Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 1
1998 1
1999 2
2000 1
2004 5
2005 2
2006 2
2007 2
2008 4
2009 5
2010 6
2011 10
2012 12
2013 16
2014 11
2015 17
2016 21
2017 16
2018 20
2019 19
2020 23
2021 28
2022 34
2023 31
2024 19

Text availability

Article attribute

Article type

Publication date

Search Results

266 results

Results by year

Citations

6 articles found by citation matching

Search results

Filters applied: . Clear all
Page 1
Polygenic risk score for genetic evaluation of prostate cancer risk in Asian populations: A narrative review.
Song SH, Byun SS. Song SH, et al. Investig Clin Urol. 2021 May;62(3):256-266. doi: 10.4111/icu.20210124. Investig Clin Urol. 2021. PMID: 33943048 Free PMC article. Review.
Decreasing costs of genetic testing and interest in disease inheritance has changed the landscape of cancer prediction in prostate cancer (PCa), and guidelines now include genetic testing for high-risk groups. ...Multifaceted disor …
Decreasing costs of genetic testing and interest in disease inheritance has changed the landscape of cancer prediction
Prostate cancer risk prediction using a polygenic risk score.
Sipeky C, Talala KM, Tammela TLJ, Taari K, Auvinen A, Schleutker J. Sipeky C, et al. Sci Rep. 2020 Oct 13;10(1):17075. doi: 10.1038/s41598-020-74172-z. Sci Rep. 2020. PMID: 33051487 Free PMC article.
Individual genetic risk through establishment of a polygenic risk score based on 55 PC risk SNPs identified through the Finnish subset of the Collaborative Oncological Gene-Environment Study was assessed. ...The polygenic risk
Individual genetic risk through establishment of a polygenic risk score based on 55 PC risk SNPs i …
A Polygenic Risk Score for Prostate Cancer Risk Prediction.
Schaffer KR, Shi M, Shelley JP, Tosoian JJ, Kachuri L, Witte JS, Mosley JD. Schaffer KR, et al. JAMA Intern Med. 2023 Apr 1;183(4):386-388. doi: 10.1001/jamainternmed.2022.6795. JAMA Intern Med. 2023. PMID: 36877498 Free PMC article.
This retrospective cohort study compares 2 risk calculator systems that compute the probabilities of finding high-grade or any cancer on biopsy results in men undergoing a first prostate biopsy....
This retrospective cohort study compares 2 risk calculator systems that compute the probabilities of finding high-grade or any can
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA, Benlloch S, Dadaev T, Brook MN, Sahimi A, Hoffmann TJ, Takahashi A, Matsuda K, Momozawa Y, Fujita M, Muir K, Lophatananon A, Wan P, Le Marchand L, Wilkens LR, Stevens VL, Gapstur SM, Carter BD, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Giles GG, Southey MC, MacInnis RJ, Cybulski C, Wokołorczyk D, Lubiński J, Neal DE, Donovan JL, Hamdy FC, Martin RM, Nordestgaard BG, Nielsen SF, Weischer M, Bojesen SE, Røder MA, Iversen P, Batra J, Chambers S, Moya L, Horvath L, Clements JA, Tilley W, Risbridger GP, Gronberg H, Aly M, Szulkin R, Eklund M, Nordström T, Pashayan N, Dunning AM, Ghoussaini M, Travis RC, Key TJ, Riboli E, Park JY, Sellers TA, Lin HY, Albanes D, Weinstein SJ, Mucci LA, Giovannucci E, Lindstrom S, Kraft P, Hunter DJ, Penney KL, Turman C, Tangen CM, Goodman PJ, Thompson IM Jr, Hamilton RJ, Fleshner NE, Finelli A, Parent MÉ, Stanford JL, Ostrander EA, Geybels MS, Koutros S, Freeman LEB, Stampfer M, Wolk A, Håkansson N, Andriole GL, Hoover RN, Machiela MJ, Sørensen KD, Borre M, Blot WJ, Zheng W, Yeboah ED, Mensah JE, Lu YJ, Zhang HW, Feng N, Mao X, Wu Y, Zhao SC, Sun Z, Thibodeau SN, M… See abstract for full author list ➔ Conti DV, et al. Nat Genet. 2021 Jan;53(1):65-75. doi: 10.1038/s41588-020-00748-0. Epub 2021 Jan 4. Nat Genet. 2021. PMID: 33398198 Free PMC article.
We conducted a multiancestry meta-analysis of prostate cancer genome-wide association studies (107,247 cases and 127,006 controls) and identified 86 new genetic risk variants independently associated with prostate cancer risk, brin …
We conducted a multiancestry meta-analysis of prostate cancer genome-wide association studies (107,247 cases and 127,006 contr …
Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.
Chen F, Madduri RK, Rodriguez AA, Darst BF, Chou A, Sheng X, Wang A, Shen J, Saunders EJ, Rhie SK, Bensen JT, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Sanderson M, John EM, Park JY, Xu J, Wang Y, Berndt SI, Huff CD, Yeboah ED, Tettey Y, Lachance J, Tang W, Rentsch CT, Cho K, Mcmahon BH, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Sellers TA, Yamoah K, Murphy AB, Crawford DC, Patel AV, Bush WS, Aldrich MC, Cussenot O, Petrovics G, Cullen J, Neslund-Dudas CM, Stern MC, Kote-Jarai Z, Govindasami K, Cook MB, Chokkalingam AP, Hsing AW, Goodman PJ, Hoffmann TJ, Drake BF, Hu JJ, Keaton JM, Hellwege JN, Clark PE, Jalloh M, Gueye SM, Niang L, Ogunbiyi O, Idowu MO, Popoola O, Adebiyi AO, Aisuodionoe-Shadrach OI, Ajibola HO, Jamda MA, Oluwole OP, Nwegbu M, Adusei B, Mante S, Darkwa-Abrahams A, Mensah JE, Diop H, Van Den Eeden SK, Blanchet P, Fowke JH, Casey G, Hennis AJ, Lubwama A, Thompson IM Jr, Leach R, Easton DF, Preuss MH, Loos RJ, Gundell SM, Wan P, Mohler JL, Fontham ET, Smith GJ, Taylor JA, Srivastava S, Eeles RA, Carpten JD, Kibel AS, Multigner L, Parent MÉ, Menegaux F, Cancel-Tassin G, Klein EA, Andrews C, Rebbeck TR, Brureau L… See abstract for full author list ➔ Chen F, et al. Eur Urol. 2023 Jul;84(1):13-21. doi: 10.1016/j.eururo.2023.01.022. Epub 2023 Mar 3. Eur Urol. 2023. PMID: 36872133
BACKGROUND: Genetic factors play an important role in prostate cancer (PCa) susceptibility. ...PATIENT SUMMARY: In this large genetic study in men of African ancestry, we discovered nine novel prostate cancer (PCa) risk variants. . …
BACKGROUND: Genetic factors play an important role in prostate cancer (PCa) susceptibility. ...PATIENT SUMMARY: In this …
Polygenic risk score in prostate cancer.
Oh JJ, Hong SK. Oh JJ, et al. Curr Opin Urol. 2022 Sep 1;32(5):466-471. doi: 10.1097/MOU.0000000000001029. Epub 2022 Jul 18. Curr Opin Urol. 2022. PMID: 35855560 Review.
PURPOSE OF REVIEW: This study was conducted in order to review the outcomes regarding polygenic risk score (PRS) in prediction of prostate cancer (PCa). ...Genetic risk prediction models for PCa that include hundreds …
PURPOSE OF REVIEW: This study was conducted in order to review the outcomes regarding polygenic risk score (PRS) in …
Towards clinical utility of polygenic risk scores.
Lambert SA, Abraham G, Inouye M. Lambert SA, et al. Hum Mol Genet. 2019 Nov 21;28(R2):R133-R142. doi: 10.1093/hmg/ddz187. Hum Mol Genet. 2019. PMID: 31363735 Review.
Polygenic risk scores (PRS) aggregate the effects of many genetic variants across the human genome into a single score and have recently been shown to have predictive value for multiple common diseases. ...PRS analysis for these diseases frequen
Polygenic risk scores (PRS) aggregate the effects of many genetic variants across the human genome into a single sco
A Polygenic Risk Score Predicts Incident Prostate Cancer Risk in Older Men but Does Not Select for Clinically Significant Disease.
Bakshi A, Riaz M, Orchard SG, Carr PR, Joshi AD, Cao Y, Rebello R, Nguyen-Dumont T, Southey MC, Millar JL, Gately L, Gibbs P, Ford LG, Parnes HL, Chan AT, McNeil JJ, Lacaze P. Bakshi A, et al. Cancers (Basel). 2021 Nov 19;13(22):5815. doi: 10.3390/cancers13225815. Cancers (Basel). 2021. PMID: 34830967 Free PMC article.
Despite the high prevalence of prostate cancer in older men, the predictive value of a polygenic risk score (PRS) remains uncertain in men aged 70 years. ...After excluding participants with a history of prostate cancer at e …
Despite the high prevalence of prostate cancer in older men, the predictive value of a polygenic risk
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Schumacher FR, Al Olama AA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D, Anokian E, Cieza-Borrella C, Goh C, Brook MN, Sheng X, Fachal L, Dennis J, Tyrer J, Muir K, Lophatananon A, Stevens VL, Gapstur SM, Carter BD, Tangen CM, Goodman PJ, Thompson IM Jr, Batra J, Chambers S, Moya L, Clements J, Horvath L, Tilley W, Risbridger GP, Gronberg H, Aly M, Nordström T, Pharoah P, Pashayan N, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Albanes D, Weinstein S, Wolk A, Håkansson N, West CML, Dunning AM, Burnet N, Mucci LA, Giovannucci E, Andriole GL, Cussenot O, Cancel-Tassin G, Koutros S, Beane Freeman LE, Sorensen KD, Orntoft TF, Borre M, Maehle L, Grindedal EM, Neal DE, Donovan JL, Hamdy FC, Martin RM, Travis RC, Key TJ, Hamilton RJ, Fleshner NE, Finelli A, Ingles SA, Stern MC, Rosenstein BS, Kerns SL, Ostrer H, Lu YJ, Zhang HW, Feng N, Mao X, Guo X, Wang G, Sun Z, Giles GG, Southey MC, MacInnis RJ, FitzGerald LM, Kibel AS, Drake BF, Vega A, Gómez-Caamaño A, Szulkin R, Eklund M, Kogevinas M, Llorca J, Castaño-Vinyals G, Penney KL, Stampfer M, Park JY, Sellers TA, Lin HY, Stanford JL, Cybulski C, Wokolorczyk D, Lubinski J, Ostrander EA, Geybels MS, Nordestga… See abstract for full author list ➔ Schumacher FR, et al. Nat Genet. 2018 Jul;50(7):928-936. doi: 10.1038/s41588-018-0142-8. Epub 2018 Jun 11. Nat Genet. 2018. PMID: 29892016 Free PMC article.
The combination of all loci captured 28.4% of the PrCa familial relative risk, and a polygenic risk score conferred an elevated PrCa risk for men in the ninetieth to ninety-ninth percentiles (relative risk = 2.69; 95% confidence interval …
The combination of all loci captured 28.4% of the PrCa familial relative risk, and a polygenic risk score confer …
Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer.
Karunamuni RA, Huynh-Le MP, Fan CC, Thompson W, Eeles RA, Kote-Jarai Z, Muir K, Lophatananon A; UKGPCS collaborators; Schleutker J, Pashayan N, Batra J; APCB BioResource (Australian Prostate Cancer BioResource); Grönberg H, Walsh EI, Turner EL, Lane A, Martin RM, Neal DE, Donovan JL, Hamdy FC, Nordestgaard BG, Tangen CM, MacInnis RJ, Wolk A, Albanes D, Haiman CA, Travis RC, Stanford JL, Mucci LA, West CML, Nielsen SF, Kibel AS, Wiklund F, Cussenot O, Berndt SI, Koutros S, Sørensen KD, Cybulski C, Grindedal EM, Park JY, Ingles SA, Maier C, Hamilton RJ, Rosenstein BS, Vega A; IMPACT Study Steering Committee and Collaborators; Kogevinas M, Penney KL, Teixeira MR, Brenner H, John EM, Kaneva R, Logothetis CJ, Neuhausen SL, Razack A, Newcomb LF; Canary PASS Investigators; Gamulin M, Usmani N, Claessens F, Gago-Dominguez M, Townsend PA, Roobol MJ, Zheng W; Profile Study Steering Committee; Mills IG, Andreassen OA, Dale AM, Seibert TM; PRACTICAL Consortium. Karunamuni RA, et al. Prostate Cancer Prostatic Dis. 2021 Jun;24(2):532-541. doi: 10.1038/s41391-020-00311-2. Epub 2021 Jan 8. Prostate Cancer Prostatic Dis. 2021. PMID: 33420416 Free PMC article.
BACKGROUND: Polygenic hazard scores (PHS) can identify individuals with increased risk of prostate cancer. ...By contrast, no significant differences were observed in PPV of PSA testing for clinically significant prostate cancer. CONCLUSI …
BACKGROUND: Polygenic hazard scores (PHS) can identify individuals with increased risk of prostate cancer. ...By …
266 results