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Page 1
Inhibitory effects of anthracyclines on partially purified 5'-3' DNA helicase of Plasmodium falciparum.
Rattaprasert P, Suntornthiticharoen P, Limudomporn P, Thima K, Chavalitshewinkoon-Petmitr P. Rattaprasert P, et al. Malar J. 2022 Jul 11;21(1):216. doi: 10.1186/s12936-022-04238-y. Malar J. 2022. PMID: 35821133 Free PMC article.
DNA helicase activity of partially purified PfDH-B was examined by measuring its ability to unwind (32)P-labelled partial duplex DNA. ...CONCLUSION: Partial purification and characterization of 5'-3' DNA helicase of P. falci …
DNA helicase activity of partially purified PfDH-B was examined by measuring its ability to unwind (32)P-labelled parti …
An RNA Metabolism and Surveillance Quartet in the Major Histocompatibility Complex.
Zhou D, Lai M, Luo A, Yu CY. Zhou D, et al. Cells. 2019 Aug 30;8(9):1008. doi: 10.3390/cells8091008. Cells. 2019. PMID: 31480283 Free PMC article. Review.
DXO is a powerful enzyme with pyro-phosphohydrolase activity towards 5' triphosphorylated RNA, decapping and exoribonuclease activities of faulty nuclear RNA molecules. ...Here we briefly review the roles of (a) NELF-E on transcriptional pausing; (b) SKIV2L on turno …
DXO is a powerful enzyme with pyro-phosphohydrolase activity towards 5' triphosphorylated RNA, decapping and exoribonuclease activ …
Hepatitis C virus non-structural protein 3 interacts with cytosolic 5'(3')-deoxyribonucleotidase and partially inhibits its activity.
Fang CP, Li ZC, Yang CH, Cheng JC, Yeh YJ, Sun TH, Li HC, Juang YL, Lo SY. Fang CP, et al. PLoS One. 2013 Jul 9;8(7):e68736. doi: 10.1371/journal.pone.0068736. Print 2013. PLoS One. 2013. PMID: 23874742 Free PMC article.
In this study, a yeast two-hybrid screening experiment was conducted to identify cellular proteins interacting with HCV NS3 protein. Cytosolic 5'(3')-deoxyribonucleotidase (cdN, dNT-1) was found to interact with HCV NS3 protein. ...Deoxyribonucleotidases are present …
In this study, a yeast two-hybrid screening experiment was conducted to identify cellular proteins interacting with HCV NS3 protein. Cytosol …
Structural and enzymological characterization of a deoxyribonucleic acid dependent adenosine triphosphatase from KB cell nuclei.
Boxer LM, Korn D. Boxer LM, et al. Biochemistry. 1980 Jun 10;19(12):2623-33. doi: 10.1021/bi00553a014. Biochemistry. 1980. PMID: 6104981
We have purified to near homogeneity the single DNA-dependent ATPase activity that we have identified in extracts of KB cell nuclei. ...The purified enzyme has a specific activity of 5.9 X 10(5) nmol of ATP hydrolyzed per h per mg of protein and is devoid of …
We have purified to near homogeneity the single DNA-dependent ATPase activity that we have identified in extracts of KB cell n …
Dengue virus RNA polymerase NS5: a potential therapeutic target?
Rawlinson SM, Pryor MJ, Wright PJ, Jans DA. Rawlinson SM, et al. Curr Drug Targets. 2006 Dec;7(12):1623-38. doi: 10.2174/138945006779025383. Curr Drug Targets. 2006. PMID: 17168837 Review.
Dengue fever (DF)/dengue haemorrhagic fever (DHF) is the most common arthropod-borne viral infection, where it is now estimated that 2.5-3 billion people world-wide are at risk of infection. Currently there is no available treatment, in the form of vaccine or drug, …
Dengue fever (DF)/dengue haemorrhagic fever (DHF) is the most common arthropod-borne viral infection, where it is now estimated that 2.5 …
The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus.
Tanner JA, Zheng BJ, Zhou J, Watt RM, Jiang JQ, Wong KL, Lin YP, Lu LY, He ML, Kung HF, Kesel AJ, Huang JD. Tanner JA, et al. Chem Biol. 2005 Mar;12(3):303-11. doi: 10.1016/j.chembiol.2005.01.006. Chem Biol. 2005. PMID: 15797214 Free PMC article.
Six members of this class of compounds: bananin, iodobananin, vanillinbananin, ansabananin, eubananin, and adeninobananin were synthesized and tested as inhibitors of the SARS Coronavirus (SCV) helicase. Bananin, iodobananin, vanillinbananin, and eubananin were effective i …
Six members of this class of compounds: bananin, iodobananin, vanillinbananin, ansabananin, eubananin, and adeninobananin were synthesized a …
Association of polymorphisms in the cyclin D1 and XPD genes and susceptibility to cancers of the upper aero-digestive tract.
Buch S, Zhu B, Davis AG, Odom D, Siegfried JM, Grandis JR, Romkes M. Buch S, et al. Mol Carcinog. 2005 Apr;42(4):222-8. doi: 10.1002/mc.20086. Mol Carcinog. 2005. PMID: 15754315
XPD genetic polymorphisms resulting in amino acids substitutions may lead to alterations in TFIIH helicase activity, resulting in repair and transcription defects. Cyclin D1 is a key regulatory protein for the transition of cells from the G(1)-S cell cycle phase. .. …
XPD genetic polymorphisms resulting in amino acids substitutions may lead to alterations in TFIIH helicase activity, resulting …