35462165 25821194 20095134 19639279 27216633 24922583 24332624 25174927 28463561 23065321 27569066 23960840 20597030 24164628 25544146 22860156 33818841 19109019 18947224 - Search Results

Year	Number of Results
2008	2
2009	3
2010	1
2011	1
2012	2
2013	3
2014	5
2015	2
2016	2
2017	1
2021	1
2022	1

1

Discovery of small-molecule compounds and natural products against Parkinson's disease: Pathological mechanism and structural modification.

Zhong Z, He X, Ge J, Zhu J, Yao C, Cai H, Ye XY, Xie T, Bai R. Zhong Z, et al. Eur J Med Chem. 2022 Jul 5;237:114378. doi: 10.1016/j.ejmech.2022.114378. Epub 2022 Apr 18. Eur J Med Chem. 2022. PMID: 35462165 Review.

2

History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents.

Preti D, Baraldi PG, Moorman AR, Borea PA, Varani K. Preti D, et al. Med Res Rev. 2015 Jul;35(4):790-848. doi: 10.1002/med.21344. Epub 2015 Mar 27. Med Res Rev. 2015. PMID: 25821194 Review.

3

Adenosine A2A receptor antagonists as novel anti-Parkinsonian agents: a review of structure-activity relationships.

Azam F, Ibn-Rajab IA, Alruiad AA. Azam F, et al. Pharmazie. 2009 Dec;64(12):771-95. Pharmazie. 2009. PMID: 20095134 Review.

4

Recent developments in adenosine A2A receptor ligands.

Cristalli G, Müller CE, Volpini R. Cristalli G, et al. Handb Exp Pharmacol. 2009;(193):59-98. doi: 10.1007/978-3-540-89615-9_3. Handb Exp Pharmacol. 2009. PMID: 19639279 Review.

5

Discovery of potent adenosine A2a antagonists as potential anti-Parkinson disease agents. Non-linear QSAR analyses integrated with pharmacophore modeling.

Khanfar MA, Al-Qtaishat S, Habash M, Taha MO. Khanfar MA, et al. Chem Biol Interact. 2016 Jul 25;254:93-101. doi: 10.1016/j.cbi.2016.05.023. Epub 2016 May 20. Chem Biol Interact. 2016. PMID: 27216633

6

Optimization of 6-heterocyclic-2-(1H-pyrazol-1-yl)-N-(pyridin-2-yl)pyrimidin-4-amine as potent adenosine A2A receptor antagonists for the treatment of Parkinson's disease.

Zheng J, Yang Z, Li X, Li L, Ma H, Wang M, Zhang H, Zhen X, Zhang X. Zheng J, et al. ACS Chem Neurosci. 2014 Aug 20;5(8):674-82. doi: 10.1021/cn5000716. Epub 2014 Jun 23. ACS Chem Neurosci. 2014. PMID: 24922583 Free PMC article.

7

Replacement of amide with bioisosteres led to a new series of potent adenosine A2A receptor antagonists.

Yang Z, Li X, Ma H, Zheng J, Zhen X, Zhang X. Yang Z, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):152-5. doi: 10.1016/j.bmcl.2013.11.051. Epub 2013 Dec 1. Bioorg Med Chem Lett. 2014. PMID: 24332624

8

Towards next generation adenosine A(2A) receptor antagonists.

Yuan G, Jones GB. Yuan G, et al. Curr Med Chem. 2014;21(34):3918-35. doi: 10.2174/0929867321666140826115123. Curr Med Chem. 2014. PMID: 25174927 Review.

9

Discovery of Novel and Selective Adenosine A_2A Receptor Antagonists for Treating Parkinson's Disease through Comparative Structure-Based Virtual Screening.

Tian S, Wang X, Li L, Zhang X, Li Y, Zhu F, Hou T, Zhen X. Tian S, et al. J Chem Inf Model. 2017 Jun 26;57(6):1474-1487. doi: 10.1021/acs.jcim.7b00188. Epub 2017 May 15. J Chem Inf Model. 2017. PMID: 28463561

10

Ligand-, structure- and pharmacophore-based molecular fingerprints: a case study on adenosine A(1), A (2A), A (2B), and A (3) receptor antagonists.

Sirci F, Goracci L, Rodríguez D, van Muijlwijk-Koezen J, Gutiérrez-de-Terán H, Mannhold R. Sirci F, et al. J Comput Aided Mol Des. 2012 Nov;26(11):1247-66. doi: 10.1007/s10822-012-9612-8. Epub 2012 Oct 12. J Comput Aided Mol Des. 2012. PMID: 23065321

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