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416,699 results

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The following term was not found in PubMed: SURVEY-CLASSIFIER
Page 1
The landscape and therapeutic relevance of cancer-associated transcript fusions.
Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG. Yoshihara K, et al. Oncogene. 2015 Sep 10;34(37):4845-54. doi: 10.1038/onc.2014.406. Epub 2014 Dec 15. Oncogene. 2015. PMID: 25500544 Free PMC article.
Our fusion prediction was validated by evidence of a genomic rearrangement for 78 of 79 fusions in 48 glioma samples where whole-genome sequencing data were available. ...In summary, we described the landscape of transcript fusions detected across a large num …
Our fusion prediction was validated by evidence of a genomic rearrangement for 78 of 79 fusions in 48 glioma samples where who …
TumorFusions: an integrative resource for cancer-associated transcript fusions.
Hu X, Wang Q, Tang M, Barthel F, Amin S, Yoshihara K, Lang FM, Martinez-Ledesma E, Lee SH, Zheng S, Verhaak RGW. Hu X, et al. Nucleic Acids Res. 2018 Jan 4;46(D1):D1144-D1149. doi: 10.1093/nar/gkx1018. Nucleic Acids Res. 2018. PMID: 29099951 Free PMC article.
Gene fusion represents a class of molecular aberrations in cancer and has been exploited for therapeutic purposes. ...The portal spans 33 cancer types in TCGA. Fusion transcripts were identified via a uniform pipeline, including filtering against a list of 3838 tran …
Gene fusion represents a class of molecular aberrations in cancer and has been exploited for therapeutic purposes. ...The portal span …
How cells fuse.
Brukman NG, Uygur B, Podbilewicz B, Chernomordik LV. Brukman NG, et al. J Cell Biol. 2019 May 6;218(5):1436-1451. doi: 10.1083/jcb.201901017. Epub 2019 Apr 1. J Cell Biol. 2019. PMID: 30936162 Free PMC article. Review.
Some fusions are controlled by a single fusogen; other fusions depend on several proteins that either work together throughout the fusion pathway or drive distinct stages. Furthermore, some fusions require fusogens to be present on both fusing membrane …
Some fusions are controlled by a single fusogen; other fusions depend on several proteins that either work together throughout …
Fusion-positive skin/adnexal carcinomas.
Agaimy A. Agaimy A. Genes Chromosomes Cancer. 2022 May;61(5):274-284. doi: 10.1002/gcc.23031. Epub 2022 Mar 7. Genes Chromosomes Cancer. 2022. PMID: 35167714 Review.
In the last two decades, several skin adnexal entities driven by specific fusions have been described; some of them represent new entities (eg, secretory carcinoma harboring NTRK fusions), while others are old established entities with newly discovered underlying ge …
In the last two decades, several skin adnexal entities driven by specific fusions have been described; some of them represent new ent …
The Fate of Fusions.
Clawson G. Clawson G. Cells. 2018 Dec 29;8(1):13. doi: 10.3390/cells8010013. Cells. 2018. PMID: 30597927 Free PMC article. Review.
The concept of leukocyte-tumor cell fusion as a significant driver of cancer progression has been around a long time, and has garnered growing support over the last several years. ...While there are a number of attractive features with this story on the surface, the variou …
The concept of leukocyte-tumor cell fusion as a significant driver of cancer progression has been around a long time, and has garnere …
Radioscapholunate fusions.
McGuire DT, Bain GI. McGuire DT, et al. J Wrist Surg. 2012 Nov;1(2):135-40. doi: 10.1055/s-0032-1330071. J Wrist Surg. 2012. PMID: 24179717 Free PMC article.
Radiocarpal fusions are performed for a variety of indications, most commonly for debilitating painful arthritis. ...Techniques for partial carpal fusions have improved and now include distal scaphoid and triquetrum excision, which improves range of motion and fu …
Radiocarpal fusions are performed for a variety of indications, most commonly for debilitating painful arthritis. ...Techniques for p …
NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis.
Nagasaka M, Ou SI. Nagasaka M, et al. Trends Cancer. 2022 Mar;8(3):242-258. doi: 10.1016/j.trecan.2021.11.003. Epub 2022 Jan 5. Trends Cancer. 2022. PMID: 34996744 Free article. Review.
Neuregulin-1 (NRG1) is the main physiological ligand to HER3. NRG1 fusion (NRG1+) was first reported in a breast cancer cell line and NRG2 fusions have recently been identified in solid tumors. It is postulated that NRG1 fusions, through mostly transmembrane …
Neuregulin-1 (NRG1) is the main physiological ligand to HER3. NRG1 fusion (NRG1+) was first reported in a breast cancer cell line and …
Gene fusions in gastrointestinal tract cancers.
Rahi H, Olave MC, Fritchie KJ, Greipp PT, Halling KC, Kipp BR, Graham RP. Rahi H, et al. Genes Chromosomes Cancer. 2022 May;61(5):285-297. doi: 10.1002/gcc.23035. Genes Chromosomes Cancer. 2022. PMID: 35239225 Review.
A fusion gene is the product of parts of two genes that are joined together following a deletion, translocation, or chromosomal inversion. Together with single nucleotide variants, insertions, deletions, and amplification, fusion genes represent one of the key genom …
A fusion gene is the product of parts of two genes that are joined together following a deletion, translocation, or chromosomal inver …
Inpatient national trends and aggregate costs of primary and revision lumbar fusion in the US from 2016 to 2022.
Ng MK, Mastrokostas LE, Mastrokostas PG, Lee Y, Inzerillo S, Dalton J, Varthi A, Monsef JB, Razi AE, Canseco JA, Cha TD, Hilibrand AS, Vaccaro AR, Schroeder GD, Kepler CK. Ng MK, et al. Spine J. 2026 Sep;26(9):1737-1746. doi: 10.1016/j.spinee.2026.04.001. Epub 2026 Apr 13. Spine J. 2026. PMID: 41985689
Primary fusions were further categorized by approach (posterolateral fusion [PLF], posterior/transforaminal lumbar interbody fusion [PLIF/TLIF], and anterolateral interbody fusion). RESULTS: The analysis included 1,029,610 primary and 183,110 revision …
Primary fusions were further categorized by approach (posterolateral fusion [PLF], posterior/transforaminal lumbar interbody …
Recent advances in cancer fusion transcript detection.
Dorney R, Dhungel BP, Rasko JEJ, Hebbard L, Schmitz U. Dorney R, et al. Brief Bioinform. 2023 Jan 19;24(1):bbac519. doi: 10.1093/bib/bbac519. Brief Bioinform. 2023. PMID: 36527429 Free PMC article. Review.
To date, most studies have neglected chromosomal rearrangement-independent fusion transcripts and complex fusion structures such as double or triple-hop fusions, and fusion-circRNAs. In this review, we untangle fusion-related terminology and pro …
To date, most studies have neglected chromosomal rearrangement-independent fusion transcripts and complex fusion structures su …
416,699 results
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