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1986 3
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Stereoselective metabolism of 9-methyl-, 9-hydroxymethyl- and 9,10-dimethylanthracenes: absolute configurations and optical purities of trans-dihydrodiol metabolites.
Von Tungeln LS, Fu PP. Von Tungeln LS, et al. Carcinogenesis. 1986 Jul;7(7):1135-41. doi: 10.1093/carcin/7.7.1135. Carcinogenesis. 1986. PMID: 3719909
Stereoselective metabolism of 9-methylanthracene (9-M-A), 9-hydroxymethylanthracene (9-OHM-A) and 9,10-dimethylanthracene (9,10-DM-A) by liver microsomes from untreated rats, and from rats pretreated with either 3-methylcholanthren …
Stereoselective metabolism of 9-methylanthracene (9-M-A), 9-hydroxymethylanthracene (9-OHM-A) and 9 …
9-Sulfooxymethylanthracene is an ultimate electrophilic and carcinogenic form of 9-hydroxymethylanthracene.
Flesher JW, Horn J, Lehner AF. Flesher JW, et al. Biochem Biophys Res Commun. 1998 Oct 9;251(1):239-43. doi: 10.1006/bbrc.1998.9448. Biochem Biophys Res Commun. 1998. PMID: 9790938
The common final step in a chain of enzymatic substitution reactions is the formation of an aralkylating agent bearing a good leaving group. Activation of hydroxymethyl derivatives, including 9-hydroxymethylanthracene, to electrophilic mutagens has been shown to be …
The common final step in a chain of enzymatic substitution reactions is the formation of an aralkylating agent bearing a good leaving group. …
Graphene Oxide as a Carbocatalyst for a Diels-Alder Reaction in an Aqueous Medium.
Girish YR, Pandit S, Pandit S, De M. Girish YR, et al. Chem Asian J. 2017 Sep 19;12(18):2393-2398. doi: 10.1002/asia.201701072. Epub 2017 Sep 4. Chem Asian J. 2017. PMID: 28815919
Herein, we report an efficient protocol for the DA reaction between 9-hydroxymethylanthracene and N-substituted maleimides using two-dimensional graphene oxide (GO) as a heterogeneous carbocatalyst in an aqueous medium at room temperature. ...
Herein, we report an efficient protocol for the DA reaction between 9-hydroxymethylanthracene and N-substituted maleimides usi …
The metabolism of 9-methylanthracene by rat-liver microsomal preparations.
Lamparczyk HS, McKay S, Farmer PB, Cary PD, Grover PL, Sims P. Lamparczyk HS, et al. Xenobiotica. 1986 Apr;16(4):325-33. doi: 10.3109/00498258609043535. Xenobiotica. 1986. PMID: 3716454
The metabolism of 9-methylanthracene by liver microsomal preparations from 3-methylcholanthrene-treated rats was examined. The principal metabolites identified were 9-hydroxymethylanthracene, the 1,2- and 3,4-dihydrodiols of the parent hydrocarbon and the 3,4 …
The metabolism of 9-methylanthracene by liver microsomal preparations from 3-methylcholanthrene-treated rats was examined. The princi …
Solvent effects on the 9-hydroxymethylanthracene + N-ethylmaleimide Diels-Alder reaction. A theoretical study.
García JI, Mayoral JA, Salvatella L. García JI, et al. J Org Chem. 2005 Feb 18;70(4):1456-8. doi: 10.1021/jo048257t. J Org Chem. 2005. PMID: 15704984
[structure: see text] The origin of the high reaction rates of the 9-hydroxymethylanthracene + N-ethylmaleimide Diels-Alder reaction in fluorous solvents and supercritical carbon dioxide is analyzed through a combination of regression analyses and theoretical calcul …
[structure: see text] The origin of the high reaction rates of the 9-hydroxymethylanthracene + N-ethylmaleimide Diels-Alder re …
Activation of promutagens by endogenous and heterologous sulfotransferases expressed in continuous cell cultures.
Glatt H, Pauly K, Piée-Staffa A, Seidel A, Hornhardt S, Czich A. Glatt H, et al. Toxicol Lett. 1994 Jun;72(1-3):13-21. doi: 10.1016/0378-4274(94)90005-1. Toxicol Lett. 1994. PMID: 8202924
We therefore analysed the abilities of cytosols from mammalian cell lines to activate benzylic alcohols (1-hydroxymethylpyrene and 9-hydroxymethylanthracene) to mutagens detectable in Salmonella typhimurium TA98. ...Cytosol of these cells effectively activated 1-hyd …
We therefore analysed the abilities of cytosols from mammalian cell lines to activate benzylic alcohols (1-hydroxymethylpyrene and 9- …
Stable heterologous expression of hydroxysteroid sulphotransferase in Chinese hamster V79 cells and their use for toxicological investigations.
Czich A, Bartsch I, Dogra S, Hornhardt S, Glatt HR. Czich A, et al. Chem Biol Interact. 1994 Jun;92(1-3):119-28. doi: 10.1016/0009-2797(94)90058-2. Chem Biol Interact. 1994. PMID: 8033247
The mRNA, protein and enzyme activity levels in the constructed cell lines (V79rSTa-1 and V79rSTa-2) were measured, and the cells were also used in mutagenicity and cytotoxicity investigations with benzylic alcohols. 1-Hydroxymethylpyrene, 9-hydroxymethylanthracene …
The mRNA, protein and enzyme activity levels in the constructed cell lines (V79rSTa-1 and V79rSTa-2) were measured, and the cells were also …
Solvophobic acceleration of Diels-Alder reactions in supercritical carbon dioxide.
Qian J, Timko MT, Allen AJ, Russell CJ, Winnik B, Buckley B, Steinfeld JI, Tester JW. Qian J, et al. J Am Chem Soc. 2004 May 5;126(17):5465-74. doi: 10.1021/ja030620a. J Am Chem Soc. 2004. PMID: 15113218
The rate of the Diels-Alder reaction between N-ethylmaleimide and 9-hydroxymethylanthracene in supercritical carbon dioxide (scCO(2)) was determined by following the disappearance of 9-hydroxymethylanthracene with in situ UV/vis absorption spectroscopy …
The rate of the Diels-Alder reaction between N-ethylmaleimide and 9-hydroxymethylanthracene in supercritical carbon dioxide (s …
Activation of benzylic alcohols to mutagens by human hepatic sulphotransferases.
Glatt H, Seidel A, Harvey RG, Coughtrie MW. Glatt H, et al. Mutagenesis. 1994 Nov;9(6):553-7. doi: 10.1093/mutage/9.6.553. Mutagenesis. 1994. PMID: 7854148
Male and female rat liver cytosol showed higher sulphotransferase activities towards 1-hydroxymethylpyrene, 9-hydroxymethylanthracene, 7-hydroxymethyl-12-methylbenz[a]anthracene and 4H-cyclopenta[def]chrysen-4-ol than human liver cytosol. ...
Male and female rat liver cytosol showed higher sulphotransferase activities towards 1-hydroxymethylpyrene, 9-hydroxymethylanthrac …
Stereoselective fungal metabolism of methylated anthracenes.
Cerniglia CE, Campbell WL, Fu PP, Freeman JP, Evans FE. Cerniglia CE, et al. Appl Environ Microbiol. 1990 Mar;56(3):661-8. doi: 10.1128/aem.56.3.661-668.1990. Appl Environ Microbiol. 1990. PMID: 2317041 Free PMC article.
The metabolism of 9-methylanthracene (9-MA), 9-hydroxymethylanthracene (9-OHMA), and 9,10-dimethylanthracene (9,10-DMA) by the fungus Cunninghamella elegans ATCC 36112 is described. ...For 9-MA metabolism, the major metaboli …
The metabolism of 9-methylanthracene (9-MA), 9-hydroxymethylanthracene (9-OHMA), and 9,10-dimethyl …
16 results