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A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells.
Shibuya N, Koike S, Tanaka M, Ishigami-Yuasa M, Kimura Y, Ogasawara Y, Fukui K, Nagahara N, Kimura H. Shibuya N, et al. Nat Commun. 2013;4:1366. doi: 10.1038/ncomms2371. Nat Commun. 2013. PMID: 23340406
Here we report an additional biosynthetic pathway for the production of hydrogen sulphide from D-cysteine involving 3-mercaptopyruvate sulfurtransferase and D-amino acid oxidase. ...This study presents a novel pathway
Here we report an additional biosynthetic pathway for the production of hydrogen sulphide from D-cyste
d-Cysteine promotes dendritic development in primary cultured cerebellar Purkinje cells via hydrogen sulfide production.
Seki T, Sato M, Konno A, Hirai H, Kurauchi Y, Hisatsune A, Katsuki H. Seki T, et al. Mol Cell Neurosci. 2018 Dec;93:36-47. doi: 10.1016/j.mcn.2018.10.002. Epub 2018 Oct 19. Mol Cell Neurosci. 2018. PMID: 30342995
Recently, a novel pathway that generates hydrogen sulfide and reactive sulfur species from d-cysteine has been identified. d-Amino acid oxidase (DAO) is involved in this pathway and, among the various brain regions, is espec …
Recently, a novel pathway that generates hydrogen sulfide and reactive sulfur species from d-cysteine
[Availability of D-cysteine as a protectant for cerebellar neurons].
Seki T. Seki T. Nihon Yakurigaku Zasshi. 2019;154(3):133-137. doi: 10.1254/fpj.154.133. Nihon Yakurigaku Zasshi. 2019. PMID: 31527363 Japanese.
Hydrogen sulfide (H(2)S) has been focused as a biological mediator, which modulates signal transduction and protects cells and tissues from oxidative stress. ...However, it is difficult to use L-cysteine as a neuroprotectant because of its neuro
Hydrogen sulfide (H(2)S) has been focused as a biological mediator, which modulates signal transduction and protects
Signaling molecules: hydrogen sulfide and polysulfide.
Kimura H. Kimura H. Antioxid Redox Signal. 2015 Feb 10;22(5):362-76. doi: 10.1089/ars.2014.5869. Epub 2014 Jun 25. Antioxid Redox Signal. 2015. PMID: 24800864 Free PMC article. Review.
SIGNIFICANCE: Hydrogen sulfide (H2S) has been recognized as a signaling molecule as well as a cytoprotectant. It modulates neurotransmission, regulates vascular tone, and protects various tissues and organs, including neurons, the heart, and kidneys, from oxidative …
SIGNIFICANCE: Hydrogen sulfide (H2S) has been recognized as a signaling molecule as well as a cytoprotectant. It modulates neu …
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