Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1985 3
1988 1
1991 1
1992 2
1994 4
1995 4
1996 3
1997 2
1998 5
1999 3
2000 8
2001 9
2002 16
2003 31
2004 61
2005 90
2006 112
2007 88
2008 157
2009 123
2010 144
2011 150
2012 176
2013 183
2014 177
2015 191
2016 165
2017 159
2018 145
2019 160
2020 3266
2021 4031
2022 2971
2023 1803
2024 1303
2025 513

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

14,654 results

Results by year

Filters applied: . Clear all
Page 1
ACE2 Shedding and the Role in COVID-19.
Wang J, Zhao H, An Y. Wang J, et al. Front Cell Infect Microbiol. 2022 Jan 14;11:789180. doi: 10.3389/fcimb.2021.789180. eCollection 2021. Front Cell Infect Microbiol. 2022. PMID: 35096642 Free PMC article. Review.
In addition, ACE2 helps transport amino acids across the membrane. ACE2 sheds from the membrane, producing soluble ACE2 (sACE2). ...Elevated concentrations of sACE2 are more related to disease. Recombinant human ACE2, an exogenous soluble ACE2, …
In addition, ACE2 helps transport amino acids across the membrane. ACE2 sheds from the membrane, producing soluble ACE2 …
ACE2 in chronic disease and COVID-19: gene regulation and post-translational modification.
Wang CW, Chuang HC, Tan TH. Wang CW, et al. J Biomed Sci. 2023 Aug 22;30(1):71. doi: 10.1186/s12929-023-00965-9. J Biomed Sci. 2023. PMID: 37608279 Free PMC article. Review.
ACE2 protein levels are also increased by the E3 ligase PIAS4-mediated SUMOylation or the methyltransferase PRMT5-mediated ACE2 methylation, whereas ACE2 protein levels are decreased by AP2-mediated lysosomal degradation. ...In contrast, SARS-CoV-2 upregulate …
ACE2 protein levels are also increased by the E3 ligase PIAS4-mediated SUMOylation or the methyltransferase PRMT5-mediated ACE2 …
ACE2 and COVID-19: An anthropological perspective.
Samtani R, Krishna K. Samtani R, et al. Anthropol Anz. 2021 Nov 18;78(4):253-256. doi: 10.1127/anthranz/2021/1327. Anthropol Anz. 2021. PMID: 33595589 Review.
The present paper tries to review the relationship of SARS-Cov-2 infection with ACE2 expression, gene polymorphism and cardiovascular malfunctions, hypertension and type-2 diabetes. The paper highlights the fact that since ACE2 gene polymorphisms tend to be populati …
The present paper tries to review the relationship of SARS-Cov-2 infection with ACE2 expression, gene polymorphism and cardiovascular …
ACE2 and COVID-19: using antihypertensive medications and pharmacogenetic considerations.
Snyder EM, Johnson BD. Snyder EM, et al. Pharmacogenomics. 2020 Jul;21(10):695-703. doi: 10.2217/pgs-2020-0048. Epub 2020 Jun 5. Pharmacogenomics. 2020. PMID: 32501190 Free PMC article. Review.
COVID-19 utilizes the ACE2 pathway as a means of infection. Early data on COVID-19 suggest heterogeneity in the severity of symptoms during transmission and infection ranging from no symptoms to death. ...Demographic and clinical comorbidities associated with the severity …
COVID-19 utilizes the ACE2 pathway as a means of infection. Early data on COVID-19 suggest heterogeneity in the severity of symptoms …
ACE2 Regulates Glycolipid Metabolism in Multiple Tissues.
Li R, Li F, Yuan L. Li R, et al. Front Biosci (Landmark Ed). 2024 Jan 17;29(1):17. doi: 10.31083/j.fbl2901017. Front Biosci (Landmark Ed). 2024. PMID: 38287822 Free article. Review.
Angiotensin-converting enzyme 2 (ACE2) is a member of the renin-angiotensin system (RAS), which was once considered a linear cascade. ACE2 mainly functions to convert Angiotensin (Ang) to Angiotensin1-7 (A1-7). The biologically active product A1-7 then binds to the …
Angiotensin-converting enzyme 2 (ACE2) is a member of the renin-angiotensin system (RAS), which was once considered a linear cascade. …
Functional ACE2 deficiency leading to angiotensin imbalance in the pathophysiology of COVID-19.
Cook JR, Ausiello J. Cook JR, et al. Rev Endocr Metab Disord. 2022 Apr;23(2):151-170. doi: 10.1007/s11154-021-09663-z. Epub 2021 Jul 1. Rev Endocr Metab Disord. 2022. PMID: 34195965 Free PMC article. Review.
SARS-CoV-2, the virus responsible for COVID-19, uses angiotensin converting enzyme 2 (ACE2) as its primary cell-surface receptor. ACE2 is a key enzyme in the counter-regulatory pathway of the broader renin-angiotensin system (RAS) that has been implicated in a broad …
SARS-CoV-2, the virus responsible for COVID-19, uses angiotensin converting enzyme 2 (ACE2) as its primary cell-surface receptor. …
Targeting ACE2 for COVID-19 Therapy: Opportunities and Challenges.
Jia H, Neptune E, Cui H. Jia H, et al. Am J Respir Cell Mol Biol. 2021 Apr;64(4):416-425. doi: 10.1165/rcmb.2020-0322PS. Am J Respir Cell Mol Biol. 2021. PMID: 33296619 Free PMC article. Review.
Blocking this binding event or reducing the accessibility of the virus to the ACE2 receptor, represents an alternative strategy to prevent COVID-19. In addition, the biological significance of ACE2 in modulating the innate immune system and tissue repair cascades an …
Blocking this binding event or reducing the accessibility of the virus to the ACE2 receptor, represents an alternative strategy to pr …
ACE2 function in the pancreatic islet: Implications for relationship between SARS-CoV-2 and diabetes.
Memon B, Abdelalim EM. Memon B, et al. Acta Physiol (Oxf). 2021 Dec;233(4):e13733. doi: 10.1111/apha.13733. Epub 2021 Oct 2. Acta Physiol (Oxf). 2021. PMID: 34561952 Free PMC article. Review.
Importantly, ACE2 plays a crucial role in glucose homoeostasis and insulin secretion by regulating beta cell physiology. ...Also, we discuss the potential role played by ACE2 in aiding SARS-COV-2 entry into the pancreas and the possibility of ACE2 cooperation …
Importantly, ACE2 plays a crucial role in glucose homoeostasis and insulin secretion by regulating beta cell physiology. ...Also, we …
ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease.
Singh H, Choudhari R, Nema V, Khan AA. Singh H, et al. Microb Pathog. 2021 Jan;150:104621. doi: 10.1016/j.micpath.2020.104621. Epub 2020 Dec 2. Microb Pathog. 2021. PMID: 33278516 Free PMC article. Review.
BACKGROUND: A carboxypeptidase protein called ACE2 is found in many organs. ACE2 protein can play a pivotal role to regulate the pathological changes of several diseases including COVID-19. ...Hence we comprehended the occurrence of ACE2, TMPRSS2 polymorphism …
BACKGROUND: A carboxypeptidase protein called ACE2 is found in many organs. ACE2 protein can play a pivotal role to regulate t …
Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus(1).
Beacon TH, Delcuve GP, Davie JR. Beacon TH, et al. Genome. 2021 Apr;64(4):386-399. doi: 10.1139/gen-2020-0124. Epub 2020 Oct 21. Genome. 2021. PMID: 33086021 Free article. Review.
ACE2 is involved in the regulation of the renin-angiotensin system and blood pressure. ACE2 is also involved in the regulation of several signaling pathways, including integrin signaling. ...
ACE2 is involved in the regulation of the renin-angiotensin system and blood pressure. ACE2 is also involved in the regulation …
14,654 results
You have reached the last available page of results. Please see the User Guide for more information.