36543887 33378537 34890791 34314817 36322143 37138765 35260846 36070751 34025358 34953315 35625816 36121477 36454749 35305541 36857431 35793625 - Search Results

Year	Number of Results
2021	5
2022	10
2023	4

1

Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation.

Mead RJ, Shan N, Reiser HJ, Marshall F, Shaw PJ. Mead RJ, et al. Nat Rev Drug Discov. 2023 Mar;22(3):185-212. doi: 10.1038/s41573-022-00612-2. Epub 2022 Dec 21. Nat Rev Drug Discov. 2023. PMID: 36543887 Free PMC article. Review.

2

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice.

Pattamatta A, Nguyen L, Olafson HR, Scotti MM, Laboissonniere LA, Richardson J, Berglund JA, Zu T, Wang ET, Ranum LPW. Pattamatta A, et al. Hum Mol Genet. 2021 Feb 25;29(24):3900-3918. doi: 10.1093/hmg/ddaa279. Hum Mol Genet. 2021. PMID: 33378537 Free PMC article.

3

Regulation of neuronal autophagy and the implications in neurodegenerative diseases.

Cai Q, Ganesan D. Cai Q, et al. Neurobiol Dis. 2022 Jan;162:105582. doi: 10.1016/j.nbd.2021.105582. Epub 2021 Dec 7. Neurobiol Dis. 2022. PMID: 34890791 Free PMC article. Review.

4

NRF2 as a therapeutic opportunity to impact in the molecular roadmap of ALS.

Jiménez-Villegas J, Ferraiuolo L, Mead RJ, Shaw PJ, Cuadrado A, Rojo AI. Jiménez-Villegas J, et al. Free Radic Biol Med. 2021 Sep;173:125-141. doi: 10.1016/j.freeradbiomed.2021.07.022. Epub 2021 Jul 24. Free Radic Biol Med. 2021. PMID: 34314817 Free article. Review.

5

Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors.

Ma L, Liang C, Wang J, Chang Q, Wang Y, Zhang W, Du Y, Sadan J, Chen JF. Ma L, et al. Hum Mol Genet. 2023 Apr 6;32(8):1252-1265. doi: 10.1093/hmg/ddac271. Hum Mol Genet. 2023. PMID: 36322143

6

C9ORF72 knockdown triggers FTD-like symptoms and cell pathology in mice.

Lopez-Herdoiza MB, Bauché S, Wilmet B, Le Duigou C, Roussel D, Frah M, Béal J, Devely G, Boluda S, Frick P, Bouteiller D, Dussaud S, Guillabert P, Dalle C, Dumont M, Camuzat A, Saracino D, Barbier M, Bruneteau G, Ravassard P, Neumann M, Nicole S, Le Ber I, Brice A, Latouche M. Lopez-Herdoiza MB, et al. Front Cell Neurosci. 2023 Apr 17;17:1155929. doi: 10.3389/fncel.2023.1155929. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37138765 Free PMC article.

7

Modelling amyotrophic lateral sclerosis in rodents.

Todd TW, Petrucelli L. Todd TW, et al. Nat Rev Neurosci. 2022 Apr;23(4):231-251. doi: 10.1038/s41583-022-00564-x. Epub 2022 Mar 8. Nat Rev Neurosci. 2022. PMID: 35260846 Review.

8

Choroid plexus-CSF-targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy.

Jang A, Petrova B, Cheong TC, Zawadzki ME, Jones JK, Culhane AJ, Shipley FB, Chiarle R, Wong ET, Kanarek N, Lehtinen MK. Jang A, et al. Neuron. 2022 Oct 19;110(20):3288-3301.e8. doi: 10.1016/j.neuron.2022.08.009. Epub 2022 Sep 6. Neuron. 2022. PMID: 36070751

9

C9ORF72: What It Is, What It Does, and Why It Matters.

Smeyers J, Banchi EG, Latouche M. Smeyers J, et al. Front Cell Neurosci. 2021 May 5;15:661447. doi: 10.3389/fncel.2021.661447. eCollection 2021. Front Cell Neurosci. 2021. PMID: 34025358 Free PMC article. Review.

10

RAN proteins in neurodegenerative disease: Repeating themes and unifying therapeutic strategies.

Guo S, Nguyen L, Ranum LPW. Guo S, et al. Curr Opin Neurobiol. 2022 Feb;72:160-170. doi: 10.1016/j.conb.2021.11.001. Epub 2021 Dec 22. Curr Opin Neurobiol. 2022. PMID: 34953315 Free PMC article. Review.

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