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Global metabolomic analysis of human saliva and plasma from healthy and diabetic subjects, with and without periodontal disease.
Barnes VM, Kennedy AD, Panagakos F, Devizio W, Trivedi HM, Jönsson T, Guo L, Cervi S, Scannapieco FA. Barnes VM, et al. PLoS One. 2014 Aug 18;9(8):e105181. doi: 10.1371/journal.pone.0105181. eCollection 2014. PLoS One. 2014. PMID: 25133529 Free PMC article.
Metabolite profiling was performed using Metabolon's platform technology. A total of 772 metabolites were found in plasma and 475 in saliva. ...Global untargeted metabolic profiling of human saliva in diabetics replicated the metab …
Metabolite profiling was performed using Metabolon's platform technology. A total of 772 metabolites were found in plasma and …
Salivaomics.
Wong DT. Wong DT. J Am Dent Assoc. 2012 Oct;143(10 Suppl):19S-24S. doi: 10.14219/jada.archive.2012.0339. J Am Dent Assoc. 2012. PMID: 23034834 Review.
The first is the need to develop and optimize diagnostic tools tailored to saliva. The second is the need to substantiate the scientific underpinnings of salivary biomarkers reflecting systemic diseases. ...The translation of the scientific mechanisms of systemic diseases …
The first is the need to develop and optimize diagnostic tools tailored to saliva. The second is the need to substantiate the scienti …
Recent and potential developments of biofluid analyses in metabolomics.
Zhang A, Sun H, Wang P, Han Y, Wang X. Zhang A, et al. J Proteomics. 2012 Feb 2;75(4):1079-88. doi: 10.1016/j.jprot.2011.10.027. Epub 2011 Nov 4. J Proteomics. 2012. PMID: 22079244 Review.
Metabolomics, one of the 'omic' sciences in systems biology, is the global assessment and validation of endogenous small-molecule metabolites within a biologic system. ...A majority of these metabolites are being applied to metabolic profiling of the biologic …
Metabolomics, one of the 'omic' sciences in systems biology, is the global assessment and validation of endogenous small-molec …
Metabolomic Profiling of Biological Reference Materials using a Multiplatform High-Resolution Mass Spectrometric Approach.
Aristizabal-Henao JJ, Lemas DJ, Griffin EK, Costa KA, Camacho C, Bowden JA. Aristizabal-Henao JJ, et al. J Am Soc Mass Spectrom. 2021 Sep 1;32(9):2481-2489. doi: 10.1021/jasms.1c00194. Epub 2021 Aug 13. J Am Soc Mass Spectrom. 2021. PMID: 34388338
The establishment of baseline metabolomics data for human reference materials using complementary/orthogonal data acquisition strategies can help to alleviate some of these challenges. ...Significant differences were observed in the metabolomic fingerprints b …
The establishment of baseline metabolomics data for human reference materials using complementary/orthogonal data acquisition …
Metabolomics Analyses of Saliva Detect Novel Biomarkers of Alzheimer's Disease.
Huan T, Tran T, Zheng J, Sapkota S, MacDonald SW, Camicioli R, Dixon RA, Li L. Huan T, et al. J Alzheimers Dis. 2018;65(4):1401-1416. doi: 10.3233/JAD-180711. J Alzheimers Dis. 2018. PMID: 30175979
Using a non-invasive biofluid (saliva), we apply a powerful metabolomics workflow for unbiased biomarker discovery in Alzheimer's disease (AD). ...Given its wide availability and convenient accessibility, saliva is a biofluid that can promote diversifi …
Using a non-invasive biofluid (saliva), we apply a powerful metabolomics workflow for unbiased biomarker discovery in Alzheime …
Metabolome analysis for discovering biomarkers of gastroenterological cancer.
Suzuki M, Nishiumi S, Matsubara A, Azuma T, Yoshida M. Suzuki M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 1;966:59-69. doi: 10.1016/j.jchromb.2014.02.042. Epub 2014 Mar 1. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 24636738 Review.
Thus, metabolome analysis allows one to survey the global changes in an organism's metabolic profile and gain a holistic understanding of the changes that occur in organisms during various biological processes, e.g., during disease development. In clin …
Thus, metabolome analysis allows one to survey the global changes in an organism's metabolic profile and gain a …
Validated Ultra-High-Performance Liquid Chromatography Hybrid High-Resolution Mass Spectrometry and Laser-Assisted Rapid Evaporative Ionization Mass Spectrometry for Salivary Metabolomics.
Wijnant K, Van Meulebroek L, Pomian B, De Windt K, De Henauw S, Michels N, Vanhaecke L. Wijnant K, et al. Anal Chem. 2020 Apr 7;92(7):5116-5124. doi: 10.1021/acs.analchem.9b05598. Epub 2020 Mar 18. Anal Chem. 2020. PMID: 32150679
Whereas urine and blood are typically targeted in clinical research, saliva represents an interesting alternative because its intrinsic metabolome is chemically diverse and reflective for various biological processes. ...For the majority of the profiled metab …
Whereas urine and blood are typically targeted in clinical research, saliva represents an interesting alternative because its intrins …
New insights into cardiovascular and lipid metabolomics.
Giovane A, Balestrieri A, Napoli C. Giovane A, et al. J Cell Biochem. 2008 Oct 15;105(3):648-54. doi: 10.1002/jcb.21875. J Cell Biochem. 2008. PMID: 18729082 Review.
Metabolomics is the study of metabolite profiles in biological samples, particularly urine, saliva, blood plasma and fat biopsies. ...A wealth of information about metabolites has been accumulated with global profiling tools and several candidat …
Metabolomics is the study of metabolite profiles in biological samples, particularly urine, saliva, blood plasma and fa …
Saliva and urine metabolic profiling reveals altered amino acid and energy metabolism in male farmers exposed to pesticides in Madhya Pradesh State, India.
Ch R, Singh AK, Pathak MK, Singh A, Kesavachandran CN, Bihari V, Mudiam MKR. Ch R, et al. Chemosphere. 2019 Jul;226:636-644. doi: 10.1016/j.chemosphere.2019.03.157. Epub 2019 Mar 27. Chemosphere. 2019. PMID: 30954898
Globally, the human population is exposed to low doses of pesticides due to its extensive use in agriculture. ...Saliva and urine samples were collected from 51 pesticides applicators and acquired metabolic profiles of urine and saliva samples u …
Globally, the human population is exposed to low doses of pesticides due to its extensive use in agriculture. ...Saliva …
Protocol for quality control in metabolic profiling of biological fluids by U(H)PLC-MS.
Gika HG, Zisi C, Theodoridis G, Wilson ID. Gika HG, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jan 1;1008:15-25. doi: 10.1016/j.jchromb.2015.10.045. Epub 2015 Nov 10. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 26610079
The process of untargeted metabolic profiling/phenotyping of complex biological matrices, i.e., biological fluids such as blood plasma/serum, saliva, bile, and tissue extracts, provides the analyst with a wide range of challenges. ...Whilst the use of these procedur …
The process of untargeted metabolic profiling/phenotyping of complex biological matrices, i.e., biological fluids such as blood plasm …
18 results