Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2014 1
2015 2
2016 2
2017 1
2019 2
2020 1
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

9 results

Results by year

Citations

1 article found by citation matching

Search results

Filters applied: . Clear all
Page 1
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, Kawas CH, Cribbs DH, Bennett DA, Schneider JA, Larson EB, Crane PK, Valladares O, Schmitt FA, Kryscio RJ, Jicha GA, Smith CD, Scheff SW, Sonnen JA, Haines JL, Pericak-Vance MA, Mayeux R, Farrer LA, Van Eldik LJ, Horbinski C, Green RC, Gearing M, Poon LW, Kramer PL, Woltjer RL, Montine TJ, Partch AB, Rajic AJ, Richmire K, Monsell SE; Alzheimer’ Disease Genetic Consortium; Schellenberg GD, Fardo DW. Nelson PT, et al. Acta Neuropathol. 2014;127(6):825-43. doi: 10.1007/s00401-014-1282-2. Epub 2014 Apr 27. Acta Neuropathol. 2014. PMID: 24770881 Free PMC article.
Hippocampal sclerosis of aging (HS-Aging) is a high-morbidity brain disease in the elderly but risk factors are largely unknown. We report the first genome-wide association study (GWAS) with HS-Aging pathology as an endophen
Hippocampal sclerosis of aging (HS-Aging) is a high-morbidity brain disease in the elderly but risk facto
Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.
Nelson PT, Wang WX, Partch AB, Monsell SE, Valladares O, Ellingson SR, Wilfred BR, Naj AC, Wang LS, Kukull WA, Fardo DW. Nelson PT, et al. J Neuropathol Exp Neurol. 2015 Jan;74(1):75-84. doi: 10.1097/NEN.0000000000000151. J Neuropathol Exp Neurol. 2015. PMID: 25470345 Free PMC article.
Hippocampal sclerosis of aging (HS-Aging) is a common high-morbidity neurodegenerative condition in elderly persons. ...The risk for HS-Aging diagnosis associated with these genetic polymorphisms was not secondary to an a
Hippocampal sclerosis of aging (HS-Aging) is a common high-morbidity neurodegenerative condition in elder
Novel human ABCC9/SUR2 brain-expressed transcripts and an eQTL relevant to hippocampal sclerosis of aging.
Nelson PT, Wang WX, Wilfred BR, Wei A, Dimayuga J, Huang Q, Ighodaro E, Artiushin S, Fardo DW. Nelson PT, et al. J Neurochem. 2015 Sep;134(6):1026-39. doi: 10.1111/jnc.13202. Epub 2015 Jul 15. J Neurochem. 2015. PMID: 26115089 Free PMC article.
ABCC9 genetic polymorphisms are associated with increased risk for various human diseases including hippocampal sclerosis of aging. ...ABCC9 gene variants are associated with increased risk for hippocampal
ABCC9 genetic polymorphisms are associated with increased risk for various human diseases including hippocampal
CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN.
Fardo DW, Katsumata Y, Kauwe JSK, Deming Y, Harari O, Cruchaga C; Alzheimer's Disease Neuroimaging Initiative; Nelson PT. Fardo DW, et al. Exp Gerontol. 2017 Apr;90:83-89. doi: 10.1016/j.exger.2017.01.025. Epub 2017 Feb 9. Exp Gerontol. 2017. PMID: 28189700 Free PMC article.
OBJECTIVE: Hippocampal sclerosis of aging (HS-Aging) is a common cause of dementia in older adults. We tested the variability in cerebrospinal fluid (CSF) proteins associated with previously identified HS-Aging risk single nucleoti …
OBJECTIVE: Hippocampal sclerosis of aging (HS-Aging) is a common cause of dementia in older adults. We te …
Hippocampal Sclerosis of Aging, a Common Alzheimer's Disease 'Mimic': Risk Genotypes are Associated with Brain Atrophy Outside the Temporal Lobe.
Nho K, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative; Nelson PT. Nho K, et al. J Alzheimers Dis. 2016;52(1):373-83. doi: 10.3233/JAD-160077. J Alzheimers Dis. 2016. PMID: 27003218 Free PMC article.
Hippocampal sclerosis of aging (HS-Aging) is a common brain disease in older adults with a clinical course that is similar to Alzheimer's disease. ...Genetic variation associated with HS-Aging pathology may represent
Hippocampal sclerosis of aging (HS-Aging) is a common brain disease in older adults with a clinical cours
Putative risk alleles for LATE-NC with hippocampal sclerosis in population-representative autopsy cohorts.
Hokkanen SRK, Kero M, Kaivola K, Hunter S, Keage HAD, Kiviharju A, Raunio A, Tienari PJ, Paetau A, Matthews FE, Fleming J, Graff C, Polvikoski TM, Myllykangas L, Brayne C; EClipSE Collaboration. Hokkanen SRK, et al. Brain Pathol. 2020 Mar;30(2):364-372. doi: 10.1111/bpa.12773. Epub 2019 Aug 27. Brain Pathol. 2020. PMID: 31376286 Free PMC article.
Limbic-predominant age-related TAR-DNA-binding protein-43 (TDP-43) encephalopathy with hippocampal sclerosis pathology (LATE-NC + HS) is a neurodegenerative disorder characterized by severe hippocampal CA1 neuron loss and TDP-43-pathology, leadi …
Limbic-predominant age-related TAR-DNA-binding protein-43 (TDP-43) encephalopathy with hippocampal sclerosis pathology
LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry.
Katsumata Y, Fardo DW, Shade LMP; Alzheimer’s Disease Genetics Consortium; Nelson PT. Katsumata Y, et al. J Neuropathol Exp Neurol. 2023 Aug 21;82(9):760-768. doi: 10.1093/jnen/nlad059. J Neuropathol Exp Neurol. 2023. PMID: 37528055 Free PMC article.
The defining neuropathologic feature of LATE-NC is TDP-43 proteinopathy, often with comorbid hippocampal sclerosis (HS). In terms of genetic risk factors, LATE-NC and/or HS are associated with single nucleotide variants (SNVs) in 3 genes-TMEM106B (rs19 …
The defining neuropathologic feature of LATE-NC is TDP-43 proteinopathy, often with comorbid hippocampal sclerosis (HS). In te …
TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels.
Nelson PT, Gal Z, Wang WX, Niedowicz DM, Artiushin SC, Wycoff S, Wei A, Jicha GA, Fardo DW. Nelson PT, et al. Neurobiol Dis. 2019 May;125:67-76. doi: 10.1016/j.nbd.2019.01.013. Epub 2019 Jan 23. Neurobiol Dis. 2019. PMID: 30682540 Free PMC article.
The pathologies were correlated with hippocampal sclerosis of aging (HS-Aging) linked genotypes. ...This is intriguing because the SLCO1A2/IAPP and ABCC9 risk associated genotypes have been associated with altered exp …
The pathologies were correlated with hippocampal sclerosis of aging (HS-Aging) linked genotypes. . …
Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.
Nelson PT, Katsumata Y, Nho K, Artiushin SC, Jicha GA, Wang WX, Abner EL, Saykin AJ, Kukull WA; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Fardo DW. Nelson PT, et al. Acta Neuropathol. 2016 Dec;132(6):841-858. doi: 10.1007/s00401-016-1641-2. Epub 2016 Nov 4. Acta Neuropathol. 2016. PMID: 27815632 Free PMC article.
These SNPs were identified by separate research groups as risk alleles for non-Alzheimer's neurodegeneration. We found that the rs73069071 risk genotype was associated with hippocampal sclerosis (HS) pathology among people with the rs704180 risk genoty …
These SNPs were identified by separate research groups as risk alleles for non-Alzheimer's neurodegeneration. We found that the rs73069071 r …