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A Phenotypic High-Content Screening Assay to Identify Regulators of Membrane Protein Localization.
Smith LK, Thomas DW, Simpson KJ, Humbert PO. Smith LK, et al. Assay Drug Dev Technol. 2016 Oct;14(8):478-488. doi: 10.1089/adt.2016.733. Epub 2016 Sep 23. Assay Drug Dev Technol. 2016. PMID: 27661290
Despite this, little is known about how Scribble membrane localization is regulated. Here, we describe the development and application of a phenotypic high-content screening assay that is designed to specifically quantify …
Despite this, little is known about how Scribble membrane localization is regulated. Here, we describe the development …
Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry.
Riva L, Song OR, Prentoe J, Helle F, L'homme L, Gattolliat CH, Vandeputte A, Fénéant L, Belouzard S, Baumert TF, Asselah T, Bukh J, Brodin P, Cocquerel L, Rouillé Y, Dubuisson J. Riva L, et al. J Virol. 2018 Apr 27;92(10):e01982-17. doi: 10.1128/JVI.01982-17. Print 2018 May 15. J Virol. 2018. PMID: 29491159 Free PMC article.
Through a high-content virus infection screening analysis with a library of 1,120 biologically active chemical compounds, we identified SB258585, an antagonist of serotonin receptor 6 (5-HT6), as a new inhibitor of HCV entry in liver-derived cel …
Through a high-content virus infection screening analysis with a library of 1,120 biologically active chemical c …
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