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The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies.
Van der Perren A, Gelders G, Fenyi A, Bousset L, Brito F, Peelaerts W, Van den Haute C, Gentleman S, Melki R, Baekelandt V. Van der Perren A, et al. Acta Neuropathol. 2020 Jun;139(6):977-1000. doi: 10.1007/s00401-020-02157-3. Epub 2020 Apr 30. Acta Neuropathol. 2020. PMID: 32356200 Free PMC article.
α-Synuclein Seed Amplification in CSF and Brain from Patients with Different Brain Distributions of Pathological α-Synuclein in the Context of Co-Pathology and Non-LBD Diagnoses.
Arnold MR, Coughlin DG, Brumbach BH, Smirnov DS, Concha-Marambio L, Farris CM, Ma Y, Kim Y, Wilson EN, Kaye JA, Hiniker A, Woltjer RL, Galasko DR, Quinn JF. Arnold MR, et al. Ann Neurol. 2022 Oct;92(4):650-662. doi: 10.1002/ana.26453. Epub 2022 Jul 29. Ann Neurol. 2022. PMID: 35808984
Alpha-synuclein pathology, microgliosis, and parvalbumin neuron loss in the amygdala associated with enhanced fear in the Thy1-aSyn model of Parkinson's disease.
Torres ERS, Stanojlovic M, Zelikowsky M, Bonsberger J, Hean S, Mulligan C, Baldauf L, Fleming S, Masliah E, Chesselet MF, Fanselow MS, Richter F. Torres ERS, et al. Neurobiol Dis. 2021 Oct;158:105478. doi: 10.1016/j.nbd.2021.105478. Epub 2021 Aug 11. Neurobiol Dis. 2021. PMID: 34390837 Free PMC article.
32 results