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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 2
1978 2
1979 1
1980 7
1981 17
1982 14
1983 16
1984 29
1985 30
1986 37
1987 59
1988 98
1989 108
1990 134
1991 113
1992 153
1993 124
1994 162
1995 126
1996 142
1997 133
1998 116
1999 148
2000 126
2001 106
2002 108
2003 133
2004 112
2005 109
2006 105
2007 133
2008 102
2009 89
2010 105
2011 118
2012 124
2013 112
2014 99
2015 80
2016 81
2017 81
2018 78
2019 84
2020 71
2021 58
2022 47
2023 45
2024 21

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3,865 results

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Page 1
Labeling a protein with fluorophores using NHS ester derivitization.
Nanda JS, Lorsch JR. Nanda JS, et al. Methods Enzymol. 2014;536:87-94. doi: 10.1016/B978-0-12-420070-8.00008-8. Methods Enzymol. 2014. PMID: 24423269
For example, we use NHS ester chemistry to fluorescently label the amino terminus of a protein with the dye, 5-(and-6)-carboxyfluorescein, succinimidyl ester (5(6)-FAM, SE)....
For example, we use NHS ester chemistry to fluorescently label the amino terminus of a protein with the dye, 5-(and-6)-carboxyfluo
Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity.
Zhu J, Pedersen MD, Ahmed LS, Abdolalizadeh B, Grell AS, Berg JO, Thulstrup PW, Franzyk H, Edvinsson L, Sams A, Sheykhzade M, Hansen PR. Zhu J, et al. Int J Mol Sci. 2020 Feb 17;21(4):1343. doi: 10.3390/ijms21041343. Int J Mol Sci. 2020. PMID: 32079247 Free PMC article.
The objectives of the present work were: (i) synthesis of three single-labelled fluorescent analogues of h-alpha-CGRP by 9-fluorenylmethyloxycarbonyl (Fmoc)-based solid-phase peptide synthesis, and (ii) testing of their biological activity in isolated human, mouse, and rat arteri …
The objectives of the present work were: (i) synthesis of three single-labelled fluorescent analogues of h-alpha-CGRP by 9-fluorenylmethylox …
Identification and Quantitative Assessment of Uremic Solutes as Inhibitors of Renal Organic Anion Transporters, OAT1 and OAT3.
Hsueh CH, Yoshida K, Zhao P, Meyer TW, Zhang L, Huang SM, Giacomini KM. Hsueh CH, et al. Mol Pharm. 2016 Sep 6;13(9):3130-40. doi: 10.1021/acs.molpharmaceut.6b00332. Epub 2016 Aug 9. Mol Pharm. 2016. PMID: 27467266 Review.
We evaluated the effect of 72 uremic solutes on organic anion transporter 1 and 3 (OAT1 and OAT3) using a fluorescent probe substrate, 6-carboxyfluorescein. A total of 12 and 13 solutes were identified as inhibitors of OAT1 and OAT3, respectively. ...
We evaluated the effect of 72 uremic solutes on organic anion transporter 1 and 3 (OAT1 and OAT3) using a fluorescent probe substrate, 6
Fluorescence assessment of Lactococcus lactis viability.
Bunthof CJ, van den Braak S, Breeuwer P, Rombouts FM, Abee T. Bunthof CJ, et al. Int J Food Microbiol. 2000 Apr 10;55(1-3):291-4. doi: 10.1016/s0168-1605(00)00170-7. Int J Food Microbiol. 2000. PMID: 10791760 Review.
Fluorescent labeling of endocytic compartments.
Swanson J. Swanson J. Methods Cell Biol. 1989;29:137-51. doi: 10.1016/s0091-679x(08)60192-2. Methods Cell Biol. 1989. PMID: 2464119 Review. No abstract available.
Functional characterization of fluorescent hepcidin.
Dürrenberger F, Abbate V, Ma Y, Arno MC, Jaiash D, Parmar A, Marshall V, Latunde-Dada GO, Zimmermann T, Senn D, Altermatt P, Manolova V, Hider RC, Bansal SS. Dürrenberger F, et al. Bioconjug Chem. 2013 Sep 18;24(9):1527-32. doi: 10.1021/bc400121x. Epub 2013 Aug 14. Bioconjug Chem. 2013. PMID: 23888876
This functional property has been adopted in this study to assess the bioactivity and potency of a range of novel fluorescent hepcidin analogues. Hepcidin was selectively labeled with 6-carboxyfluorescein (CF) and 6-carboxytetramethylrhodamine (TMR) using Fmoc solid …
This functional property has been adopted in this study to assess the bioactivity and potency of a range of novel fluorescent hepcidin analo …
Biological fabrication of cellulose fibers with tailored properties.
Natalio F, Fuchs R, Cohen SR, Leitus G, Fritz-Popovski G, Paris O, Kappl M, Butt HJ. Natalio F, et al. Science. 2017 Sep 15;357(6356):1118-1122. doi: 10.1126/science.aan5830. Science. 2017. PMID: 28912238
In vitro model cultures of upland cotton (Gossypium hirsutum) are incubated with 6-carboxyfluorescein-glucose and dysprosium-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-glucose, where the glucose moiety acts as a carrier capable of traveling from the va …
In vitro model cultures of upland cotton (Gossypium hirsutum) are incubated with 6-carboxyfluorescein-glucose and dysprosium-1 …
Facile detection of melamine by a FAM-aptamer-G-quadruplex construct.
Su R, Zheng H, Dong S, Sun R, Qiao S, Sun H, Ma X, Zhang T, Sun C. Su R, et al. Anal Bioanal Chem. 2019 May;411(12):2521-2530. doi: 10.1007/s00216-019-01688-3. Epub 2019 Mar 13. Anal Bioanal Chem. 2019. PMID: 30863884
The development of a novel method for melamine detection that uses a FAM-aptamer-G-quadruplex construct due to the efficient quenching ability of an aptamer-linked G-quadruplex is reported herein. The construct, which is labeled with the fluorescent dye 6-carboxyfluores
The development of a novel method for melamine detection that uses a FAM-aptamer-G-quadruplex construct due to the efficient quenching abili …
Development of a fluorescence-based assay for screening of urate transporter 1 inhibitors using 6-carboxyfluorescein.
Zhou H, Zhong G, Bai J, Li X, Peng W, Zhang L, Li J. Zhou H, et al. Anal Biochem. 2021 Aug 1;626:114246. doi: 10.1016/j.ab.2021.114246. Epub 2021 May 7. Anal Biochem. 2021. PMID: 33965427
Herein, we report the development of a non-radioactive cell-based method for the screening of URAT1 inhibitors using the human embryonic kidney 293T cells stably expressing human URAT1, and 6-carboxyfluorescein (6-CFL) as a substrate. The URAT1-mediated transport of …
Herein, we report the development of a non-radioactive cell-based method for the screening of URAT1 inhibitors using the human embryonic kid …
N-terminal extended conjugates of the agonists and antagonists of both bradykinin receptor subtypes: structure-activity relationship, cell imaging using ligands conjugated with fluorophores and prospect for functionally active cargoes.
Gera L, Roy C, Bawolak MT, Charest-Morin X, Marceau F. Gera L, et al. Peptides. 2012 Apr;34(2):433-46. doi: 10.1016/j.peptides.2012.02.007. Epub 2012 Feb 18. Peptides. 2012. PMID: 22349904 Free article. Review.
Using this strategy, we produced and characterized the full set of fluorescent ligands by extending both agonists and antagonist peptides at both receptor subtypes with 5(6)-carboxyfluorescein (CF) and the epsilon-aminocaproyl (epsilon-ACA) optional spacer. ...
Using this strategy, we produced and characterized the full set of fluorescent ligands by extending both agonists and antagonist peptides at …
3,865 results