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Nanobodies and chemical cross-links advance the structural and functional analysis of PI3Kα.
Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2210769119. doi: 10.1073/pnas.2210769119. Epub 2022 Sep 12.
Proc Natl Acad Sci U S A. 2022.
PMID: 36095215
Free PMC article.
The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors.
Murphy RD, Chen T, Lin J, He R, Wu L, Pearson CR, Sharma S, Vander Kooi CD, Sinai AP, Zhang ZY, Vander Kooi CW, Gentry MS.
Murphy RD, et al.
J Biol Chem. 2022 Jul;298(7):102089. doi: 10.1016/j.jbc.2022.102089. Epub 2022 May 28.
J Biol Chem. 2022.
PMID: 35640720
Free PMC article.
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