infect Dis. 2022 Oct;22(10):1422-1423. doi: 10.1016/S1473-3099(22)00580-1. Epub 2022 Sep 6. Lancet Infect Dis. 2022. PMID: 36084664 Free PMC article. No abstract available.
A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Barnes CO, Schoofs T, Gnanapragasam PNP, Golijanin J, Huey-Tubman KE, Gruell H, Schommers P, Suh-Toma N, Lee YE, Cetrulo Lorenzi JC, Piechocka-Trocha A, Scheid JF, West AP Jr, Walker BD, Seaman MS, Klein F, Nussenzweig MC, Bjorkman PJ. Barnes CO, et al. Among authors: klein f. Sci Adv. 2022 Aug 12;8(32):eabp8155. doi: 10.1126/sciadv.abp8155. Epub 2022 Aug 12. Sci Adv. 2022. PMID: 35960796 Free PMC article.
SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns.
Gruell H, Vanshylla K, Korenkov M, Tober-Lau P, Zehner M, Münn F, Janicki H, Augustin M, Schommers P, Sander LE, Kurth F, Kreer C, Klein F. Gruell H, et al. Among authors: klein f. Cell Host Microbe. 2022 Sep 14;30(9):1231-1241.e6. doi: 10.1016/j.chom.2022.07.002. Epub 2022 Jul 7. Cell Host Microbe. 2022. PMID: 35921836 Free PMC article.
Viral Load Dynamics in SARS-CoV-2 Omicron Breakthrough Infections.
Dewald F, Detmer S, Pirkl M, Hellmich M, Heger E, Herrmann M, Lehmann C, Zweigner J, Klein F. Dewald F, et al. Among authors: klein f. J Infect Dis. 2022 Nov 11;226(10):1721-1725. doi: 10.1093/infdis/jiac290. J Infect Dis. 2022. PMID: 35906927 Free PMC article.
Results of the Cologne Corona surveillance (CoCoS) study - a prospective population-based cohort study: incidence data and potential underestimation of new SARS-CoV-2 adult infections by health authorities.
Oberste M, Pusch LM, Roth R, Shah-Hosseini K, Schmitz J, Heger E, Dewald F, Müller C, von Goltzheim LS, Lehmann C, Buess M, Wolff A, Fätkenheuer G, Wiesmüller G, Klein F, Rosenberger KD, Neuhann F, Hellmich M. Oberste M, et al. Among authors: klein f. BMC Public Health. 2022 Jul 19;22(1):1379. doi: 10.1186/s12889-022-13745-1. BMC Public Health. 2022. PMID: 35854283 Free PMC article.
Antibody response after COVID-19 vaccination in intravenous immunoglobulin-treated immune neuropathies.
Svačina MKR, Meißner A, Schweitzer F, Ladwig A, Sprenger-Svačina A, Klein I, Wüstenberg H, Kohle F, Schneider C, Grether NB, Wunderlich G, Fink GR, Klein F, Di Cristanziano V, Lehmann HC. Svačina MKR, et al. Among authors: klein f. Eur J Neurol. 2022 Nov;29(11):3380-3388. doi: 10.1111/ene.15508. Epub 2022 Aug 8. Eur J Neurol. 2022. PMID: 35842740 Free PMC article.
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt L, Braun J, Fauchere F, Vanshylla K, Loyal L, Henze L, Kruse B, Dingeldey M, Jürchott K, Mangold M, Maraj A, Braginets A, Böttcher C, Nitsche A, de la Rosa K, Ratswohl C, Sawitzki B, Holenya P, Reimer U, Sander LE, Klein F, Paul F, Bellmann-Strobl J, Thiel A, Giesecke-Thiel C. Meyer-Arndt L, et al. Among authors: klein f. J Neurol Neurosurg Psychiatry. 2022 Sep;93(9):960-971. doi: 10.1136/jnnp-2022-329395. Epub 2022 Jul 14. J Neurol Neurosurg Psychiatry. 2022. PMID: 35835468 Free PMC article.
Implementing the Lolli-Method and pooled RT-qPCR testing for SARS-CoV-2 surveillance in schools: a pilot project.
Kretschmer AC, Junker L, Dewald F, Linne V, Hennen L, Horemheb-Rubio G, Kaiser R, Steger G, Joachim A, Schönenkorb J, Cosgun ZC, Mühlhans N, Heger E, Knops E, Leisse C, Kessel B, Heinsohn T, Rodiah I, Lange B, Ritter AL, Fries M, Kossow A, Nießen J, Dötsch J, Klein F, Rybniker J, Fätkenheuer G, Suárez I. Kretschmer AC, et al. Among authors: klein f. Infection. 2023 Apr;51(2):459-464. doi: 10.1007/s15010-022-01865-0. Epub 2022 Jun 27. Infection. 2023. PMID: 35759174 Free PMC article.
Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children.
Dewald F, Suárez I, Johnen R, Grossbach J, Moran-Tovar R, Steger G, Joachim A, Rubio GH, Fries M, Behr F, Kley J, Lingnau A, Kretschmer A, Gude C, Baeza-Flores G, Del Valle DL, Roblero-Hernandez A, Magana-Cerino J, Hernandez AT, Ruiz-Quinones J, Schega K, Linne V, Junker L, Wunsch M, Heger E, Knops E, Di Cristanziano V, Meyer M, Hünseler C, Weber LT, Lüers JC, Quade G, Wisplinghoff H, Tiemann C, Zotz R, Jomaa H, Pranada A, Herzum I, Cullen P, Schmitz FJ, Philipsen P, Kirchner G, Knabbe C, Hellmich M, Buess M, Wolff A, Kossow A, Niessen J, Jeworutzki S, Schräpler JP, Lässig M, Dötsch J, Fätkenheuer G, Kaiser R, Beyer A, Rybniker J, Klein F. Dewald F, et al. Among authors: klein f. Nat Commun. 2022 Jun 25;13(1):3640. doi: 10.1038/s41467-022-30664-2. Nat Commun. 2022. PMID: 35752615 Free PMC article.
SARS-CoV-2-specific cellular response following third COVID-19 vaccination in patients with chronic lymphocytic leukemia.
Mellinghoff SC, Mayer L, Robrecht S, Weskamm LM, Dahlke C, Gruell H, Schlotz M, Vanshylla K, Schloser HA, Thelen M, Fink AM, Fischer K, Klein F, Addo MM, Eichhorst B, Hallek M, Langerbeins P. Mellinghoff SC, et al. Among authors: klein f. Haematologica. 2022 Oct 1;107(10):2480-2484. doi: 10.3324/haematol.2022.280982. Haematologica. 2022. PMID: 35734927 Free PMC article. No abstract available.
Antibody-mediated neutralization of SARS-CoV-2.
Gruell H, Vanshylla K, Weber T, Barnes CO, Kreer C, Klein F. Gruell H, et al. Among authors: klein f. Immunity. 2022 Jun 14;55(6):925-944. doi: 10.1016/j.immuni.2022.05.005. Epub 2022 May 13. Immunity. 2022. PMID: 35623355 Free PMC article. Review.
Effect of 3BNC117 and romidepsin on the HIV-1 reservoir in people taking suppressive antiretroviral therapy (ROADMAP): a randomised, open-label, phase 2A trial.
Gruell H, Gunst JD, Cohen YZ, Pahus MH, Malin JJ, Platten M, Millard KG, Tolstrup M, Jones RB, Conce Alberto WD, Lorenzi JCC, Oliveira TY, Kümmerle T, Suárez I, Unson-O'Brien C, Nogueira L, Olesen R, Østergaard L, Nielsen H, Lehmann C, Nussenzweig MC, Fätkenheuer G, Klein F, Caskey M, Søgaard OS. Gruell H, et al. Among authors: klein f. Lancet Microbe. 2022 Mar;3(3):e203-e214. doi: 10.1016/S2666-5247(21)00239-1. Epub 2022 Jan 24. Lancet Microbe. 2022. PMID: 35544074 Free PMC article. Clinical Trial.
CXCR3 Expression Pattern on CD4+ T Cells and IP-10 Levels with Regard to the HIV-1 Reservoir in the Gut-Associated Lymphatic Tissue.
Augustin M, Horn C, Ercanoglu MS, Sandaradura de Silva U, Bondet V, Suarez I, Chon SH, Nierhoff D, Knops E, Heger E, Vivaldi C, Schäfer H, Oette M, Fätkenheuer G, Klein F, Duffy D, Müller-Trutwin M, Lehmann C. Augustin M, et al. Among authors: klein f. Pathogens. 2022 Apr 18;11(4):483. doi: 10.3390/pathogens11040483. Pathogens. 2022. PMID: 35456158 Free PMC article.
Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections.
Tober-Lau P, Gruell H, Vanshylla K, Koch WM, Hillus D, Schommers P, Suárez I, Suttorp N, Sander LE, Klein F, Kurth F. Tober-Lau P, et al. Among authors: klein f. Emerg Infect Dis. 2022 May;28(5):1050-1052. doi: 10.3201/eid2805.220271. Epub 2022 Mar 8. Emerg Infect Dis. 2022. PMID: 35259088 Free PMC article.
No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults.
Ercanoglu MS, Gieselmann L, Dähling S, Poopalasingam N, Detmer S, Koch M, Korenkov M, Halwe S, Klüver M, Di Cristanziano V, Janicki H, Schlotz M, Worczinski J, Gathof B, Gruell H, Zehner M, Becker S, Vanshylla K, Kreer C, Klein F. Ercanoglu MS, et al. Among authors: klein f. iScience. 2022 Mar 18;25(3):103951. doi: 10.1016/j.isci.2022.103951. Epub 2022 Feb 19. iScience. 2022. PMID: 35224466 Free PMC article.
Morbidity of Respiratory Syncytial Virus (RSV) Infections: RSV Compared With Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Children Aged 0-4 Years in Cologne, Germany.
Meyer M, Ruebsteck E, Eifinger F, Klein F, Oberthuer A, van Koningsbruggen-Rietschel S, Huenseler C, Weber LT. Meyer M, et al. Among authors: klein f. J Infect Dis. 2022 Dec 13;226(12):2050-2053. doi: 10.1093/infdis/jiac052. J Infect Dis. 2022. PMID: 35172330 Free PMC article.
Immune Responses to SARS-CoV-2 Infection and Vaccination in Dialysis Patients and Kidney Transplant Recipients.
Affeldt P, Koehler FC, Brensing KA, Adam V, Burian J, Butt L, Gies M, Grundmann F, Hinrichs S, Johannis W, Kalisch N, Meyer-Delpho M, Oehm S, Platen E, Schöler C, Heger E, Steger G, Stippel D, Ziegelhöfer A, Benzing T, Klein F, Kurschat C, Müller RU, Cristanziano VD. Affeldt P, et al. Among authors: klein f. Microorganisms. 2021 Dec 21;10(1):4. doi: 10.3390/microorganisms10010004. Microorganisms. 2021. PMID: 35056453 Free PMC article.
Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Weber T, Potthoff J, Bizu S, Labuhn M, Dold L, Schoofs T, Horning M, Ercanoglu MS, Kreer C, Gieselmann L, Vanshylla K, Langhans B, Janicki H, Ströh LJ, Knops E, Nierhoff D, Spengler U, Kaiser R, Bjorkman PJ, Krey T, Bankwitz D, Pfeifer N, Pietschmann T, Flyak AI, Klein F. Weber T, et al. Among authors: klein f. Immunity. 2022 Feb 8;55(2):341-354.e7. doi: 10.1016/j.immuni.2021.12.003. Epub 2022 Jan 5. Immunity. 2022. PMID: 34990590 Free PMC article.
Case Report: Clinical Management of a Patient With Metastatic Non-Small Cell Lung Cancer Newly Receiving Immune Checkpoint Inhibition During Symptomatic COVID-19.
Mellinghoff SC, Vanshylla K, Dahlke C, Addo MM, Cornely OA, Klein F, Persigehl T, Rybniker J, Gruell H, Bröckelmann PJ. Mellinghoff SC, et al. Among authors: klein f. Front Immunol. 2021 Dec 20;12:798276. doi: 10.3389/fimmu.2021.798276. eCollection 2021. Front Immunol. 2021. PMID: 34987520 Free PMC article.
Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers.
Vanshylla K, Fan C, Wunsch M, Poopalasingam N, Meijers M, Kreer C, Kleipass F, Ruchnewitz D, Ercanoglu MS, Gruell H, Münn F, Pohl K, Janicki H, Nolden T, Bartl S, Stein SC, Augustin M, Dewald F, Gieselmann L, Schommers P, Schulz TF, Sander LE, Koch M, Łuksza M, Lässig M, Bjorkman PJ, Klein F. Vanshylla K, et al. Among authors: klein f. Cell Host Microbe. 2022 Jan 12;30(1):69-82.e10. doi: 10.1016/j.chom.2021.12.010. Epub 2021 Dec 18. Cell Host Microbe. 2022. PMID: 34973165 Free PMC article.
SARS-CoV-2 specific cellular response following COVID-19 vaccination in patients with chronic lymphocytic leukemia.
Mellinghoff SC, Robrecht S, Mayer L, Weskamm LM, Dahlke C, Gruell H, Vanshylla K, Schlösser HA, Thelen M, Fink AM, Fischer K, Klein F, Addo MM, Eichhorst B, Hallek M, Langerbeins P. Mellinghoff SC, et al. Among authors: klein f. Leukemia. 2022 Feb;36(2):562-565. doi: 10.1038/s41375-021-01500-1. Epub 2021 Dec 22. Leukemia. 2022. PMID: 34937858 Free PMC article. No abstract available.
SARS-CoV-2-neutralizing antibody treatment in patients with COVID-19 and immunodeficiency due to B-cell non-Hodgkin lymphoma.
Malin JJ, Di Cristanziano V, Horn C, Pracht E, Garcia Borrega J, Heger E, Knops E, Kaiser R, Böll B, Lehmann C, Jung N, Borchmann P, Fätkenheuer G, Klein F, Hallek M, Rybniker J. Malin JJ, et al. Among authors: klein f. Blood Adv. 2022 Mar 8;6(5):1580-1584. doi: 10.1182/bloodadvances.2021006655. Blood Adv. 2022. PMID: 34911078 Free PMC article. No abstract available.
Safe and effective pool testing for SARS-CoV-2 detection.
Wunsch M, Aschemeier D, Heger E, Ehrentraut D, Krüger J, Hufbauer M, Syed AS, Horemheb-Rubio G, Dewald F, Fish I, Schlotz M, Gruell H, Augustin M, Lehmann C, Kaiser R, Knops E, Silling S, Klein F. Wunsch M, et al. Among authors: klein f. J Clin Virol. 2021 Dec;145:105018. doi: 10.1016/j.jcv.2021.105018. Epub 2021 Oct 28. J Clin Virol. 2021. PMID: 34775143 Free PMC article.
SARS-CoV-2 Infection in Fully Vaccinated Individuals of Old Age Strongly Boosts the Humoral Immune Response.
Müller L, Andrée M, Ostermann PN, Jazmati N, Flüh G, Fischer JC, Bölke E, Heger E, Vanshylla K, Klein F, Wisplinghoff H, Schaal H, Drexler I, Walker A, Adams O, Timm J. Müller L, et al. Among authors: klein f. Front Med (Lausanne). 2021 Oct 11;8:746644. doi: 10.3389/fmed.2021.746644. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34708057 Free PMC article.
Long-term immunogenicity of BNT162b2 vaccination in older people and younger health-care workers.
Tober-Lau P, Schwarz T, Vanshylla K, Hillus D, Gruell H; EICOV/COVIM Study Group; Suttorp N, Landgraf I, Kappert K, Seybold J, Drosten C, Klein F, Kurth F, Sander LE, Corman VM. Tober-Lau P, et al. Among authors: klein f. Lancet Respir Med. 2021 Nov;9(11):e104-e105. doi: 10.1016/S2213-2600(21)00456-2. Epub 2021 Oct 20. Lancet Respir Med. 2021. PMID: 34687656 Free PMC article. No abstract available.
Mobile PCR-based surveillance for SARS-CoV-2 to reduce visiting restrictions in nursing homes during the COVID-19 pandemic: a pilot study.
Stemler J, Kramer T, Dimitriou V, Wieland U, Schumacher S, Sprute R, Oberste M, Wiesmüller G, Rau H, Pieper S, Bethe U, Lehmann C, Hellmich M, Klein F, Langebartels G, Cornely OA. Stemler J, et al. Among authors: klein f. Infection. 2022 Jun;50(3):607-616. doi: 10.1007/s15010-021-01716-4. Epub 2021 Oct 20. Infection. 2022. PMID: 34669164 Free PMC article.
Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection.
Halwe S, Kupke A, Vanshylla K, Liberta F, Gruell H, Zehner M, Rohde C, Krähling V, Gellhorn Serra M, Kreer C, Klüver M, Sauerhering L, Schmidt J, Cai Z, Han F, Young D, Yang G, Widera M, Koch M, Werner A, Kämper L, Becker N, Marlow MS, Eickmann M, Ciesek S, Schiele F, Klein F, Becker S. Halwe S, et al. Among authors: klein f. Viruses. 2021 Jul 29;13(8):1498. doi: 10.3390/v13081498. Viruses. 2021. PMID: 34452363 Free PMC article.
Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study.
Hillus D, Schwarz T, Tober-Lau P, Vanshylla K, Hastor H, Thibeault C, Jentzsch S, Helbig ET, Lippert LJ, Tscheak P, Schmidt ML, Riege J, Solarek A, von Kalle C, Dang-Heine C, Gruell H, Kopankiewicz P, Suttorp N, Drosten C, Bias H, Seybold J; EICOV/COVIM Study Group; Klein F, Kurth F, Corman VM, Sander LE. Hillus D, et al. Among authors: klein f. Lancet Respir Med. 2021 Nov;9(11):1255-1265. doi: 10.1016/S2213-2600(21)00357-X. Epub 2021 Aug 13. Lancet Respir Med. 2021. PMID: 34391547 Free PMC article.
Protocol of the Cologne Corona Surveillance (CoCoS) Study- a prospective population-based cohort study.
Oberste M, Pusch LM, Roth R, Shah-Hosseini K, Dewald F, Müller C, Stach von Goltzheim L, Lehmann C, Buess M, Wolff A, Fätkenheuer G, Wiesmüller G, Klein F, Hellmich M, Neuhann F. Oberste M, et al. Among authors: klein f. BMC Public Health. 2021 Jul 2;21(1):1295. doi: 10.1186/s12889-021-11206-9. BMC Public Health. 2021. PMID: 34215236 Free PMC article.
Evaluation of a Rapid Antigen Test To Detect SARS-CoV-2 Infection and Identify Potentially Infectious Individuals.
Korenkov M, Poopalasingam N, Madler M, Vanshylla K, Eggeling R, Wirtz M, Fish I, Dewald F, Gieselmann L, Lehmann C, Fätkenheuer G, Gruell H, Pfeifer N, Heger E, Klein F. Korenkov M, et al. Among authors: klein f. J Clin Microbiol. 2021 Aug 18;59(9):e0089621. doi: 10.1128/JCM.00896-21. Epub 2021 Aug 18. J Clin Microbiol. 2021. PMID: 34213977 Free PMC article.
CD86+ Antigen-Presenting B Cells Are Increased in Cancer, Localize in Tertiary Lymphoid Structures, and Induce Specific T-cell Responses.
Wennhold K, Thelen M, Lehmann J, Schran S, Preugszat E, Garcia-Marquez M, Lechner A, Shimabukuro-Vornhagen A, Ercanoglu MS, Klein F, Thangarajah F, Eidt S, Löser H, Bruns C, Quaas A, von Bergwelt-Baildon M, Schlößer HA. Wennhold K, et al. Among authors: klein f. Cancer Immunol Res. 2021 Sep;9(9):1098-1108. doi: 10.1158/2326-6066.CIR-20-0949. Epub 2021 Jun 21. Cancer Immunol Res. 2021. PMID: 34155067
Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19.
Theobald SJ, Simonis A, Georgomanolis T, Kreer C, Zehner M, Eisfeld HS, Albert MC, Chhen J, Motameny S, Erger F, Fischer J, Malin JJ, Gräb J, Winter S, Pouikli A, David F, Böll B, Koehler P, Vanshylla K, Gruell H, Suárez I, Hallek M, Fätkenheuer G, Jung N, Cornely OA, Lehmann C, Tessarz P, Altmüller J, Nürnberg P, Kashkar H, Klein F, Koch M, Rybniker J. Theobald SJ, et al. Among authors: klein f. EMBO Mol Med. 2021 Aug 9;13(8):e14150. doi: 10.15252/emmm.202114150. Epub 2021 Jun 16. EMBO Mol Med. 2021. PMID: 34133077 Free PMC article.
Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study.
Augustin M, Schommers P, Stecher M, Dewald F, Gieselmann L, Gruell H, Horn C, Vanshylla K, Cristanziano VD, Osebold L, Roventa M, Riaz T, Tschernoster N, Altmueller J, Rose L, Salomon S, Priesner V, Luers JC, Albus C, Rosenkranz S, Gathof B, Fätkenheuer G, Hallek M, Klein F, Suárez I, Lehmann C. Augustin M, et al. Among authors: klein f. Lancet Reg Health Eur. 2021 Jul;6:100122. doi: 10.1016/j.lanepe.2021.100122. Epub 2021 May 18. Lancet Reg Health Eur. 2021. PMID: 34027514 Free PMC article.
Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infection in humans.
Vanshylla K, Di Cristanziano V, Kleipass F, Dewald F, Schommers P, Gieselmann L, Gruell H, Schlotz M, Ercanoglu MS, Stumpf R, Mayer P, Zehner M, Heger E, Johannis W, Horn C, Suárez I, Jung N, Salomon S, Eberhardt KA, Gathof B, Fätkenheuer G, Pfeifer N, Eggeling R, Augustin M, Lehmann C, Klein F. Vanshylla K, et al. Among authors: klein f. Cell Host Microbe. 2021 Jun 9;29(6):917-929.e4. doi: 10.1016/j.chom.2021.04.015. Epub 2021 May 3. Cell Host Microbe. 2021. PMID: 33984285 Free PMC article.
First manifestation of adult-onset Still's disease after COVID-19.
Bamidis AD, Koehler P, di Cristanziano V, Rasche K, Demirel B, Bacher P, Hallek M, Kochanek M, Klein F, Hofmann SC, Wesselmann U, Kofler DM. Bamidis AD, et al. Among authors: klein f. Lancet Rheumatol. 2021 May;3(5):e319-e321. doi: 10.1016/S2665-9913(21)00072-2. Epub 2021 Mar 26. Lancet Rheumatol. 2021. PMID: 33817663 Free PMC article. No abstract available.
Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgG.
Eberhardt KA, Dewald F, Heger E, Gieselmann L, Vanshylla K, Wirtz M, Kleipass F, Johannis W, Schommers P, Gruell H, Brensing KA, Müller RU, Augustin M, Lehmann C, Koch M, Klein F, Di Cristanziano V. Eberhardt KA, et al. Among authors: klein f. Microorganisms. 2021 Mar 31;9(4):733. doi: 10.3390/microorganisms9040733. Microorganisms. 2021. PMID: 33807490 Free PMC article.
CD34T+ Humanized Mouse Model to Study Mucosal HIV-1 Transmission and Prevention.
Vanshylla K, Held K, Eser TM, Gruell H, Kleipass F, Stumpf R, Jain K, Weiland D, Münch J, Grüttner B, Geldmacher C, Klein F. Vanshylla K, et al. Among authors: klein f. Vaccines (Basel). 2021 Feb 27;9(3):198. doi: 10.3390/vaccines9030198. Vaccines (Basel). 2021. PMID: 33673566 Free PMC article.
Correction: Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV.
Theobald SJ, Kreer C, Khailaie S, Bonifacius A, Eiz-Vesper B, Figueiredo C, Mach M, Backovic M, Ballmaier M, Koenig J, Olbrich H, Schneider A, Volk V, Danisch S, Gieselmann L, Ercanoglu MS, Messerle M, von Kaisenberg C, Witte T, Klawonn F, Meyer-Hermann M, Klein F, Stripecke R. Theobald SJ, et al. Among authors: klein f. PLoS Pathog. 2021 Mar 1;17(3):e1009385. doi: 10.1371/journal.ppat.1009385. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33647022 Free PMC article.
Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting.
Müller L, Ostermann PN, Walker A, Wienemann T, Mertens A, Adams O, Andree M, Hauka S, Lübke N, Keitel V, Drexler I, Di Cristanziano V, Hermsen DF, Kaiser R, Boege F, Klein F, Schaal H, Timm J, Senff T. Müller L, et al. Among authors: klein f. Eur J Clin Microbiol Infect Dis. 2021 May;40(5):1063-1071. doi: 10.1007/s10096-021-04169-7. Epub 2021 Feb 3. Eur J Clin Microbiol Infect Dis. 2021. PMID: 33534090 Free PMC article.
198 results