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Endothelin-1 increases rat distal tubule acidification in vivo.
Wesson DE, Dolson GM. Wesson DE, et al. Am J Physiol. 1997 Oct;273(4):F586-94. doi: 10.1152/ajprenal.1997.273.4.F586. Am J Physiol. 1997. PMID: 9362336
By contrast, ET-1 increased distal tubule acidification in NaHCO3 animals predominantly by decreasing HCO3 secretion (-9.5 +/- 1.0 vs. -18.7 +/-1.8 pmol x mm(-1) x min(-1), P < 0.001) with less influence on H+ secretion. ...
By contrast, ET-1 increased distal tubule acidification in NaHCO3 animals predominantly by decreasing HCO3 secretion (-9.5 +/- 1.0 vs …
Reduced extracellular pH increases endothelin-1 secretion by human renal microvascular endothelial cells.
Wesson DE, Simoni J, Green DF. Wesson DE, et al. J Clin Invest. 1998 Feb 1;101(3):578-83. doi: 10.1172/JCI854. J Clin Invest. 1998. PMID: 9449690 Free PMC article.
Confluent cells were exposed to serum-free media for 24 h, then incubated in either control, acid, or alkaline serum-free media for 12 h. Standard growth media pH was 7.2 after equilibration with 5% CO2 at 37 degrees C and was made the pH of control media. Acid and alkalin …
Confluent cells were exposed to serum-free media for 24 h, then incubated in either control, acid, or alkaline serum-free media for 12 h. St …