Characterization of large linear plasmids in mycobacteria

J Bacteriol. 1997 Apr;179(8):2753-6. doi: 10.1128/jb.179.8.2753-2756.1997.

Abstract

Linear plasmids were found in Mycobacterium xenopi, M. branderi, and M. celatum. These elements represented a wide size range (from 20 to 320 kb), had Streptomyces-like terminal structures, and defined five hybridization groups. Cross-hybridization and common restriction fragment length polymorphism patterns of plasmids from the different species suggest either genetic exchange or a common ancestry of the species.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blotting, Southern
  • DNA Topoisomerases, Type I
  • Electrophoresis, Gel, Pulsed-Field / methods
  • Exodeoxyribonucleases
  • Molecular Weight
  • Mycobacterium / chemistry*
  • Nucleic Acid Conformation
  • Plasmids / analysis*
  • Plasmids / chemistry
  • Plasmids / genetics
  • Polymorphism, Restriction Fragment Length

Substances

  • Exodeoxyribonucleases
  • exodeoxyribonuclease III
  • DNA Topoisomerases, Type I