Vegetable, fruit and antioxidant nutrient consumption and subsequent risk of hepatocellular carcinoma: a prospective cohort study in Japan

Br J Cancer. 2009 Jan 13;100(1):181-4. doi: 10.1038/sj.bjc.6604843.

Abstract

In a population-based prospective study of 19,998 Japanese individuals, consumption of vegetables, green-yellow and green leafy vegetables was inversely associated with the risk of hepatocellular carcinoma (101 cases), with multivariable hazard ratios for the highest vs lowest tertile of 0.61 (95% confidence interval (CI)=0.36-1.03, P(trend)=0.07), 0.65 (95% CI=0.39-1.08, P(trend)=0.06) and 0.59 (95% CI=0.35-1.01, P(trend)=0.04), respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Antioxidants / administration & dosage*
  • Ascorbic Acid / administration & dosage
  • Carcinoma, Hepatocellular / prevention & control*
  • Cohort Studies
  • Female
  • Fruit*
  • Humans
  • Liver Neoplasms / prevention & control*
  • Male
  • Middle Aged
  • Prospective Studies
  • Risk
  • Vegetables*

Substances

  • Antioxidants
  • Ascorbic Acid